TissGeneSummary for SPATA31E1 |
Gene summary |
Basic gene information | Gene symbol | SPATA31E1 |
Gene name | SPATA31 subfamily E, member 1 | |
Synonyms | C9orf79|FAM75E1 | |
Cytomap | UCSC genome browser: 9q22.1 | |
Type of gene | protein-coding | |
RefGenes | NM_178828.4, | |
Description | FAM75-like protein C9orf79XXyac-YM21GA2.5family with sequence similarity 75, member E1protein FAM75E1spermatogenesis-associated protein 31E1 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000177992 | ||
HPRD : 12979 | ||
Vega : OTTHUMG00000020157 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_SPATA31E1 | |
BioGPS: 286234 | ||
Pathway | NCI Pathway Interaction Database: SPATA31E1 | |
KEGG: SPATA31E1 | ||
REACTOME: SPATA31E1 | ||
Pathway Commons: SPATA31E1 | ||
Context | iHOP: SPATA31E1 | |
ligand binding site mutation search in PubMed: SPATA31E1 | ||
UCL Cancer Institute: SPATA31E1 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of SPATA31E1 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for SPATA31E1 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for SPATA31E1 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for SPATA31E1 |
TissGeneSNV for SPATA31E1 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.D1202G | PCPG | 3 |
p.D1202G | UVM | 3 |
p.L852P | LIHC | 2 |
p.E998K | SKCM | 2 |
p.E732K | SKCM | 2 |
p.T401M | LUAD | 1 |
p.G651R | STAD | 1 |
p.H174N | LUAD | 1 |
p.E103K | SKCM | 1 |
p.W56* | LUAD | 1 |
p.P405S | SKCM | 1 |
p.R372K | SKCM | 1 |
p.E735D | LUAD | 1 |
p.E150K | HNSC | 1 |
p.E554K | SKCM | 1 |
p.G658W | LUAD | 1 |
p.S640F | SKCM | 1 |
p.G1058E | SKCM | 1 |
p.Q589* | BLCA | 1 |
p.S1157P | LIHC | 1 |
p.R632K | SKCM | 1 |
p.S1057L | SKCM | 1 |
p.G2E | SKCM | 1 |
p.S699C | HNSC | 1 |
p.Q639K | BLCA | 1 |
p.S261F | HNSC | 1 |
p.R436C | LGG | 1 |
p.I400F | SKCM | 1 |
p.R1306M | ESCA | 1 |
p.G685V | LUAD | 1 |
p.C843F | LUAD | 1 |
p.G214R | SKCM | 1 |
p.A1227T | SKCM | 1 |
p.A879T | SKCM | 1 |
p.P251L | SKCM | 1 |
p.G96R | ESCA | 1 |
p.P344S | LIHC | 1 |
p.G617R | STAD | 1 |
p.R329W | BLCA | 1 |
p.Q1440H | LGG | 1 |
p.G1336E | SKCM | 1 |
p.C1377* | LUAD | 1 |
p.G896R | SKCM | 1 |
p.R1133H | LGG | 1 |
p.T523N | ACC | 1 |
p.D301N | SKCM | 1 |
p.Q1251* | CESC | 1 |
p.S279F | SKCM | 1 |
p.R329W | LGG | 1 |
p.P359S | SKCM | 1 |
p.Q420R | LUAD | 1 |
p.G957R | SKCM | 1 |
p.L403P | PRAD | 1 |
p.E732A | SKCM | 1 |
p.G957V | LUAD | 1 |
p.P243H | LUAD | 1 |
p.Q1025* | LUAD | 1 |
p.W316C | LUAD | 1 |
p.L157X | SKCM | 1 |
p.S965C | HNSC | 1 |
p.R956S | CESC | 1 |
p.W1026* | SKCM | 1 |
p.Q502L | LUAD | 1 |
p.P532L | SKCM | 1 |
p.P194L | SKCM | 1 |
p.S1077L | BLCA | 1 |
p.H154Q | ACC | 1 |
p.T942A | ESCA | 1 |
p.G957W | LUAD | 1 |
p.G1071E | SKCM | 1 |
p.H768Y | SKCM | 1 |
p.Q853H | THYM | 1 |
p.L1171I | LUAD | 1 |
p.P923Q | LUAD | 1 |
p.P256A | HNSC | 1 |
p.L127P | STAD | 1 |
p.R1396T | ESCA | 1 |
p.P227L | SKCM | 1 |
p.V1328L | ESCA | 1 |
p.R385Q | LUAD | 1 |
p.A525D | PAAD | 1 |
p.S821F | SKCM | 1 |
p.W1026X | SKCM | 1 |
p.E43K | SKCM | 1 |
p.H348N | LUAD | 1 |
p.G1204S | SKCM | 1 |
p.G929E | SKCM | 1 |
p.G1279R | SKCM | 1 |
p.R1370T | BLCA | 1 |
p.P251T | STAD | 1 |
p.M791I | SKCM | 1 |
p.A1069S | LUAD | 1 |
p.P934S | SKCM | 1 |
p.P1383L | SKCM | 1 |
p.R1419S | HNSC | 1 |
p.I1239K | SKCM | 1 |
p.V796L | LUAD | 1 |
p.P1412S | SKCM | 1 |
p.G1039E | SKCM | 1 |
p.N901I | STAD | 1 |
p.G904R | SKCM | 1 |
p.V428A | LUAD | 1 |
p.P230S | LGG | 1 |
p.P604L | SKCM | 1 |
p.R1368H | ACC | 1 |
p.P243S | SKCM | 1 |
p.R884L | DLBC | 1 |
p.Q41* | SKCM | 1 |
p.F406L | CESC | 1 |
p.G687S | SKCM | 1 |
p.R718L | LUAD | 1 |
p.M375I | SKCM | 1 |
p.S1052R | HNSC | 1 |
p.Q1025K | SARC | 1 |
p.D715N | SKCM | 1 |
p.N283K | ACC | 1 |
p.P405L | SKCM | 1 |
p.P869S | SKCM | 1 |
p.G896E | SKCM | 1 |
p.L157* | SKCM | 1 |
p.R663K | SKCM | 1 |
p.P176Q | HNSC | 1 |
p.P805R | BLCA | 1 |
p.P405S | STAD | 1 |
p.S910N | LUAD | 1 |
p.E1408K | SKCM | 1 |
p.R787H | LGG | 1 |
p.E1002D | HNSC | 1 |
p.P1271T | HNSC | 1 |
p.T1152A | HNSC | 1 |
p.D704G | LUAD | 1 |
p.P616S | SKCM | 1 |
p.G395R | SKCM | 1 |
p.P680H | HNSC | 1 |
p.P656L | LGG | 1 |
p.G546R | LUAD | 1 |
p.R134W | CESC | 1 |
p.V559A | LGG | 1 |
p.P1420Q | LUAD | 1 |
p.P782L | SKCM | 1 |
p.D1031N | LUAD | 1 |
p.S681F | LUAD | 1 |
p.P539L | SKCM | 1 |
p.G223R | ESCA | 1 |
p.H358Y | SKCM | 1 |
p.R310K | SKCM | 1 |
p.S217L | HNSC | 1 |
p.V1156M | PRAD | 1 |
p.G814E | LGG | 1 |
p.P1043S | HNSC | 1 |
p.G957E | LGG | 1 |
p.R543K | SKCM | 1 |
p.R1115H | LUAD | 1 |
p.G352S | SKCM | 1 |
p.T271K | LUAD | 1 |
p.G163R | LUAD | 1 |
p.R385Q | BLCA | 1 |
p.S910G | HNSC | 1 |
p.V1083A | STAD | 1 |
p.F356L | ACC | 1 |
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TissGeneCNV for SPATA31E1 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for SPATA31E1 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for SPATA31E1 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for SPATA31E1 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for SPATA31E1 |
TissGeneDrug for SPATA31E1 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for SPATA31E1 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |