TissGeneSummary for ZNF829 |
Gene summary |
Basic gene information | Gene symbol | ZNF829 |
Gene name | zinc finger protein 829 | |
Synonyms | - | |
Cytomap | UCSC genome browser: 19q13.12 | |
Type of gene | protein-coding | |
RefGenes | NM_001037232.3, NM_001171979.1, | |
Description | - | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000185869 | ||
Vega : OTTHUMG00000048161 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_ZNF829 | |
BioGPS: 374899 | ||
Pathway | NCI Pathway Interaction Database: ZNF829 | |
KEGG: ZNF829 | ||
REACTOME: ZNF829 | ||
Pathway Commons: ZNF829 | ||
Context | iHOP: ZNF829 | |
ligand binding site mutation search in PubMed: ZNF829 | ||
UCL Cancer Institute: ZNF829 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of ZNF829 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for ZNF829 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
COAD | -2.833377956 | -1.574151033 | -1.259226923 | 4.39E-06 | 2.18E-05 |
HNSC | -2.522080013 | -1.135305594 | -1.386774419 | 1.63E-06 | 1.16E-05 |
ESCA | -1.40610348 | 0.215669247 | -1.621772727 | 0.00236 | 0.024993524 |
STAD | -1.505171946 | -0.429412571 | -1.075759375 | 0.000772 | 0.00434057 |
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TissGene-miRNA for ZNF829 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for ZNF829 |
TissGeneSNV for ZNF829 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.R176I | UCEC | 2 |
p.R439T | LUSC | 1 |
p.Q137* | CESC | 1 |
p.Q284H | BLCA | 1 |
p.E19K | SKCM | 1 |
p.E100K | SKCM | 1 |
p.S390* | BLCA | 1 |
p.R344I | READ | 1 |
p.S500R | BLCA | 1 |
p.E37K | ESCA | 1 |
p.R201* | HNSC | 1 |
p.C252Y | STAD | 1 |
p.Y265C | SKCM | 1 |
p.Y184C | SKCM | 1 |
p.R257I | BLCA | 1 |
p.P5S | LUAD | 1 |
p.K244R | LIHC | 1 |
p.P323L | HNSC | 1 |
p.P404L | HNSC | 1 |
p.Q203H | BLCA | 1 |
p.E241A | STAD | 1 |
p.I454V | HNSC | 1 |
p.S275R | BLCA | 1 |
p.C333Y | STAD | 1 |
p.R276P | LUSC | 1 |
p.R260I | READ | 1 |
p.Q203H | BRCA | 1 |
p.V280A | GBM | 1 |
p.S275I | BLCA | 1 |
p.R420H | PAAD | 1 |
p.V74L | READ | 1 |
p.E98Q | HNSC | 1 |
p.I233F | LUAD | 1 |
p.E412X | COAD | 1 |
p.Q363K | COAD | 1 |
p.N335K | UCEC | 1 |
p.F124Y | LUAD | 1 |
p.E356A | UCEC | 1 |
p.P115S | SKCM | 1 |
p.I373V | HNSC | 1 |
p.H343Y | CESC | 1 |
p.R501H | PAAD | 1 |
p.Q310* | CESC | 1 |
p.A54D | LUAD | 1 |
p.N475K | SKCM | 1 |
p.K209E | STAD | 1 |
p.P115L | SKCM | 1 |
p.S41F | SKCM | 1 |
p.E325V | ESCA | 1 |
p.F470S | BLCA | 1 |
p.R372K | BRCA | 1 |
p.A329V | STAD | 1 |
p.G15R | CESC | 1 |
p.R195C | COAD | 1 |
p.R400I | COAD | 1 |
p.S390* | CESC | 1 |
p.S309* | BLCA | 1 |
p.Q363* | BLCA | 1 |
p.Y251H | STAD | 1 |
p.E322A | STAD | 1 |
p.R453I | STAD | 1 |
p.W130* | LUSC | 1 |
p.S194R | BLCA | 1 |
p.G401V | ESCA | 1 |
p.K163N | STAD | 1 |
p.A135D | LUAD | 1 |
p.R282* | HNSC | 1 |
p.F44L | READ | 1 |
p.K235R | LIHC | 1 |
p.P34L | STAD | 1 |
p.K487Q | BLCA | 1 |
p.A110E | LUAD | 1 |
p.N394K | SKCM | 1 |
p.G75A | BRCA | 1 |
p.M398I | UCEC | 1 |
p.S122F | SKCM | 1 |
p.I314F | LUAD | 1 |
p.R425C | STAD | 1 |
p.P86S | LUAD | 1 |
p.R506C | STAD | 1 |
p.A248V | STAD | 1 |
p.R344I | UCEC | 1 |
p.F302L | ESCA | 1 |
p.F205Y | LUAD | 1 |
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TissGeneCNV for ZNF829 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for ZNF829 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | FusionScan | ESCA | TCGA-L5-A8NG-01A | FBL-ZNF829 | In-Frame | chr19:40327195 | chr19:37406153 |
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TissGeneNet for ZNF829 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for ZNF829 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for ZNF829 |
TissGeneDrug for ZNF829 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for ZNF829 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0009402 | Colorectal Carcinoma | 1 | BeFree |
umls:C1527249 | Colorectal Cancer | 1 | BeFree |