TissGeneSummary for SPATA31D1 |
Gene summary |
Basic gene information | Gene symbol | SPATA31D1 |
Gene name | ||
Synonyms | ||
Cytomap | UCSC genome browser: | |
Type of gene | ||
RefGenes | ||
Description | ||
Modification date | ||
dbXrefs | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_SPATA31D1 | |
BioGPS: 389762 | ||
Pathway | NCI Pathway Interaction Database: SPATA31D1 | |
KEGG: SPATA31D1 | ||
REACTOME: SPATA31D1 | ||
Pathway Commons: SPATA31D1 | ||
Context | iHOP: SPATA31D1 | |
ligand binding site mutation search in PubMed: SPATA31D1 | ||
UCL Cancer Institute: SPATA31D1 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of SPATA31D1 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for SPATA31D1 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for SPATA31D1 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for SPATA31D1 |
TissGeneSNV for SPATA31D1 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.L636V | KIRP | 2 |
p.G1306R | SKCM | 2 |
p.V994I | LGG | 2 |
p.L636V | ESCA | 2 |
p.L304* | LGG | 1 |
p.S162L | LUAD | 1 |
p.S541F | SKCM | 1 |
p.S751R | KIRC | 1 |
p.T1040A | CHOL | 1 |
p.P562R | LUAD | 1 |
p.T1313I | DLBC | 1 |
p.L616F | SKCM | 1 |
p.I719L | HNSC | 1 |
p.R964H | HNSC | 1 |
p.P158S | SKCM | 1 |
p.P1288S | SKCM | 1 |
p.R1351I | LGG | 1 |
p.S761L | PRAD | 1 |
p.G332V | LUAD | 1 |
p.K1129N | LUAD | 1 |
p.V1447E | LUAD | 1 |
p.P1543R | HNSC | 1 |
p.R692Q | STAD | 1 |
p.S369F | SKCM | 1 |
p.K1131N | SARC | 1 |
p.I1366T | KIRP | 1 |
p.S231F | SKCM | 1 |
p.Q1498* | PAAD | 1 |
p.Y446* | SARC | 1 |
p.L547R | STAD | 1 |
p.M902V | BLCA | 1 |
p.H574Y | LGG | 1 |
p.P562H | LUAD | 1 |
p.E1035K | LUAD | 1 |
p.E972K | SKCM | 1 |
p.P188S | PRAD | 1 |
p.G1389C | LUAD | 1 |
p.S1190* | LUAD | 1 |
p.S978I | SARC | 1 |
p.C279* | LGG | 1 |
p.E1376K | SKCM | 1 |
p.A1441T | SKCM | 1 |
p.K718N | CESC | 1 |
p.Q953E | BLCA | 1 |
p.H873L | ACC | 1 |
p.G770E | SKCM | 1 |
p.V886L | LUAD | 1 |
p.I399T | STAD | 1 |
p.M1249L | ESCA | 1 |
p.L144M | STAD | 1 |
p.P587T | LUAD | 1 |
p.P1543S | SKCM | 1 |
p.D783Y | STAD | 1 |
p.K1103R | LGG | 1 |
p.N733T | STAD | 1 |
p.H690Q | LUAD | 1 |
p.G432V | LUAD | 1 |
p.T1172I | DLBC | 1 |
p.E2K | HNSC | 1 |
p.V989G | STAD | 1 |
p.P556S | STAD | 1 |
p.L398F | SKCM | 1 |
p.V1297M | SARC | 1 |
p.V1297L | THYM | 1 |
p.T807S | KIRC | 1 |
p.Q1119H | ESCA | 1 |
p.Q484* | CESC | 1 |
p.A829V | ESCA | 1 |
p.Q284H | LUAD | 1 |
p.A1546V | ESCA | 1 |
p.Y772* | MESO | 1 |
p.A165E | LUAD | 1 |
p.L321M | LIHC | 1 |
p.P246L | SKCM | 1 |
p.R714S | LUAD | 1 |
p.P444Q | LUAD | 1 |
p.D230N | SARC | 1 |
p.R714H | LGG | 1 |
p.A905S | ACC | 1 |
p.K1036I | HNSC | 1 |
p.H707Y | SKCM | 1 |
p.E254K | CESC | 1 |
p.R1273M | LUAD | 1 |
p.C1277S | HNSC | 1 |
p.R692Q | ESCA | 1 |
p.S213L | SKCM | 1 |
p.L247P | HNSC | 1 |
p.P1543Q | ESCA | 1 |
p.V45M | THCA | 1 |
p.P244A | SKCM | 1 |
p.H483Y | SKCM | 1 |
p.N445Y | LUAD | 1 |
p.S1337C | HNSC | 1 |
p.F664L | LUAD | 1 |
p.Q313E | PRAD | 1 |
p.G112V | CESC | 1 |
p.I458T | LIHC | 1 |
p.P126L | ACC | 1 |
p.R422M | LIHC | 1 |
p.Q823R | LUAD | 1 |
p.V460F | HNSC | 1 |
p.P587L | SKCM | 1 |
p.R294H | STAD | 1 |
p.V780A | HNSC | 1 |
p.N57S | KIRC | 1 |
p.R1080L | LUAD | 1 |
p.L8V | SKCM | 1 |
p.G1167R | LUAD | 1 |
p.L983P | HNSC | 1 |
p.W916X | KIRP | 1 |
p.L5V | STAD | 1 |
p.D1098E | LIHC | 1 |
p.E1271K | SKCM | 1 |
p.N57I | STAD | 1 |
p.L944I | STAD | 1 |
p.H393L | BLCA | 1 |
p.S213L | BLCA | 1 |
p.F1551V | STAD | 1 |
p.R1158K | BLCA | 1 |
p.Q61* | LUAD | 1 |
p.P573L | LUAD | 1 |
p.N1528K | LUAD | 1 |
p.R1265C | ESCA | 1 |
p.S931X | UCS | 1 |
p.R913W | LUAD | 1 |
p.G1418R | LUAD | 1 |
p.S896R | KIRP | 1 |
p.E778* | HNSC | 1 |
p.Q64E | LUAD | 1 |
p.L200F | SKCM | 1 |
p.A1402D | MESO | 1 |
p.T909S | CESC | 1 |
p.V994I | PRAD | 1 |
p.R1027I | LUAD | 1 |
p.R911H | CESC | 1 |
p.T1223N | LUAD | 1 |
p.M1204T | HNSC | 1 |
p.P595L | SKCM | 1 |
p.D81N | ESCA | 1 |
p.S931* | UCS | 1 |
p.A67D | LUAD | 1 |
p.S709F | LUAD | 1 |
p.P674L | SKCM | 1 |
p.S329F | SKCM | 1 |
p.E767G | LUAD | 1 |
p.V1254M | LUAD | 1 |
p.A1451T | CESC | 1 |
p.S990Y | ESCA | 1 |
p.W359L | HNSC | 1 |
p.G1243D | SKCM | 1 |
p.S369C | LGG | 1 |
p.M902L | PAAD | 1 |
p.S1433F | SKCM | 1 |
p.R833C | LUAD | 1 |
p.M766I | LUAD | 1 |
p.P789L | LGG | 1 |
p.T1285M | BLCA | 1 |
p.Q1270H | LIHC | 1 |
p.S84T | DLBC | 1 |
p.R964C | HNSC | 1 |
p.Q1343X | KIRC | 1 |
p.S213L | SARC | 1 |
p.A1176V | HNSC | 1 |
p.E865Q | BLCA | 1 |
p.V1100A | ESCA | 1 |
p.R1027I | HNSC | 1 |
p.G954R | SKCM | 1 |
p.A388D | LUAD | 1 |
p.W82X | DLBC | 1 |
p.R1265C | PAAD | 1 |
p.V886I | KIRP | 1 |
p.Q583* | BLCA | 1 |
p.K134N | LUAD | 1 |
p.S1006Y | ESCA | 1 |
p.E1303K | PAAD | 1 |
p.R874* | PCPG | 1 |
p.G1329E | SKCM | 1 |
p.Q1359E | CESC | 1 |
p.R1188I | THYM | 1 |
p.G345V | HNSC | 1 |
p.P1093S | LUAD | 1 |
p.L247F | SKCM | 1 |
p.S273L | SKCM | 1 |
p.R422S | LUAD | 1 |
p.K795N | ACC | 1 |
p.F1396L | LUAD | 1 |
p.S51L | SKCM | 1 |
p.G701C | LUAD | 1 |
p.W916* | KIRP | 1 |
p.S349T | THYM | 1 |
p.H574N | LUAD | 1 |
p.H623Y | SKCM | 1 |
p.D796Y | KIRP | 1 |
p.S1112R | KIRC | 1 |
p.H607Q | LUAD | 1 |
p.Q1498X | PAAD | 1 |
p.G432* | LUAD | 1 |
p.L200P | STAD | 1 |
p.S265R | SARC | 1 |
p.P1148L | LUAD | 1 |
p.R1410K | SKCM | 1 |
p.S1473C | ESCA | 1 |
p.R131Q | DLBC | 1 |
p.D796N | SKCM | 1 |
p.R714H | HNSC | 1 |
p.E1183K | SKCM | 1 |
p.R1316H | KIRP | 1 |
p.P1515S | SKCM | 1 |
p.L304X | LGG | 1 |
p.E379K | SKCM | 1 |
p.L592I | LUAD | 1 |
p.E682K | HNSC | 1 |
p.G1142C | HNSC | 1 |
p.C309F | LUAD | 1 |
p.R1158S | BLCA | 1 |
p.D183H | ESCA | 1 |
p.E167Q | HNSC | 1 |
p.L1210V | STAD | 1 |
p.R874X | PCPG | 1 |
p.S1179F | SARC | 1 |
p.A152T | LUAD | 1 |
p.S155F | SKCM | 1 |
p.P988T | LUAD | 1 |
p.K858N | CESC | 1 |
p.S580F | SKCM | 1 |
p.S1168G | BLCA | 1 |
p.E1503V | LUAD | 1 |
p.E1014K | SKCM | 1 |
p.T1409S | LUAD | 1 |
p.L983F | SKCM | 1 |
p.S557R | LUAD | 1 |
p.W626* | SKCM | 1 |
p.L935P | ESCA | 1 |
p.G917S | LUAD | 1 |
p.R122L | LUAD | 1 |
p.P703S | DLBC | 1 |
p.V1542F | LUAD | 1 |
p.E839D | LUAD | 1 |
p.A153T | LUAD | 1 |
p.W471L | LUAD | 1 |
p.P188T | LUAD | 1 |
p.T1157I | SARC | 1 |
p.E182V | HNSC | 1 |
p.P1428L | SKCM | 1 |
p.S333F | BLCA | 1 |
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TissGeneCNV for SPATA31D1 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for SPATA31D1 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for SPATA31D1 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for SPATA31D1 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for SPATA31D1 |
TissGeneDrug for SPATA31D1 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for SPATA31D1 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |