TissGeneSummary for OR52D1 |
Gene summary |
Basic gene information | Gene symbol | OR52D1 |
Gene name | olfactory receptor, family 52, subfamily D, member 1 | |
Synonyms | OR11-43 | |
Cytomap | UCSC genome browser: 11p15.4 | |
Type of gene | protein-coding | |
RefGenes | NM_001005163.2, | |
Description | HOR 5'Beta14odorant receptor HOR5'beta14olfactory receptor 52D1olfactory receptor OR11-43 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000181609 | ||
HPRD : 15008 | ||
Vega : OTTHUMG00000066895 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_OR52D1 | |
BioGPS: 390066 | ||
Pathway | NCI Pathway Interaction Database: OR52D1 | |
KEGG: OR52D1 | ||
REACTOME: OR52D1 | ||
Pathway Commons: OR52D1 | ||
Context | iHOP: OR52D1 | |
ligand binding site mutation search in PubMed: OR52D1 | ||
UCL Cancer Institute: OR52D1 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of OR52D1 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
Top |
TissGeneExp for OR52D1 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
Top |
TissGene-miRNA for OR52D1 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
Top |
TissGeneMut for OR52D1 |
TissGeneSNV for OR52D1 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.S96F | SKCM | 5 |
p.A31V | STAD | 2 |
p.S317* | PAAD | 1 |
p.L291P | STAD | 1 |
p.R306Q | SKCM | 1 |
p.G173V | LUAD | 1 |
p.L68I | LUAD | 1 |
p.E302* | LAML | 1 |
p.H269D | LUSC | 1 |
p.P257R | LUAD | 1 |
p.R146K | SKCM | 1 |
p.K315E | PAAD | 1 |
p.R304W | SKCM | 1 |
p.S96T | GBM | 1 |
p.A26V | UCEC | 1 |
p.A188T | ACC | 1 |
p.S242N | COAD | 1 |
p.V143D | PCPG | 1 |
p.G268R | ACC | 1 |
p.I87T | KIRP | 1 |
p.R175H | STAD | 1 |
p.S155T | BRCA | 1 |
p.R154H | LUAD | 1 |
p.E302D | SKCM | 1 |
p.L212M | SKCM | 1 |
p.S220F | SKCM | 1 |
p.S317X | PAAD | 1 |
p.I224T | UCEC | 1 |
p.L88F | BLCA | 1 |
p.P161L | SKCM | 1 |
p.F28I | UCEC | 1 |
p.A206V | COAD | 1 |
p.A206D | LUSC | 1 |
p.L69F | UCEC | 1 |
p.M54I | HNSC | 1 |
p.S233F | BLCA | 1 |
p.A53S | STAD | 1 |
p.R189P | LGG | 1 |
p.L231H | CESC | 1 |
p.P257T | LUAD | 1 |
p.L225F | SKCM | 1 |
p.T264A | UCEC | 1 |
p.D213Y | STAD | 1 |
p.S246F | SKCM | 1 |
p.I251T | COAD | 1 |
p.S116L | SKCM | 1 |
p.L133I | SKCM | 1 |
p.P82L | SKCM | 1 |
p.E302K | SKCM | 1 |
p.S246A | PRAD | 1 |
p.M121L | LIHC | 1 |
p.R304W | READ | 1 |
p.T72I | LUAD | 1 |
p.A112T | SKCM | 1 |
p.D55G | STAD | 1 |
p.R154C | BRCA | 1 |
p.G22W | LGG | 1 |
p.C67* | LUAD | 1 |
p.T264I | PRAD | 1 |
p.G297* | SKCM | 1 |
p.L231P | ESCA | 1 |
p.R304W | STAD | 1 |
p.G297X | SKCM | 1 |
p.D213N | SKCM | 1 |
p.T204A | HNSC | 1 |
p.G22E | SKCM | 1 |
p.A258V | SKCM | 1 |
p.H10R | HNSC | 1 |
p.P21S | LUSC | 1 |
Top |
TissGeneCNV for OR52D1 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
Top |
TissGeneFusions for OR52D1 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Top |
TissGeneNet for OR52D1 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
Top |
TissGeneProg for OR52D1 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Top |
TissGeneClin for OR52D1 |
TissGeneDrug for OR52D1 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
TissGeneDisease for OR52D1 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0027404 | Narcolepsy | 1 | GAD |