 |
| |
| |
| |
| |
| |
| |
|
| TissGeneSummary for NOX4 |
 Gene summary |
| Basic gene information | Gene symbol | NOX4 |
| Gene name | NADPH oxidase 4 | |
| Synonyms | KOX|KOX-1|RENOX | |
| Cytomap | UCSC genome browser: 11q14.2-q21 | |
| Type of gene | protein-coding | |
| RefGenes | NM_001143836.2, NM_001143837.1,NM_001291926.1,NM_001291927.1,NM_001291929.1, NM_001300995.1,NM_016931.4,NR_026571.1,NR_120406.1, | |
| Description | kidney oxidase-1kidney superoxide-producing NADPH oxidaserenal NAD(P)H-oxidase | |
| Modification date | 20141207 | |
| dbXrefs | MIM : 605261 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000086991 | ||
| HPRD : 09243 | ||
| Vega : OTTHUMG00000167298 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_NOX4 | |
| BioGPS: 50507 | ||
| Pathway | NCI Pathway Interaction Database: NOX4 | |
| KEGG: NOX4 | ||
| REACTOME: NOX4 | ||
| Pathway Commons: NOX4 | ||
| Context | iHOP: NOX4 | |
| ligand binding site mutation search in PubMed: NOX4 | ||
| UCL Cancer Institute: NOX4 | ||
| Assigned class in TissGDB* | A | |
| Included tissue-specific gene expression resources | HPA,TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Kidney | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | KIRC,KIRP,KICH | |
| Reference showing the relevant tissue of NOX4 | Role of Nox4 in murine models of kidney disease. Babelova A, Avaniadi D, Jung O, Fork C, Beckmann J, Kosowski J, Weissmann N, Anilkumar N, Shah AM, Schaefer L, Schröder K, Brandes RP. Free Radic Biol Med. 2012 Aug 15;53(4):842-53. doi: 10.1016/j.freeradbiomed.2012.06.027. Epub 2012 Jun 27. (pmid:22749956) go to article | |
| Description by TissGene annotations | Cancer gene | |
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID | GO:0050667 | homocysteine metabolic process | 20031578 | GO:0055114 | oxidation-reduction process | 10869423 | GO:0072593 | reactive oxygen species metabolic process | 10869423 | GO:0050667 | homocysteine metabolic process | 20031578 | GO:0055114 | oxidation-reduction process | 10869423 | GO:0072593 | reactive oxygen species metabolic process | 10869423 |
| Top |
| TissGeneExp for NOX4 |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
 |
| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
 |
| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| LUAD | 0.857107109 | -0.571746339 | 1.428853448 | 1.96E-07 | 7.34E-07 |
| LIHC | -0.66874165 | -3.57091365 | 2.902172 | 3.08E-24 | 5.26E-22 |
| LUSC | 1.024517488 | -0.267608003 | 1.29212549 | 1.35E-06 | 3.33E-06 |
| COAD | -0.135383342 | -3.333167957 | 3.197784615 | 2.41E-10 | 3.11E-09 |
| STAD | -0.1182944 | -2.118560025 | 2.000265625 | 1.70E-06 | 2.57E-05 |
| THCA | 1.418203164 | -1.266983277 | 2.685186441 | 3.38E-22 | 1.97E-20 |
| HNSC | 0.849858071 | -1.257009371 | 2.106867442 | 9.14E-10 | 1.52E-08 |
| BRCA | 2.138872596 | 1.073865578 | 1.065007018 | 4.74E-07 | 1.33E-06 |
| PRAD | -1.107041034 | -2.891129496 | 1.784088462 | 9.09E-09 | 1.13E-07 |
| KIRP | 3.35449935 | 4.61193685 | -1.2574375 | 0.0178 | 0.036511985 |
| ESCA | -0.659152922 | -2.875080195 | 2.215927273 | 0.00341 | 0.031045224 |
| Top |
| TissGene-miRNA for NOX4 |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
| Top |
| TissGeneMut for NOX4 |
| TissGeneSNV for NOX4 |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
 |
 |
| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
 |
| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.K554N | UCEC | 1 |
| p.S244* | BRCA | 1 |
| p.G310* | CESC | 1 |
| p.P136S | SKCM | 1 |
| p.I373T | BLCA | 1 |
| p.L50F | OV | 1 |
| p.L454F | GBM | 1 |
| p.P320A | LIHC | 1 |
| p.G524* | LUAD | 1 |
| p.N526I | ESCA | 1 |
| p.Q24H | ACC | 1 |
| p.Q313* | BLCA | 1 |
| p.W284C | LUSC | 1 |
| p.Y191F | ESCA | 1 |
| p.E217K | SKCM | 1 |
| p.S389C | HNSC | 1 |
| p.K100N | READ | 1 |
| p.R358* | LUAD | 1 |
| p.E370K | ESCA | 1 |
| p.L356I | ESCA | 1 |
| p.R102G | DLBC | 1 |
| p.G230E | SKCM | 1 |
| p.L40P | ESCA | 1 |
| p.R382* | PAAD | 1 |
| p.R72K | LGG | 1 |
| p.A490P | LIHC | 1 |
| p.L40I | LUAD | 1 |
| p.K153I | LIHC | 1 |
| p.E116Q | BLCA | 1 |
| p.S369Y | LUAD | 1 |
| p.R147Q | COAD | 1 |
| p.S281T | LUAD | 1 |
| p.V350A | LGG | 1 |
| p.E305K | SKCM | 1 |
| p.I349T | BLCA | 1 |
| p.F469V | GBM | 1 |
| p.Y215F | ESCA | 1 |
| p.Y242F | LUSC | 1 |
| p.F255I | KIRC | 1 |
| p.A143T | STAD | 1 |
| p.S420L | COAD | 1 |
| p.R382* | LUAD | 1 |
| p.V159F | STAD | 1 |
| p.N206I | LUAD | 1 |
| p.E136K | LUSC | 1 |
| p.E299K | SKCM | 1 |
| p.I417R | KIRC | 1 |
| p.S7T | STAD | 1 |
| p.G254E | SKCM | 1 |
| p.I441R | KIRC | 1 |
| p.A514P | LIHC | 1 |
| p.T205M | GBM | 1 |
| p.G351E | UCS | 1 |
| p.R71W | LIHC | 1 |
| p.R95W | LIHC | 1 |
| p.E370K | SKCM | 1 |
| p.Q258E | LUAD | 1 |
| p.P66L | SKCM | 1 |
| p.L149P | ESCA | 1 |
| p.S347F | SKCM | 1 |
| p.R301* | LUAD | 1 |
| p.Q476E | LUAD | 1 |
| p.F130L | DLBC | 1 |
| p.S288F | SKCM | 1 |
| p.V170L | LUSC | 1 |
| p.F231I | KIRC | 1 |
| p.G351E | CHOL | 1 |
| p.A439S | STAD | 1 |
| p.R569I | UCEC | 1 |
| p.Q39R | ESCA | 1 |
| p.G161S | BRCA | 1 |
| p.K244N | BLCA | 1 |
| p.G539E | SKCM | 1 |
| p.R464I | BLCA | 1 |
| p.N38D | HNSC | 1 |
| p.S576Y | DLBC | 1 |
| p.H23Q | BLCA | 1 |
| p.I484S | LIHC | 1 |
| p.Q15R | ESCA | 1 |
| p.P320L | PAAD | 1 |
| p.I324M | UCEC | 1 |
| p.R356Q | SKCM | 1 |
| p.S517L | SKCM | 1 |
| p.F417S | UCEC | 1 |
| p.K406R | ESCA | 1 |
| p.S365C | HNSC | 1 |
| p.G567V | LUSC | 1 |
| p.E149V | BLCA | 1 |
| p.P344L | PAAD | 1 |
| p.I508S | LIHC | 1 |
| p.S316R | STAD | 1 |
| p.R455K | UCEC | 1 |
| p.K268N | UCEC | 1 |
| p.E241K | SKCM | 1 |
| p.D386N | ESCA | 1 |
| p.K265I | COAD | 1 |
| p.Q500E | LUAD | 1 |
| p.S233T | LUSC | 1 |
| p.C404W | LUAD | 1 |
| p.R382X | PAAD | 1 |
| p.A235E | LUAD | 1 |
| p.H342R | COAD | 1 |
| p.S23Y | STAD | 1 |
| p.V492I | UCEC | 1 |
| p.E394K | UCEC | 1 |
| p.G375E | CHOL | 1 |
| p.Q48H | ACC | 1 |
| p.E323K | SKCM | 1 |
| p.S323F | SKCM | 1 |
| p.S264F | SKCM | 1 |
| p.R464K | LUSC | 1 |
| p.S493L | SKCM | 1 |
| p.R358* | PAAD | 1 |
| p.K450I | UCEC | 1 |
| p.L261P | SKCM | 1 |
| p.V118M | COAD | 1 |
| p.H47Q | BLCA | 1 |
| p.A348T | THYM | 1 |
| p.E394K | ESCA | 1 |
| p.G265* | LUAD | 1 |
| p.D447Y | STAD | 1 |
| p.S393Y | LUAD | 1 |
| p.G375E | PAAD | 1 |
| p.H16R | STAD | 1 |
| p.Q337* | BLCA | 1 |
| p.F483I | LUAD | 1 |
| p.S107L | BLCA | 1 |
| p.R525L | DLBC | 1 |
| p.D410N | ESCA | 1 |
| p.S232L | SKCM | 1 |
| p.A61T | UCEC | 1 |
| Top |
| TissGeneCNV for NOX4 |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
 |
| Top |
| TissGeneFusions for NOX4 |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| TCGAfusionPortal | PRADA | BRCA | TCGA-A1-A0SJ-01A | ZFP91-NOX4 | In-frame | Chr11:58352357 | Chr11:89088211 |
| TCGAfusionPortal | PRADA | BRCA | TCGA-BH-A18L-01A | LRP5-NOX4 | Out-of-frame | Chr11:68207384 | Chr11:89088211 |
| TCGAfusionPortal | PRADA | BRCA | TCGA-E9-A229-01A | NFRKB-NOX4 | Out-of-frame | Chr11:129755330 | Chr11:89135710 |
| Top |
| TissGeneNet for NOX4 |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| COAD (tumor) | COAD (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| HNSC (tumor) | HNSC (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| KICH (tumor) | KICH (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| KIRC (tumor) | KIRC (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| KIRP (tumor) | KIRP (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| LIHC (tumor) | LIHC (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| LUAD (tumor) | LUAD (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| LUSC (tumor) | LUSC (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| PRAD (tumor) | PRAD (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| STAD (tumor) | STAD (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| THCA (tumor) | THCA (normal) |
| NOX4, RELA, TLR4 (tumor) | NOX4, RELA, TLR4 (normal) |
 |  |
| Top |
| TissGeneProg for NOX4 |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
 |
| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Top |
| TissGeneClin for NOX4 |
| TissGeneDrug for NOX4 |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Top |
| TissGeneDisease for NOX4 |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0011881 | Diabetic Nephropathy | 6 | BeFree,RGD |
| umls:C0011847 | Diabetes | 4 | BeFree |
| umls:C0011849 | Diabetes Mellitus | 4 | BeFree |
| umls:C0017636 | Glioblastoma | 4 | BeFree |
| umls:C0022116 | Ischemia | 4 | BeFree |
| umls:C0235974 | Pancreatic carcinoma | 4 | BeFree |
| umls:C0239946 | Fibrosis, Liver | 4 | BeFree |
| umls:C0346647 | Malignant neoplasm of pancreas | 4 | BeFree |
| umls:C2239176 | Liver carcinoma | 4 | BeFree |
| umls:C0007102 | Malignant tumor of colon | 3 | BeFree |
| umls:C0020456 | Hyperglycemia | 3 | BeFree |
| umls:C0020538 | Hypertensive disease | 3 | LHGDN,RGD |
| umls:C0020542 | Pulmonary Hypertension | 3 | BeFree,LHGDN |
| umls:C0025202 | melanoma | 3 | BeFree |
| umls:C0030297 | Pancreatic Neoplasm | 3 | LHGDN |
| umls:C0007131 | Non-Small Cell Lung Carcinoma | 2 | BeFree |
| umls:C0007134 | Renal Cell Carcinoma | 2 | BeFree |
| umls:C0007222 | Cardiovascular Diseases | 2 | BeFree |
| umls:C0018801 | Heart failure | 2 | BeFree,CTD_human |
| umls:C0019196 | Hepatitis C | 2 | BeFree |
| umls:C0022661 | Kidney Failure, Chronic | 2 | BeFree,CTD_human |
| umls:C0027430 | Nasal Polyps | 2 | BeFree |
| umls:C0152171 | Idiopathic pulmonary hypertension | 2 | BeFree |
| umls:C0178874 | Tumor Progression | 2 | BeFree |
| umls:C0596263 | Carcinogenesis | 2 | BeFree |
| umls:C0699790 | Colon Carcinoma | 2 | BeFree |
| umls:C1800706 | Idiopathic Pulmonary Fibrosis | 2 | BeFree |
| umls:C3203102 | Idiopathic pulmonary arterial hypertension | 2 | BeFree |
| umls:C0002736 | Amyotrophic Lateral Sclerosis | 1 | GAD |
| umls:C0002940 | Aneurysm | 1 | RGD |
| umls:C0003130 | Anoxia | 1 | LHGDN |
| umls:C0003486 | Aortic Aneurysm | 1 | BeFree |
| umls:C0004096 | Asthma | 1 | BeFree,LHGDN |
| umls:C0004114 | Astrocytoma | 1 | BeFree |
| umls:C0006142 | Malignant neoplasm of breast | 1 | BeFree |
| umls:C0009375 | Colonic Neoplasms | 1 | CTD_human |
| umls:C0010054 | Coronary Arteriosclerosis | 1 | BeFree |
| umls:C0011853 | Diabetes Mellitus, Experimental | 1 | RGD |
| umls:C0011854 | Diabetes Mellitus, Insulin-Dependent | 1 | BeFree |
| umls:C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | GAD |
| umls:C0011875 | Diabetic Angiopathies | 1 | BeFree |
| umls:C0016781 | Fuchs Endothelial Dystrophy | 1 | BeFree |
| umls:C0017638 | Glioma | 1 | BeFree,LHGDN |
| umls:C0018802 | Congestive heart failure | 1 | BeFree |
| umls:C0019693 | HIV Infections | 1 | GAD |
| umls:C0020459 | Hyperinsulinism | 1 | BeFree |
| umls:C0022660 | Kidney Failure, Acute | 1 | BeFree |
| umls:C0022665 | Kidney Neoplasm | 1 | BeFree |
| umls:C0023418 | leukemia | 1 | LHGDN |
| umls:C0023890 | Liver Cirrhosis | 1 | GAD |
| umls:C0023903 | Liver neoplasms | 1 | BeFree |
| umls:C0026636 | Mouth Diseases | 1 | BeFree |
| umls:C0027627 | Neoplasm Metastasis | 1 | BeFree |
| umls:C0027796 | Neuralgia | 1 | BeFree |
| umls:C0029456 | Osteoporosis | 1 | BeFree |
| umls:C0034069 | Pulmonary Fibrosis | 1 | BeFree |
| umls:C0035126 | Reperfusion Injury | 1 | RGD |
| umls:C0035309 | Retinal Diseases | 1 | BeFree |
| umls:C0038454 | Cerebrovascular accident | 1 | BeFree |
| umls:C0040336 | Tobacco Use Disorder | 1 | GAD |
| umls:C0042373 | Vascular Diseases | 1 | BeFree |
| umls:C0153676 | Secondary malignant neoplasm of lung | 1 | BeFree |
| umls:C0153690 | Secondary malignant neoplasm of bone | 1 | BeFree |
| umls:C0154830 | Proliferative diabetic retinopathy | 1 | BeFree |
| umls:C0162770 | Right Ventricular Hypertrophy | 1 | BeFree |
| umls:C0206715 | Neoplasms, Neuroepithelial | 1 | BeFree |
| umls:C0241910 | Hepatitis, Autoimmune | 1 | BeFree |
| umls:C0242379 | Malignant neoplasm of lung | 1 | BeFree |
| umls:C0278996 | Cancer of Head and Neck | 1 | BeFree |
| umls:C0279000 | Liver and Intrahepatic Biliary Tract Carcinoma | 1 | BeFree |
| umls:C0280100 | Solid tumour | 1 | BeFree |
| umls:C0281361 | Adenocarcinoma of pancreas | 1 | BeFree |
| umls:C0338106 | Adenocarcinoma of colon | 1 | BeFree |
| umls:C0345904 | Malignant neoplasm of liver | 1 | BeFree |
| umls:C0524620 | Metabolic Syndrome X | 1 | BeFree |
| umls:C0524910 | Hepatitis C, Chronic | 1 | BeFree |
| umls:C0549473 | Thyroid carcinoma | 1 | BeFree |
| umls:C0600452 | Hepatopulmonary Syndrome | 1 | GAD |
| umls:C0678222 | Breast Carcinoma | 1 | BeFree |
| umls:C0684249 | Carcinoma of lung | 1 | BeFree |
| umls:C0686619 | Secondary malignant neoplasm of lymph node | 1 | BeFree |
| umls:C0856169 | Endothelial dysfunction | 1 | BeFree |
| umls:C0876973 | Infectious disease of lung | 1 | BeFree |
| umls:C0919267 | ovarian neoplasm | 1 | BeFree |
| umls:C1168401 | Squamous cell carcinoma of the head and neck | 1 | BeFree |
| umls:C1335302 | Pancreatic Ductal Adenocarcinoma | 1 | BeFree |
| umls:C1397307 | Cardiac fibrosis | 1 | BeFree |
| umls:C1458155 | Mammary Neoplasms | 1 | BeFree |
| umls:C1512409 | Hepatocarcinogenesis | 1 | BeFree |
| umls:C2711227 | Steatohepatitis | 1 | BeFree |
| umls:C2931852 | Clear-cell metastatic renal cell carcinoma | 1 | BeFree |
| umls:C3241937 | Nonalcoholic Steatohepatitis | 1 | BeFree |
Copyright 2016-Present - The University of Texas Health Science Center at Houston (UTHealth) Web File Viewing | How to Report, Fraud, Waste and Abuse | State of Texas | Statewide Search | Texas Homeland Security | Site Policies |