TissGeneSummary for CAMKV |
Gene summary |
Basic gene information | Gene symbol | CAMKV |
Gene name | CaM kinase-like vesicle-associated | |
Synonyms | 1G5|VACAMKL | |
Cytomap | UCSC genome browser: 3p21.31 | |
Type of gene | protein-coding | |
RefGenes | NM_024046.3, | |
Description | caM kinase-like vesicle-associated proteinvesicle-associated calmodulin-binding protein | |
Modification date | 20141207 | |
dbXrefs | MIM : 614993 | |
HGNC : HGNC | ||
Ensembl : ENSG00000164076 | ||
HPRD : 11361 | ||
Vega : OTTHUMG00000158288 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_CAMKV | |
BioGPS: 79012 | ||
Pathway | NCI Pathway Interaction Database: CAMKV | |
KEGG: CAMKV | ||
REACTOME: CAMKV | ||
Pathway Commons: CAMKV | ||
Context | iHOP: CAMKV | |
ligand binding site mutation search in PubMed: CAMKV | ||
UCL Cancer Institute: CAMKV | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,TiGER | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Brain | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | GBM,LGG | |
Reference showing the relevant tissue of CAMKV | ||
Description by TissGene annotations | Cancer gene |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for CAMKV |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
COAD | 0.737548818 | -1.417362721 | 2.154911538 | 4.51E-05 | 0.000177404 |
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TissGene-miRNA for CAMKV |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for CAMKV |
TissGeneSNV for CAMKV |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.R58W | LGG | 1 |
p.R424K | UCEC | 1 |
p.D468N | SKCM | 1 |
p.R497K | LAML | 1 |
p.I141T | STAD | 1 |
p.L8P | STAD | 1 |
p.D228N | BLCA | 1 |
p.T109A | UCEC | 1 |
p.A406V | LGG | 1 |
p.P388Q | LUAD | 1 |
p.D293H | ESCA | 1 |
p.A429T | SKCM | 1 |
p.R92H | OV | 1 |
p.E173Q | CESC | 1 |
p.V142M | ESCA | 1 |
p.N217D | GBM | 1 |
p.S118L | BRCA | 1 |
p.R156W | LGG | 1 |
p.E268K | SKCM | 1 |
p.Q303H | LUAD | 1 |
p.S128L | UCEC | 1 |
p.R327W | STAD | 1 |
p.R92H | THYM | 1 |
p.A429G | COAD | 1 |
p.K12N | UCEC | 1 |
p.V191M | SKCM | 1 |
p.I97M | BLCA | 1 |
p.P123L | UCEC | 1 |
p.D233N | SKCM | 1 |
p.D391N | SKCM | 1 |
p.G193D | UCEC | 1 |
p.G193S | SKCM | 1 |
p.A132V | SKCM | 1 |
p.I304F | LUAD | 1 |
p.P327L | SKCM | 1 |
p.I30T | STAD | 1 |
p.V125A | UCEC | 1 |
p.A335T | SKCM | 1 |
p.E119G | STAD | 1 |
p.P250A | LUAD | 1 |
p.G60S | STAD | 1 |
p.L236F | SKCM | 1 |
p.L213R | COAD | 1 |
p.S501I | LUAD | 1 |
p.R196W | COAD | 1 |
p.E70K | HNSC | 1 |
p.K234N | THCA | 1 |
p.D25N | SKCM | 1 |
p.A479T | UCEC | 1 |
p.S385N | LUAD | 1 |
p.S292C | LUAD | 1 |
p.P460T | LUAD | 1 |
p.R372C | PRAD | 1 |
p.A205T | SKCM | 1 |
p.D407N | STAD | 1 |
p.D113N | SKCM | 1 |
p.K75N | UCEC | 1 |
p.P200L | SKCM | 1 |
p.D43N | SKCM | 1 |
p.P467Q | GBM | 1 |
p.T321I | SKCM | 1 |
p.P338L | LUAD | 1 |
p.E279K | SKCM | 1 |
p.D228H | BLCA | 1 |
p.K306N | UCEC | 1 |
p.I177V | STAD | 1 |
p.T430I | SKCM | 1 |
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TissGeneCNV for CAMKV |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for CAMKV |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | ChiTaRs | NA | X94700 | CAMKV-CABP1 | chr3:49899839 | chr12:121098600 |
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TissGeneNet for CAMKV |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for CAMKV |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for CAMKV |
TissGeneDrug for CAMKV |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for CAMKV |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0036341 | Schizophrenia | 1 | GAD |