TissGeneSummary for ZNF628 |
Gene summary |
Basic gene information | Gene symbol | ZNF628 |
Gene name | zinc finger protein 628 | |
Synonyms | ZEC|Zfp628 | |
Cytomap | UCSC genome browser: 19q13.42 | |
Type of gene | protein-coding | |
RefGenes | NM_033113.2, | |
Description | zinc finger protein Zec | |
Modification date | 20141207 | |
dbXrefs | MIM : 610671 | |
HGNC : HGNC | ||
Ensembl : ENSG00000197483 | ||
HPRD : 18317 | ||
Vega : OTTHUMG00000150396 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_ZNF628 | |
BioGPS: 89887 | ||
Pathway | NCI Pathway Interaction Database: ZNF628 | |
KEGG: ZNF628 | ||
REACTOME: ZNF628 | ||
Pathway Commons: ZNF628 | ||
Context | iHOP: ZNF628 | |
ligand binding site mutation search in PubMed: ZNF628 | ||
UCL Cancer Institute: ZNF628 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | TiGER,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | SkinTestis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | SKCMTGCT | |
Reference showing the relevant tissue of ZNF628 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for ZNF628 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for ZNF628 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for ZNF628 |
TissGeneSNV for ZNF628 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.T234A | ACC | 9 |
p.T230A | COAD | 3 |
p.F590L | HNSC | 1 |
p.L517I | STAD | 1 |
p.P14L | SKCM | 1 |
p.T195M | UCEC | 1 |
p.A837V | PAAD | 1 |
p.G460D | MESO | 1 |
p.R142C | UCEC | 1 |
p.P150R | ACC | 1 |
p.D471E | STAD | 1 |
p.Q860P | LIHC | 1 |
p.Q968H | UCEC | 1 |
p.G655D | PAAD | 1 |
p.D475E | STAD | 1 |
p.P154R | ACC | 1 |
p.P154H | PAAD | 1 |
p.C62F | LUAD | 1 |
p.V936M | PRAD | 1 |
p.T853M | STAD | 1 |
p.T849M | STAD | 1 |
p.R592Q | STAD | 1 |
p.T860M | STAD | 1 |
p.V850I | SKCM | 1 |
p.H134L | KIRP | 1 |
p.T230A | READ | 1 |
p.K158R | LUAD | 1 |
p.C539Y | LGG | 1 |
p.G791R | ESCA | 1 |
p.R820Q | UCEC | 1 |
p.P904L | HNSC | 1 |
p.F153L | LUAD | 1 |
p.T827A | BLCA | 1 |
p.R588W | STAD | 1 |
p.T863S | LUAD | 1 |
p.H562Q | BLCA | 1 |
p.V439A | UCS | 1 |
p.G456C | STAD | 1 |
p.T182M | STAD | 1 |
p.S467P | SARC | 1 |
p.F594L | HNSC | 1 |
p.A9V | COAD | 1 |
p.A13V | PAAD | 1 |
p.A833V | PAAD | 1 |
p.E885Q | CESC | 1 |
p.T186M | STAD | 1 |
p.D921Y | LIHC | 1 |
p.A9V | PAAD | 1 |
p.E19D | ESCA | 1 |
p.R758Q | HNSC | 1 |
p.T902N | STAD | 1 |
p.E23D | ESCA | 1 |
p.V435A | COAD | 1 |
p.T864M | STAD | 1 |
p.T505M | LUAD | 1 |
p.R103H | PAAD | 1 |
p.A787V | CHOL | 1 |
p.R752H | STAD | 1 |
p.E292D | ACC | 1 |
p.R756H | STAD | 1 |
p.P954T | COAD | 1 |
p.A546S | LUAD | 1 |
p.Q799* | UCEC | 1 |
p.G628S | STAD | 1 |
p.G179A | PAAD | 1 |
p.R592W | STAD | 1 |
p.G817W | LUAD | 1 |
p.V947I | READ | 1 |
p.L513I | STAD | 1 |
p.A235V | KIRP | 1 |
p.R46W | STAD | 1 |
p.G659D | PAAD | 1 |
p.L605M | UCEC | 1 |
p.R582Q | BLCA | 1 |
p.A786S | PRAD | 1 |
p.P150H | PAAD | 1 |
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TissGeneCNV for ZNF628 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for ZNF628 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for ZNF628 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for ZNF628 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for ZNF628 |
TissGeneDrug for ZNF628 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for ZNF628 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0002395 | Alzheimer's Disease | 1 | BeFree |