DRUG_ID DRUG_NAME SYNONYMS TARGET TARGET_PATHWAY 1 Erlotinib Tarceva, RG-1415, CP-358774, OSI-774, Ro-508231, R-1415 EGFR EGFR signaling 3 Rapamycin AY-22989, Sirolimus, WY-090217, Torisel, Rapamune MTORC1 PI3K/MTOR signaling 5 Sunitinib Sutent, Sunitinib Malate, SU-11248 PDGFR, KIT, VEGFR, FLT3, RET, CSF1R RTK signaling 6 PHA-665752 PHA665752, PHA 665752 MET RTK signaling 9 MG-132 LLL cpd, MG 132, MG132 Proteasome, CAPN1 Protein stability and degradation 11 Paclitaxel BMS-181339-01, Taxol, Onxol, Paxene, Praxel, Abraxane Microtubule stabiliser Mitosis 17 Cyclopamine SMO Other 29 AZ628 AZ-628, AZ 628 BRAF ERK MAPK signaling 30 Sorafenib Nexavar, 284461-73-0, BAY 43-9006 PDGFR, KIT, VEGFR, RAF RTK signaling 32 Tozasertib MK 0457,MK-0457,MK-045, VX-680 VX 680 VX-68 AURKA, AURKB, AURKC, others Mitosis 34 Imatinib Gleevec, STI-571 ABL, KIT, PDGFR RTK signaling 35 NVP-TAE684 NVP-TAE 684, TAE684, TAE-684 ALK RTK signaling 37 Crizotinib Xalkori, PF2341066, PF-2341066, PF 2341066 MET, ALK, ROS1 RTK signaling 38 Saracatinib AZD0530, AZD-0530, AZ-10353926 ABL, SRC RTK signaling 41 S-Trityl-L-cysteine NSC 83265, Tritylcysteine KIF11 Mitosis 45 Z-LLNle-CHO Z-L-Norleucine-CHO, Gamma-Secretase Inhibitor 1 gamma-secretase Other 51 Dasatinib BMS-354825-03, BMS-354825, Sprycel ABL, SRC, Ephrins, PDGFR, KIT Other 52 GNF-2 KIN001-013 BCR-ABL ABL signaling 53 CGP-60474 KIN001-019, CGP60474, CGP 60474 CDK1,CDK2,CDK5,CDK7,CDK9, PKC Cell cycle 54 CGP-082996 CINK4, KIN001-021 CDK4 Cell cycle 55 A-770041 KIN001-111 LCK, FYN Other, kinases 56 WH-4-023 KIN001-112 SRC, LCK Other, kinases 59 WZ-1-84 KIN001-123 BMX Other, kinases 60 BI-2536 PLK1, PLK2, PLK3 Cell cycle 62 BMS-536924 BMS 536924 IGF1R, IR IGFR signaling 63 BMS-509744 KIN001-127, ITK inhibitor ITK Other 64 CMK KIN001-128 RSK2 ERK MAPK signaling 71 Pyrimethamine Daraprim, Chloridine Dihydrofolate reductase (DHFR) Other 83 JW-7-52-1 NA MTOR PI3K/MTOR signaling 86 A-443654 KIN001-139 AKT1, AKT2, AKT3 PI3K/MTOR signaling 87 GW843682X GW843682X (AN-13) PLK1 Cell cycle 88 Entinostat MS-275 HDAC1, HDAC3 Chromatin histone acetylation 89 Parthenolide HDAC1 Chromatin histone acetylation 91 GSK319347A KIN001-135, IKK-3 inhibitor IKK Other 94 TGX221 TGX-221, Tgx 221 PI3Kbeta PI3K/MTOR signaling 104 Bortezomib PS-341, LDP-341, Velcade Proteasome Protein stability and degradation 106 XMD8-85 ERK5-IN-1 ERK5, BET Other 110 Seliciclib Roscovitine, CYC-202, AL-39256 CDK2, CDK7, CDK9 Cell cycle 111 Salubrinal EIF-2alpha Inhibitor EIF2A Other 119 Lapatinib Tykerb, Tyverb ERBB2, EGFR EGFR signaling 127 GSK269962A GSK 269962A ROCK1, ROCK2 Cytoskeleton 133 Doxorubicin Doxil, Rubex, Adriamycin, Adriablastin, Doxorubicine Anthracycline DNA replication 134 Etoposide Etopophos, Vepesid, Eposin, VP-16 TOP2 DNA replication 135 Gemcitabine Gemzar, LY-188011 Pyrimidine antimetabolite DNA replication 136 Mitomycin-C Mytozytrex, NSC-26980, MMC, Mitosol, Mitozytrex DNA crosslinker DNA replication 140 Vinorelbine vinorelbine tartrate, Navelbine, Exelbine Microtubule destabiliser Mitosis 147 NSC-87877 NSC 87877 SHP-1 (PTPN6), SHP-2 (PTPN11) Other 150 Bicalutamide ICI-176334, Casodex, Cosudex, ICI 176334 AR Hormone-related 151 QS11 944328-88-5 ARFGAP1 Other 152 CP466722 CP-466722, CP 466722, 1080622-86-1 ATM Genome integrity 153 Midostaurin PKC412, benzoylstaurosporine, CGP-41251 PKC, PPK, FLT1, c-FGR, others Other 154 CHIR-99021 CT 99021, CHIR99021, CHIR 99021 GSK3A, GSK3B WNT signaling 155 Ponatinib AP24534, AP-24534, KIN001-192, Iclusig ABL, PDGFRA, VEGFR2, FGFR1, SRC, TIE2, FLT3 RTK signaling 156 AZD6482 AZD 6482, AZD-6482, AK-55409 PI3Kbeta PI3K/MTOR signaling 157 JNK-9L KIN001-204, JNK inhibitor 9l JNK2, JNK3 JNK and p38 signaling 158 PF-562271 PF-00562271 FAK, FAK2 Cytoskeleton 159 HG6-64-1 KIN001-206 BRAF ERK MAPK signaling 163 JQ1 JQ-1, (+)-JQ-1 BRD2, BRD3, BRD4, BRDT Chromatin other 164 JQ12 HDAC1, HDAC2 Chromatin histone acetylation 165 DMOG Dimethyloxalylglcine HIF-PH Metabolism 166 FTI-277 Farnesyl-transferase (FNTA) Other 167 OSU-03012 AR-12, OSU 03012, OSU03012, PDK1 inhibitor AR-12 PDK1 (PDPK1) Other, kinases 170 Shikonin Anchusin not defined Other 171 AKT-inhibitor-VIII Akti-1/2 AKT1, AKT2, AKT3 PI3K/MTOR signaling 172 Embelin Emberine, Embelic acid XIAP Apoptosis regulation 173 FH535 PPARgamma, PPARdelta WNT signaling 175 PAC-1 GTPL5238 Procaspase-3, Procaspase-7 Apoptosis regulation 176 IPA-3 IPA 3 PAK1 Cytoskeleton 177 GSK650394 GSK-650394, GSK 650394 SGK2, SGK3 Other 178 BAY-61-3606 Syk Inhibitor, BAY-613606 SYK Other, kinases 179 5-Fluorouracil 5-FU Antimetabolite (DNA & RNA) Other 180 Thapsigargin Octanoic acid SERCA Other 182 Obatoclax-Mesylate GX15-070MS, Obatoclax, GX15-070 BCL2, BCL-XL, BCL-W, MCL1 Apoptosis regulation 184 BMS-754807 BMS754807, BMS 754807 IGF1R, IR IGFR signaling 185 Linsitinib OSI-906, ASP-7487 IGF1R IGFR signaling 186 Bexarotene LG-100069, Targretin, Targret, Targrexin, Targretyn, Bexarotenum Retinioic X receptor (RXR) agonist Other 190 Bleomycin dsDNA break induction DNA replication 192 LFM-A13 DDE-28 BTK Other, kinases 193 GW-2580 GX2580, CFMS receptor tyrosine kinase inhibitor CSF1R RTK signaling 194 Luminespib AUY922, VER-52296,NVP-AUY922, AUY HSP90 Protein stability and degradation 196 Phenformin DBI Biguanide agent Other 197 Bryostatin-1 Bryostatin PKC Other, kinases 199 Pazopanib Votrient CSF1R, KIT, PDGFRA, PDGFRB RTK signaling 200 Dacinostat NVP-LAQ824, LAQ824 HDAC1 Chromatin histone acetylation 201 Epothilone-B Patupilone, EpoB, EPO906, GNF-PF-193 Microtubule stabiliser Mitosis 202 GSK1904529A GSK-1904529A, GSK 1904529A IGF1R, IR IGFR signaling 203 BMS-345541 BMS345541, IKK Inhibitor 3 IKK1, IKK2 Other, kinases 204 Tipifarnib Zarnestra Farnesyl-transferase (FNTA) Other 205 Avagacestat BMS-708163, BMS 708163 Amyloid beta20, Amyloid beta40 Other 206 Ruxolitinib INCB-18424, Ruxolitinib Phosphate, Jakafi JAK1, JAK2 Other, kinases 207 AS601245 JNK1, JNK2, JNK2 JNK and p38 signaling 208 Ispinesib-Mesylate SB-715992 KSP Mitosis 211 TL-2-105 not defined Unclassified 219 AT-7519 AT7519 CDK1, CDK2, CDK4, CDK6, CDK9 Cell cycle 221 TAK-715 KIN001-201, TAK 715 p38alpha, p38beta JNK and p38 signaling 222 BX-912 PDK1 (PDPK1) PI3K/MTOR signaling 223 ZSTK474 KIN001-167, ZSTK-474, ZSTK 474 PI3K (class 1) PI3K/MTOR signaling 224 AS605240 KIN001-173, AS-605240 PI3Kgamma PI3K/MTOR signaling 225 Genentech-Cpd-10 AURKA, AURKB Mitosis 226 GSK1070916 GSK-1070916 AURKA, AURKC Mitosis 228 AKT inhibitor VIII Akti-1/2, KIN001-102 AKT1, AKT2, AKT3 PI3K/MTOR signaling 229 Enzastaurin LY317615 PKCB Other, kinases 230 GSK429286A ROCK1, ROCK2 Cytoskeleton 231 FMK KIN001-242 RSK Other, kinases 235 QL-XII-47 BTK, BMX Other, kinases 238 Idelalisib CAL-101, Zydelig PI3Kdelta PI3K/MTOR signaling 245 UNC0638 UNC-0638, UNC 0683 G9a and GLP methyltransferases Chromatin histone methylation 249 Cabozantinib BMS-907351, XL-184, Cometriq VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, TIE2,AXL Other, kinases 252 WZ3105 SRC, ROCK2, NTRK2, FLT3, IRAK1, others Other 253 XMD14-99 ALK, CDK7, LTK, others Other 254 Quizartinib AC220, AC 220, AC-220, Asp-2689 FLT3 RTK signaling 255 CP724714 CP-724714 ERBB2 EGFR signaling 256 JW-7-24-1 LCK Other, kinases 257 NPK76-II-72-1 PLK3 Cell cycle 258 STF-62247 STF62247 Autophagy inducer Other 260 NG-25 NG25 TAK1, MAP4K2 Other, kinases 261 TL-1-85 TAK Other, kinases 262 VX-11e VX11e, VX11e ERK2 ERK MAPK signaling 263 FR-180204 FR 180204, FR180204, ERK Inhibitor II ERK1, ERK2 ERK MAPK signaling 265 Tubastatin-A HDAC1, HDAC6, HDAC8 Chromatin histone acetylation 266 Zibotentan ZD4054, ZD-4054 Endothelin-1 receptor (EDNRA) Other 268 Sepantronium-bromide YM155, YM-155, YM 155 BIRC5 Apoptosis regulation 269 NSC-207895 XI-006, NSC207895 MDM4 p53 pathway 271 VNLG-124 HDAC inhibitor XV HDAC,RAR Chromatin histone acetylation 272 AR-42 HDAC-42, AR 42, AR42 HDAC1 Chromatin histone acetylation 273 CUDC-101 CUDC 101 HDAC1-10, EGFR, ERBB2 Other 274 Belinostat PXD101, PXD-101 HDAC1 Chromatin histone acetylation 275 I-BET-762 GSK525762A BRD2, BRD3, BRD4 Chromatin other 276 CAY10603 HDAC1, HDAC6 Chromatin histone acetylation 277 Linifanib ABT-869, ABT 869 VEGFR1, VEGFR2, VEGFR3, CSF1R, FLT3, KIT RTK signaling 279 BIX02189 BIX 02189 MEK5, ERK5 ERK MAPK signaling 281 Alectinib CH5424802, CH 542802, Alecensa ALK RTK signaling 282 Pelitinib EKB-569, EKB 569 EGFR EGFR signaling 283 Omipalisib GSK2126458, GSK-2126458, EX-8678, GSK458 PI3K (class 1), MTORC1, MTORC2 PI3K/MTOR signaling 286 KIN001-236 Angiopoietin-1 receptor Other 287 KIN001-244 PDK1 inhibitor 7 PDK1 (PDPK1) Other, kinases 288 WHI-P97 AC1L1GQE, KIN001-055 JAK3 Other, kinases 290 KIN001-260 Bayer IKKb inhibitor, ACHP IKKB Other 291 KIN001-266 MAP3K8 Other, kinases 292 Masitinib AB1010, Masivet KIT, PDGFRA, PDGFRB Other, kinases 293 Amuvatinib MP470, MP 470, MP-470 KIT, PDGFRA, FLT3 Other, kinases 294 MPS-1-IN-1 MPS1 Mitosis 295 NVP-BHG712 BHG712 EPHB4 Other 298 OSI-930 OSI 930 OSI930 KIT RTK signaling 299 OSI-027 A-1065-5 MTORC1, MTORC2 PI3K/MTOR signaling 300 CX-5461 CX5461, CX 5461 RNA Polymerase 1 Other 301 PHA-793887 PHA793887, PHA 793887 CDK2, CDK7, CDK5 Cell cycle 302 PI-103 PI-103, PI103, PI 103 PI3Kalpha, DAPK3, CLK4, PIM3, HIPK2 PI3K/MTOR signaling 303 PIK-93 PIK 93, PIK93 PI3Kgamma PI3K/MTOR signaling 304 SB52334 SB-52334, SB 52334 ALK5 RTK signaling 305 TPCA-1 IKK2 Other, kinases 306 Fedratinib TG101348, TG-101348, SAR302503, SAR-302503 JAK2 Other, kinases 308 Foretinib GSK1363089, XL-880, EXEL-2880, GSK089 MET, KDR, TIE2, VEGFR3/FLT4, RON, PDGFR, FGFR1, EGFR RTK signaling 309 Y-39983 ROCK Cytoskeleton 310 YM201636 YM-201636, YM 201636 PYKFYVE Other 312 Tivozanib AV-951, AV 951, KRN-951, KIL8951, ASP-4130 VEGFR1, VEGFR2, VEGFR3 RTK signaling 326 GSK690693 GSK 690693, GSK-690693 AKT1, AKT2, AKT3 PI3K/MTOR signaling 328 SNX-2112 SNX 2112 HSP90 Protein stability and degradation 329 QL-XI-92 DDR1 Other 330 XMD13-2 RIPK1 Apoptosis regulation 331 QL-X-138 BTK Other, kinases 332 XMD15-27 CAMK2 Other, kinases 333 T0901317 TO-901317, TO901317 LXR, FXR Other 341 Selisistat EX-527, EX 527 SIRT1 Chromatin histone acetylation 344 THZ-2-49 CDK9 Cell cycle 345 KIN001-270 CDK9 inhibitor, CDK9-IN-1 CDK9 Cell cycle 346 THZ-2-102-1 CDK7 Cell cycle 1001 AICA-Ribonucleotide AICAR, N1-(b-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide AMPK agonist Metabolism 1003 Camptothecin Camptothecine, (+)-Camptothecin TOP1 DNA replication 1004 Vinblastine Velban Microtubule destabiliser Mitosis 1005 Cisplatin cis-Diammineplatinum(II) dichloride, Platinol, CIS-DDP DNA crosslinker DNA replication 1006 Cytarabine Ara-Cytidine, Arabinosyl Cytosine, U-19920 Antimetabolite DNA replication 1007 Docetaxel RP-56976, Taxotere Microtubule stabiliser Mitosis 1008 Methotrexate Abitrexate, Amethopterin, Rheumatrex, Trexall, Folex Antimetabolite DNA replication 1009 Tretinoin ATRA, Vesanoid, Renova, Atralin, Tretin-X, Avita Retinoic acid Other 1010 Gefitinib ZD-1839, Iressa EGFR EGFR signaling 1011 Navitoclax ABT-263, ABT263, ABT 263 BCL2, BCL-XL, BCL-W Apoptosis regulation 1012 Vorinostat Zolinza, SAHA, suberanilohydroxamic acid, suberoylanilide hydroxamic acid, MK-0683 HDAC inhibitor Class I, IIa, IIb, IV Chromatin histone acetylation 1013 Nilotinib Tasigna, AMN 107 ABL ABL signaling 1014 Refametinib RDEA119, BAY-86-9766, BAY 869766 MEK1, MEK2 ERK MAPK signaling 1015 CI-1040 CI 1040, PD-18435, PD-184352, 212631-79-3 MEK1, MEK2 ERK MAPK signaling 1016 Temsirolimus CCI-779, Torisel MTOR PI3K/MTOR signaling 1017 Olaparib AZD2281, KU0059436, Lynparza PARP1, PARP2 Genome integrity 1018 Veliparib ABT-888, ABT888, ABT 888 PARP1, PARP2 Genome integrity 1019 Bosutinib SKI-606, Bosulif SRC, ABL, TEC Other, kinases 1020 Lenalidomide CDC-501, CC-5013, Revlimid CRBN Protein stability and degradation 1021 Axitinib AG-13736, Inlyta PDGFR, KIT, VEGFR RTK signaling 1022 AZD7762 AZD-7762, AZD 7762 CHEK1, CHEK2 Cell cycle 1023 GW441756 GW 441756 NTRK1 RTK signaling 1024 Lestaurtinib CEP-701, SP-924, SPM-924, A-154475, KT-555 FLT3, JAK2, NTRK1, NTRK2, NTRK3 Other, kinases 1025 SB216763 SB-216763, SB 216763 GSK3A, GSK3B WNT signaling 1026 Tanespimycin 17-AAG, BMS-722782 HSP90 Protein stability and degradation 1028 VX-702 VX702, VX 702 p38 JNK and p38 signaling 1029 Motesanib AMG-706, AMG 706, AMG706 VEGFR, RET, KIT, PDGFR RTK signaling 1030 KU-55933 KU55933 ATM Genome integrity 1031 Elesclomol STA-4783 HSP90 Protein stability and degradation 1032 Afatinib BIBW2992, Tovok, Gilotrif ERBB2, EGFR EGFR signaling 1033 Vismodegib GDC0449, Erivedge SMO Other 1036 PLX-4720 PLX4720, PLX 4720 BRAF ERK MAPK signaling 1037 BX795 BX-795 TBK1, PDK1 (PDPK1), IKK, AURKB, AURKC Other 1038 NU7441 KU-57788, NU-7432, NU-7741 DNAPK Genome integrity 1039 SL0101 SL-0101, SL 0101-1 RSK, AURKB, PIM1, PIM3 Other 1042 Doramapimod BIRB-796, BIRB 796 p38, JNK2 JNK and p38 signaling 1043 JNK-Inhibitor-VIII JNK JNK and p38 signaling 1046 Wee1-Inhibitor 681640, Wee1 Inhibitor WEE1, CHEK1 Cell cycle 1047 Nutlin-3a (-) MDM2 p53 pathway 1049 PD173074 PD-173074, PD 173074 FGFR1, FGFR3 RTK signaling 1050 ZM447439 ZM-447439, ZM 447439 AURKA, AURKB Mitosis 1052 RO-3306 CDK1 Cell cycle 1053 MK-2206 MK 2206, MK2206 AKT1, AKT2 PI3K/MTOR signaling 1054 Palbociclib PD0332991, PD-0332991, PF-00080665-73 CDK4, CDK6 Cell cycle 1057 Dactolisib NVP-BEZ235, BEZ235 PI3K (Class 1), MTORC1, MTORC2 PI3K/MTOR signaling 1058 Pictilisib GDC-0941, GDC0941, RG-7621 PI3K (class 1) PI3K/MTOR signaling 1059 AZD8055 AZD-8055 MTORC1, MTORC2 PI3K/MTOR signaling 1060 PD0325901 PD-0325901, PD 0325901 MEK1, MEK2 ERK MAPK signaling 1061 SB590885 SB-590885 BRAF ERK MAPK signaling 1062 Selumetinib AZD6244, AZD-6244, ARRY-886 MEK1, MEK2 ERK MAPK signaling 1066 AZD6482 AZD 6482, AZD-6482, AK-55409 PI3Kbeta PI3K/MTOR signaling 1067 CCT007093 PPM1D Other 1069 EHT-1864 EHT 1864 RAC1, RAC2, RAC3 Cytoskeleton 1072 Avagacestat BMS-708163, BMS 708163 Amyloid beta20, Amyloid beta40 Other 1091 BMS-536924 BMS 536924 IGF1R, IR Unclassified 1114 Cetuximab Erbitux, IMC-C225, C225, IMC-225, L01XC06 EGFR EGFR signaling 1129 PF-4708671 PF 4708671, PF4708671 S6K1 PI3K/MTOR signaling 1133 Serdemetan JNJ-26854165 MDM2 p53 pathway 1142 HG-5-113-01 LOK, LTK, TRCB, ABL(T315I) Other 1143 HG-5-88-01 EGFR, ADCK4 Other, kinases 1149 TW-37 TW37, TW-37 BCL2, BCL-XL, MCL1 Apoptosis regulation 1158 XMD11-85h BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1 Other 1161 ZG-10 JNK1 JNK and p38 signaling 1164 XMD8-92 XMD 8-92 MAPK7 Other, kinases 1166 QL-VIII-58 MTOR, ATR Other 1170 CCT-018159 CCT018159, CCT 018159 HSP90 Protein stability and degradation 1175 Rucaparib PF-01367338, AG-014699, AG-14447, AG-14699 PARP1, PARP2 Genome integrity 1192 GSK269962A GSK 269962A ROCK1, ROCK2 Cytoskeleton 1194 SB505124 SB 505124, SB505124 ALK4, ALK5 RTK signaling 1199 Tamoxifen Nolvadex, Soltamox, Zynoplex, ICI-46474, Kessar ESR1 Hormone-related 1203 QL-XII-61 BMX, BTK Other, kinases 1218 JQ1 JQ-1, (+)-JQ-1 BRD2, BRD3, BRD4, BRDT Chromatin other 1219 PFI-1 BRD4 Chromatin other 1230 IOX2 IOX-2, IOX 2, AK176060 EGLN1 Other 1236 UNC0638 UNC-0638, UNC 0683 G9a and GLP methyltransferases Chromatin histone methylation 1239 YK-4-279 YK 4-279 RNA helicase A Other 1241 CHIR-99021 CT 99021, CHIR99021, CHIR 99021 GSK3A, GSK3B WNT signaling 1242 (5Z)-7-Oxozeaenol 5Z-7-Oxozeaenol, LL-Z1640-2 TAK1 Other, kinases 1243 Piperlongumine Piplartine Induces reactive oxygen species Other 1248 Daporinad APO866, FK866, FK866 NAMPT Metabolism 1259 Talazoparib BMN-673, BMN 973 PARP1, PARP2 Genome integrity 1261 rTRAIL TRAIL receptor agonist Apoptosis regulation 1262 UNC1215 UNC-1215 L3MBTL3 Chromatin other 1264 SGC0946 DOT1L Chromatin histone methylation 1266 ICL1100013 N-myristoyltransferase 1/2 Other 1268 XAV939 NVP-XAV939, XAV-939, XAV 939 TNKS1, TNKS2 WNT signaling 1371 PLX-4720 PLX4720, PLX 4720 BRAF ERK MAPK signaling 1372 Trametinib GSK1120212, Mekinist MEK1, MEK2 ERK MAPK signaling 1373 Dabrafenib GSK2118436, Tafinlar BRAF ERK MAPK signaling 1375 Temozolomide Temodar, Temodal, M-39831, SCH 52365 DNA alkylating agent DNA replication 1377 Afatinib BIBW2992, Tovok, Gilotrif ERBB2, EGFR EGFR signaling 1378 Bleomycin (50 uM) dsDNA break induction DNA replication 1494 SN-38 7-Ethyl-10-Hydroxy-Camptothecin, SN 38 TOP1 DNA replication 1495 Olaparib AZD2281, KU0059436, Lynparza PARP1, PARP2 Genome integrity 1498 Selumetinib AZD6244, AZD-6244, ARRY-886 MEK1, MEK2 ERK MAPK signaling 1502 Bicalutamide ICI-176334, Casodex, Cosudex, ICI 176334 AR Hormone-related 1526 Refametinib RDEA119, BAY-86-9766, BAY 869766 MEK1, MEK2 ERK MAPK signaling 1527 Pictilisib GDC-0941, GDC0941, RG-7621 PI3K (class 1) PI3K/MTOR signaling 1529 Pevonedistat MLN4924, MLN 4924, MLN-4924 NAE Other 1530 PFI-3 BDF00016096 SMARCA2, SMARCA4, PB1 Other