17-AAG AEW541 AZD0530 AZD6244 Erlotinib Irinotecan L-685458 Lapatinib LBW242 Nilotinib Nutlin-3 Paclitaxel Panobinostat PD-0325901 PD-0332991 PF2341066 PHA-665752 PLX4720 RAF265 Sorafenib TAE684 TKI258 Topotecan ZD-6474 Pt1.DP1 3.81774334928084 1.32333584250959 1.03431363470006 2.77475728555747 0.698385900989314 2.37575543233894 0.524536988944545 0.73634731078039 0.880645723517131 0.818375185208668 0.579488604539682 4.32626538551431 4.64887808234702 4.4356089587133 0.89802315032364 0.902067755096725 0.535276123148678 1.17647423180503 2.39190201657808 0.689479687167394 1.43294728952599 1.41915131351207 2.44155736776727 1.58439236889048 Pt1.baseline 3.71983004556973 1.27239708512216 0.864925212577235 2.46933959741587 0.647903579566634 2.28070043732866 0.474702702072156 0.674638699966019 0.853159888326769 0.595173574547192 0.633939665465294 3.81851538444711 4.3713377711776 3.9425650204943 0.749890405714185 0.890630257977184 0.448039281011661 1.2026874438957 2.23609067962289 0.604677000850976 1.3428353838857 1.32802592221391 2.30579100524231 1.73583427924361 Pt2.DP1 2.84589720203926 1.21632737508859 0.994482492845466 2.16866203623209 0.52808918073395 1.7350974195222 0.514416146619234 0.680940517328809 0.822822797795768 0.82443528763132 0.618433514012466 3.80133714529425 4.44973386177952 3.43845849861579 0.761736198045365 0.983638135078146 0.622110555600257 1.14744331770701 1.79235007835366 0.573993134186399 0.728186441488922 1.23131602147934 2.13429323272036 1.62371331083235 Pt2.DP2 3.18642118764023 1.13556354800477 1.00360538470613 2.58292455775538 0.600758806961634 2.01490406726772 0.502866054633628 0.508524389254535 0.889919525032592 0.973468468729343 0.643884142099617 4.14922471981204 4.47486269816455 3.9782010511018 0.675467542032123 0.962430921521017 0.686883166752438 1.24619235821494 1.99871312071743 0.650227254829749 0.809864856567825 1.2641033263203 2.37657458518356 1.59910523066014 Pt2.baseline 2.86011156491943 1.21964733979801 1.0493683286064 2.35697197124927 0.584070363717085 1.99367224110505 0.578373915382048 0.610557795462293 0.939003443185038 0.960325207847926 0.643440142873906 3.86884658813417 4.64170989751959 3.5945235034577 0.846945734777999 1.00344050787539 0.654785319921063 1.15828305689763 2.06336416590334 0.650225247707768 0.856708536831251 1.27690057400014 2.29390320181175 1.57286493536069 Pt3.DP1 3.45867286051774 0.985133413273208 1.00906712919857 2.94114278288419 0.487674564504801 2.91106957803636 0.45782641526102 0.511961413535723 0.751781130690138 0.60364789447707 0.474545827146702 4.5871406000736 4.62108959629591 4.07075579917503 0.581416636932162 0.84882917041058 0.716561536919232 1.50946488359316 2.39538798688626 0.694203329628542 1.34678240382595 1.26680136309956 2.73651466783542 1.21182163936098 Pt3.DP2 3.94630658915735 0.980615106420089 1.06236119083635 2.86956875137449 0.692001969414102 3.38368268752674 0.455794555763113 0.550486719580511 0.879249264516287 0.561702433731956 0.528231770255901 4.85491746292914 4.69569143640996 3.87815593690032 0.65417361171035 0.870793936239667 0.775138301872284 1.54416702256632 2.50716699026349 0.690762299717737 1.48397771126856 1.33929160925777 3.00681706360279 1.38155417777118 Pt3.DP3 3.90053067687475 0.973296984395365 1.09753338626102 2.86764741903812 0.889189538791403 2.93106348969356 0.428980571676808 0.75228632059103 0.81400364510344 0.613722794200845 0.515569449596293 4.5777545224408 4.58258017561018 3.86897257996814 0.483505720404232 0.810252971758205 0.750253962416088 1.41488343057689 2.41806856996361 0.680748314690869 1.43619093938155 1.22443641198216 2.62190534696023 1.72676773606018 Pt3.baseline 3.56094441366919 1.0628593631751 1.06945272752486 2.70764001051366 0.887941283941353 3.04023109534825 0.34074965350399 0.887945835332255 0.729450898299004 0.508139454572912 0.492251855616994 4.54390166714847 4.6293544567548 3.88000737896768 0.541947731318129 0.743554654005087 0.620441597746438 1.44909094917581 2.36142464735935 0.657123922223865 1.47021302295362 1.3510537980644 2.78311515526309 1.55050420714264 Pt4.DP1 3.80098300652791 1.16481367670212 1.18223742715695 2.43723101154659 0.754670964558927 2.69698511946644 0.692903269616999 0.498807985332658 0.795112002337113 1.06331387512495 0.637151833068631 4.74603734794508 4.60463027584324 3.13180629334114 0.624918895268947 0.961812760598625 0.881941939360711 1.01523786866429 2.12345377350692 0.75586173378311 1.36880121424196 1.44552464957612 3.04386991509527 1.76344573843967 Pt4.baseline 3.79953267059544 1.19856759684925 1.17793560308489 2.46977351653687 0.945265133168581 2.84059094965701 0.646333854631428 0.677093036793876 0.803028917954317 0.816470131603715 0.601072408366619 5.08433043566187 4.52097042649499 3.22770249022022 0.588799742360474 0.954945924685451 0.709728905945291 0.869701567266706 2.25654416590036 0.741838030667685 1.31701519120088 1.44060604384942 2.7854765396045 1.84352680519837 Pt5.DP1 3.43098037324286 1.22412881025666 1.08191805396402 2.82999770184461 1.07735679724474 2.16494283205641 0.479340197012793 1.20106731175054 0.805814205298216 0.843175842301608 0.605764505035206 4.41327088153052 4.63231576718767 4.25581568253343 0.606023831568972 0.733184049676137 0.684418991165068 1.36241031905814 2.25624946112231 0.684031031811831 1.31665626217859 1.35577948739183 2.14491682446215 2.22778888489582 Pt5.DP2 3.17267256658338 1.17463624307381 1.12691024861219 2.59200803552689 1.22412553712923 2.11549471994679 0.469968885922873 1.3690169312066 0.766810774429638 0.76804996874052 0.576219152046998 4.40441424639887 4.59744625379869 3.84405326933864 0.504139143297496 0.67922285458636 0.68082346285575 1.21149207002335 2.14304328665495 0.671984542211179 1.12736560638348 1.2549888774558 2.12267681754907 2.33559159725936 Pt5.DP3 3.65930017258849 1.10348099544549 1.08848319476903 2.80563196803301 0.999146982464532 2.16798623770814 0.500049242166422 1.09334427131466 0.810436547827851 0.864151013753575 0.628433003010674 4.23165400825998 4.69192543265742 4.17251505592124 0.602293189892457 0.766809293954912 0.692854034510448 1.39301393621509 2.22374742939092 0.661583418460034 1.11307490632174 1.26211086002091 2.2995320886071 2.23422383414609 Pt5.baseline 3.67788388515583 1.15715872750237 1.04749586537068 2.86106541726944 0.911337780540152 2.07007033780484 0.567494407984017 1.02173068205658 0.821203064838131 0.920647866209932 0.645248543067878 4.24999881997478 4.66969624980862 4.3049889953722 0.701396840228025 0.822937430136272 0.752240284229283 1.35516852848783 2.33980081339561 0.746013452045197 1.23807088973093 1.33805603659062 2.3818400874923 2.23709525975962 Pt6.DP1 3.34024781683101 1.0937137744488 1.26848285618525 2.40559648966522 1.35781730620294 2.38854462636471 0.711898957587224 1.49688731127896 0.853372621718722 1.03131564666923 0.682753753729185 4.91853248804916 4.86050905649943 3.17008906350564 0.798370672586047 0.903913899209438 1.11121072328321 1.26641530039606 2.3756814115785 0.935286633007542 1.08799738968791 1.72428965048247 2.81073402569633 2.50990571861419 Pt6.DP2 3.67383243923086 0.959945479769757 1.06915445637497 2.52572313043942 0.79422893006005 2.14388812050091 0.638564622209144 0.729563743474118 0.873001536072312 0.987674768319815 0.640605367331016 4.6075136331871 4.58667178113875 3.35014250724269 0.641886200809281 0.945503570492508 0.946228916149122 1.50936569163624 2.50615223668785 0.885523999763794 0.782948425523227 1.47259055013462 2.41380352344428 1.77166133370536 Pt6.baseline 4.07685314949399 1.03044263853453 0.972186292934204 2.68521733810302 0.656529187056411 2.46274130431107 0.529493148817823 0.623456864858731 0.790740365151227 0.871980970657914 0.593571160851744 5.06564806347457 4.55330692836506 3.93912097841964 0.464060616536837 0.849061429707189 0.695790330172196 1.49249116670367 2.29881873248454 0.659788237697517 0.915378461931126 1.3674308483586 2.85186225963146 1.39350201432657 Pt8.DP1 3.22034548464549 1.10826879938013 1.1438118046651 2.28806623145862 0.898777437090531 1.97763335703573 0.633252052050352 0.804110325482741 0.790573087572263 0.880243801940409 0.590259457846987 3.85104538732819 4.37082844069631 3.05960331585613 0.60414355151977 0.797844086789426 0.757415001041707 0.990586127112127 2.19231783459022 0.643381843218932 0.926607243556358 1.28181962377482 2.17694531482019 1.82306102509906 Pt8.DP2 3.41539823638295 1.18331431512428 1.3702478429194 2.26089941901942 1.38432945527309 2.69808288925766 0.595779708286371 1.33766798193476 0.727353715695739 0.970556452622007 0.574144377314764 5.46512448788748 4.68111250040243 3.22045611053945 0.522741264525147 0.698194529370574 0.663691447048041 1.10707290081342 2.1307325412655 0.686537873493376 1.25056259773695 1.36237538368677 2.62497847461672 2.44030150230645 Pt8.DP3 3.20189680535772 1.23489506863671 0.928155302165269 2.05617537496519 0.68139841264408 2.02141781704853 0.600872456707501 0.710076573895414 0.755351275861912 0.933732373062826 0.569112176955916 4.21736340472727 4.58672480558705 3.19579731762591 0.827392024168753 0.781267067092465 0.466583051545631 1.05416421376202 2.10445532066374 0.620117422663101 1.43617233878523 1.31453625898803 2.3124930728777 1.72598800420074 Pt8.baseline 3.34542052935833 1.13942228848924 1.16601622559242 2.62175632210803 1.17641684929415 2.00085047562851 0.46932859921527 1.07791321215723 0.749139723785057 0.674971040778424 0.581337687748606 4.3996213270821 4.57323169083208 3.85186282415236 0.463719173706664 0.7264467859305 0.543333035921504 0.940840583613574 2.2215067042737 0.621403798457067 1.04387270419931 1.25354180660918 2.05826172673606 2.18380664549676 Pt9.DP1 3.8343565004911 1.10574627198794 1.18027064080184 2.79128302547287 0.638331622263534 2.6633604393386 0.702136633776592 0.450109114825625 0.727858273454369 1.05808821152764 0.572837955579017 5.3696593006826 4.85892489818127 3.80098189659196 0.806517201553212 0.95781590097131 0.763139488165435 1.46611522815794 2.14629976998244 0.656178549502247 1.40316629009944 1.476975544647 2.91594484200819 1.5815168630298 Pt9.DP2 3.39159798100678 1.23310660555243 1.04801020820254 2.52075707922055 0.571607064886757 2.65419420187177 0.620750222908568 0.561160372939078 0.677349576996855 1.0221012599227 0.570575852405348 5.44469669265072 4.97743292582749 3.63951732573324 0.760058517423859 0.991763354605966 0.545695393202454 1.50120150737558 1.86842056393339 0.555203227780488 1.5627346088473 1.34035712007059 2.844246493747 1.65405702597924 Pt9.baseline 3.12311033020132 1.20325439751607 1.08260462261558 2.79315884499411 0.499432325711288 2.80386511634883 0.559214119513127 0.562172713606548 0.707441986951546 0.89904563528061 0.580926974129816 5.03367359903015 4.94479227058962 3.81356867422617 0.896884601864167 0.979377675806397 0.678280543520164 1.48836874485041 2.12076042226165 0.480875622642497 1.40458177568483 1.32404683363887 2.89491658129881 1.55145228729996 Pt10.DP1 3.47371701650102 1.10062639324388 1.17318026060428 2.69462978236268 1.19070861841894 1.96360690896544 0.543608311423145 1.32245727430601 0.763930410117056 0.75825693359034 0.641623903605348 4.30630225553311 4.49038332701449 3.80172726868997 0.800337752081317 0.709405564594766 0.694751161363845 0.93777094778864 2.25525978338536 0.758488783278782 1.30927152730151 1.42235070904901 2.11429830123662 2.35914373563539 Pt10.DP2 2.95186037922816 1.01514058234217 1.09383733998718 2.76604600735523 0.917170519123876 2.07494850984259 0.355920766132978 0.882634099725116 0.74557084665572 0.684755785359517 0.577102275751384 4.04940866045357 4.70509847158417 4.13391788333778 0.616653321088883 0.654044436276463 0.48178682289819 1.19651746411559 2.28263708085226 0.649846213550498 1.11834706361239 1.22193281951332 1.71022156007361 1.69915767279707 Pt10.DP3 2.98700564882162 1.1046265332492 1.06751647741445 2.47637620243909 0.809418020531145 2.65164396307563 0.598476310156819 0.733414178966455 0.712256788269842 0.580856181410617 0.622306500538196 5.16432308471832 4.77991261036003 3.55016389452484 0.958700100453767 0.800957439666315 0.51748386883059 1.08524211645616 2.18053482556803 0.529311155892338 1.37525483095084 1.41997689066716 2.67361919841334 1.75583699240183 Pt10.DP4 3.21050332405454 0.932094330425944 1.12442457501534 2.80589432035437 1.00868301257344 1.94609245334 0.551167038617409 1.05280620260964 0.789857803894067 0.85487042306137 0.656496740162866 4.61213000746658 4.84295993593723 4.05960220870971 0.710781405250956 0.785231522016034 0.735520838303281 1.13552123646973 2.3601858138352 0.773088140556173 1.2165606096941 1.34446050692108 2.03150028830869 2.02904538801822 Pt10.DP5 3.44299031153408 1.04978005330952 1.24464496022708 2.55458001092096 1.27000235164508 2.02305759300965 0.58185082093172 1.32997593860451 0.770906707113432 0.86010412619973 0.642326999687952 4.64783405908148 4.79216369954095 3.52412072778129 0.838106237146483 0.729875661801921 0.835135991722227 0.923801448080616 2.24256368628003 0.733495298311668 1.17725634583197 1.49648522146766 2.30644121017494 2.46893321584664 Pt10.DP6 3.3898163168205 1.00655479756371 1.18790435850382 2.51469357138185 1.19032819015253 1.90807611301343 0.582357488110093 1.2465502048093 0.763837235922315 0.755472081811573 0.655794868684101 4.55993321979604 4.76440257308526 3.49805228469404 0.786286293767289 0.710286471396217 0.840630709539224 0.895628716376399 2.28430642341381 0.761106355610295 1.11765384865497 1.49361263710881 2.29420850469352 2.42928463333831 Pt10.DP7 3.39200951986045 1.01763215937546 1.22758997911702 2.42061425192751 1.25293643764552 2.04189842947447 0.702037827176606 1.28060355029261 0.766945562691015 0.855342669765447 0.667693079231613 4.52971839083614 4.80496911981209 3.20551255108307 0.866164387939099 0.777418148098784 0.929568542584597 0.730074566344516 2.255387595373 0.813452738080451 1.13742981008062 1.54669125584107 2.44424038937569 2.61207339740993 Pt10.DP8 2.98857074752323 1.1118340625958 1.06868168753917 2.27259623485024 0.829491316802808 2.21243568745433 0.627756902264153 0.546062923716082 0.833505736709224 0.749596886781327 0.635381039702415 5.33334757341566 4.88902210138446 3.21085874208566 0.923659081299599 0.849976729198883 0.628316061722175 0.965038548462852 2.39244245954533 0.797042367649832 1.25722973194502 1.60819530498515 2.67760814361357 1.59697403700189 Pt10.DP9 3.44358954469131 1.10177901553854 1.09378451448934 2.39729733738827 0.714740798306588 2.2359833089366 0.645353147585428 0.532406463770274 0.840385506101401 0.836799893424741 0.627789232199254 5.26601849133096 4.84081672070059 3.23860813774547 0.834660611164484 0.868961269830403 0.692958606637539 1.14351146125759 2.45781224587014 0.8020958144442 1.24287313110258 1.64028056348766 2.73876361113098 1.53184586378411 Pt10.baseline 3.44868706391482 1.06735268476504 1.15514353669191 2.46805755292305 1.16067364388008 1.96346367083695 0.550641005962513 1.28139895068099 0.759164741151974 0.79423431284879 0.667946538809763 4.54954259331442 4.51905151852314 3.42400601603907 0.66733745751869 0.692332869739905 0.683894341570505 0.728996036481448 2.32176468917233 0.714591289686097 1.24065728667384 1.52420306763753 2.28032032119601 2.42577116130305 Pt15.DP1 3.00449044792095 1.16961133411491 1.02758468181938 2.75494001460726 0.586947364547975 2.29663204201478 0.525900368366791 0.674818835780748 0.802191649381292 0.84206699438209 0.651799496532555 4.29865218722436 4.53305259148946 4.10869222867394 0.725816693696411 0.780737774256254 0.620106092002322 1.38402611882819 2.3723202135532 0.772013313748802 1.21645622858643 1.27852314299056 2.32698616990242 1.50536653655549 Pt15.DP2 3.48673950265717 1.26128420096826 1.06745234231254 2.93891122764907 0.654301901897971 2.40275905131978 0.554874927558593 0.671406517966396 0.875410817692793 0.873980330125277 0.681190036162572 4.22236484165125 4.77757735133414 4.30007776461534 0.789527541215174 0.925106104478774 0.688879264369203 1.25166398762041 2.37587126866179 0.714913600803787 1.32782494435457 1.25448362275782 2.29291959619943 1.792817394494 Pt15.baseline 3.26874248423954 1.36580930974817 0.977085906611747 2.64677498310874 0.637111547577296 2.12807749677546 0.569286436363017 0.756992079174756 0.881845240814033 0.670591671362158 0.672948338853483 3.85068558417918 4.4798460710427 3.96174551588059 0.901272039062649 0.974448947175485 0.606994989833774 1.22146290665565 2.23514556277652 0.726124738739789 1.12347125748889 1.20157664116323 2.12883907679371 1.71577441088351 Pt16.DP1 3.66273724929014 1.18597279448008 1.00889853709111 2.50757898538038 0.690106473157334 2.20243622146646 0.571981991005469 0.518579391825669 0.849942235654936 0.684944903473769 0.666634945930216 4.72876657645117 4.9250671976313 3.76307545751065 0.679674834912407 0.799495093324256 0.704472590220854 1.04739401458701 2.1656479954431 0.65711137547905 1.30694774444737 1.3731774705999 2.42806651134973 1.70802074520872 Pt16.baseline 4.13383987924013 1.12104006609458 1.02690170174354 2.62014034343511 0.684423504213153 2.46485783479918 0.608002902004162 0.745196152158281 0.848220289319081 0.658093921629698 0.663372959209166 4.88949598301518 4.77706756309095 3.71362334197653 0.721434018554012 0.857565334223203 0.725221575926362 1.2006756060119 2.30746883856456 0.674417618019037 1.31101988485048 1.38267507195361 2.50057623921561 1.76724771729288 Pt17.DP1 3.22429038287331 1.03309853530037 1.05411805554412 2.68587263750732 0.729686195263049 2.48665407822395 0.626447905037499 0.527028545940977 0.934989091033416 0.929043440343 0.69430673977013 4.84320256388129 4.68964308944841 3.77769195712885 1.03922763781273 0.923771173737675 0.792318888586606 1.14569486133333 2.45744186552559 0.87511780519978 1.3297098919609 1.52181517713311 2.30271830996403 1.9522683839152 Pt17.DP2 3.07760461913605 1.26110830472821 1.11886868155396 2.62257339158601 0.673487583530994 2.16299096776012 0.657921645002724 0.446693352077636 0.869262768547333 0.976337460322259 0.645153687538601 4.37129719769728 4.50088329059564 3.45857605179982 1.01633637779304 1.00390944728974 0.889757033384477 0.97315383671344 2.28299233031682 0.762413569289337 1.32407331725247 1.4587720500696 2.18202580276151 1.8128456253177 Pt17.baseline 3.20577977889408 1.24342596672796 1.13049971286823 2.84558608514125 0.823822706126231 2.62088576095098 0.693329107526488 0.541820506966611 0.945651391329522 0.936297572496973 0.716036462814273 4.91794891797834 4.42363947521344 4.09359187041873 1.01540998818371 1.11170390153251 0.688485131025048 0.987092236935054 2.64503081905911 0.905842333992966 1.58270135052459 1.47698812412947 2.47087853877618 2.03257898580298 Pt18.DD.DP1 3.69852204600307 1.10190589350571 0.964563529158326 2.4473716576496 0.417153761360978 2.40646087633784 0.709092663264595 0.803105345616847 0.820922194909332 0.92767813672705 0.641367910062381 4.83717509226477 4.85926684804087 3.52476495466684 0.684069838711545 1.01292698739471 0.798326820421479 1.29667223383063 2.24125857316893 0.661863144786005 1.29445337336341 1.3696714457693 2.67303953398058 1.59852871354428 Pt18.baseline 3.5881130209426 0.835807070700752 0.920129211332351 2.56956965836184 0.436631834397363 2.10922301082644 0.537735187839286 0.758478231266973 0.86872298435072 0.630556391415696 0.700435221075148 4.03686481761054 4.33198404353668 3.46489352517408 0.593819981482112 0.812622117466528 0.699658700715766 0.876646831924782 2.10261357335966 0.646672479546015 1.16612242913025 1.3864340136665 1.99357028152485 1.41395191257431 Pt19.DD.DP1 2.90628341750255 1.204531730021 0.947613682425239 1.9849952857156 0.601395252099504 2.11179496939742 0.441821871294769 0.60343102822632 0.736065144593592 0.651160209170397 0.652666291550247 3.99018956156543 4.51506532441669 3.02304644379191 0.74642291008196 1.0077704861923 0.554087132227888 1.12062021536492 2.22565251942919 0.581683932510191 0.830978632332038 1.29471304361604 2.23246637537876 1.66272855341901 Pt19.DD.DP2 3.81043478243332 1.04067242804712 1.18821737810376 2.42837636304627 0.665998040300362 2.21151109246256 0.726276829715252 0.822931488286853 0.804913926965236 0.770473519528775 0.67856335332509 4.42854074847277 4.27698643997408 3.20162122069918 0.87421956788053 1.00061368735762 0.95675937754355 1.33909522588494 2.2890718205613 0.783252561297206 1.20722362890707 1.57488126332508 2.5420004011041 1.92933943781685 Pt19.baseline 3.53719794776876 0.958478451126968 1.16803715290937 2.46270876129057 0.722443547438377 2.302364811526 0.652103964478705 0.668249493060951 0.856165343266317 0.886789833701296 0.680561832180039 4.55628123375396 4.67024663935883 3.50882575112862 0.877574781888288 1.08208908949762 0.774144250595942 1.32060281823016 2.3429467704965 0.797522840619669 1.0436818782305 1.50042258858722 2.56315375230781 1.78979512620532 Pt20.DD.DP1 3.93476920063398 1.09882405683352 1.08601094917341 2.68114121748392 0.51745326767465 2.70767513181449 0.618163264470632 0.486555049879733 0.827732460181674 0.997966135332566 0.571876419423732 4.69805241810197 5.44623356574622 3.60591243208275 0.776574246103653 0.903909473714438 1.00484771786156 0.991498008131167 2.25810648062173 0.740415341658153 1.73192538103865 1.49407536851619 2.94872987250023 1.51128572739839 Pt20.DP1 4.15733124049522 1.08154818570692 1.03640557105874 2.80307136503628 0.500576019987467 2.84316707711756 0.592645333289915 0.512166508573676 0.840695163216262 0.97280860538841 0.549581865986686 5.4070995914074 5.35592838971525 3.91573402974005 0.836147376952688 0.92674029637687 0.878584158790578 1.15843933287416 2.45693496085132 0.772187980806069 1.79131844266962 1.53521017821779 2.91937291549181 1.35491723013691 Pt20.baseline 3.73005921254357 1.15512745566009 1.03521787986939 2.8098761253717 0.499262310803323 2.86097685226196 0.609234318021404 0.523246329197975 0.767845557791498 0.912914955499754 0.586559846745607 4.76426595358486 5.30700019340407 3.93077051781368 0.868546752079646 0.980184493224782 0.817586876463011 1.21333761980093 2.33268763266406 0.75987397878969 1.6995593093557 1.43187993714902 2.81905143152262 1.37966408913305 Pt21.DD.DP1 3.96414967477315 1.08676231310452 0.879571741734051 2.65897113216933 0.708518270416787 2.40052738572751 0.597137607615559 0.573140044495729 0.769538008364926 0.915018863802352 0.655969078953257 5.23951554546345 4.64778771498438 3.8067127951758 0.721666422762091 0.871487981455437 0.458066969480161 1.20232538447155 2.15265559204478 0.696945549628636 1.07380243888497 1.55343822485404 2.808871760226 1.51491586597792 Pt21.DD.DP2 3.31342195095048 1.08452382910945 0.840174952836062 2.48394818681132 0.622912359003294 2.25885237544161 0.517149669162449 0.533176819738952 0.752757795590915 0.903948476782445 0.646955058691097 4.97241979092624 4.48978088569616 3.63148402726177 0.699160537448131 0.898439941051461 0.36202819588618 1.1129699452939 2.10084735669958 0.604783646882127 0.968789532529571 1.46115354196654 2.57647472774412 1.37546367063861 Pt21.DP2 4.02987483173921 1.11124583517126 0.910028818285132 2.66277815767409 0.680799410113433 2.27363288965169 0.554151117636634 0.716383830200561 0.721102889260452 0.840064480043604 0.661663552977521 4.80047407274671 4.47582714117293 3.96856121993355 0.817513111103168 0.847044385819122 0.497373869718787 1.4098355397709 2.07580995486078 0.613983052770939 1.37118164104103 1.43996248177486 2.46900185492995 1.46733002461322 Pt22.DD.DP1 2.54566767638179 1.00262705269586 0.860516352926722 2.46539200288906 0.744771760836372 2.12583989620376 0.301759472537963 0.55263508247669 0.822274724085749 0.71583281888747 0.495846319654055 3.61828658871394 4.39847004604089 4.11082123461888 0.395454764195269 0.655826746231576 0.313277412182096 1.30079572349282 2.06847059470311 0.558070015254368 0.827514403787408 0.902020177876702 1.86966651685667 1.28202794155898 Pt22.DD.DP2 2.55537094258123 0.973788190761404 0.891113027299906 2.51163694621735 0.698876784712137 2.23137767054839 0.295658435982307 0.501577252279323 0.805892585996479 0.784338268844495 0.489237139814238 3.87025740898572 4.73028466787092 4.16835818039721 0.441966998014056 0.624647118424517 0.329167030976921 1.31287695166317 2.09450362952212 0.563859485046389 0.839309941006519 0.940522661322997 1.99272329859307 1.21041078170723 Pt22.DD.DP3 2.46954568773409 0.946877553720544 0.883023251572445 2.57112843744257 0.630534179412066 2.27549453848745 0.31731266351957 0.483417861375435 0.816278958431659 0.835192087351302 0.485252176419937 3.84980918503163 4.50469626696564 4.24247759637671 0.481298339036697 0.614279953028407 0.327107935674872 1.39147430910069 2.15545174829426 0.560922805468597 0.830566680489899 0.926304293649058 1.96798122996599 1.15974892560466 Pt22.baseline1 2.74194032546697 0.962511475279853 0.956525256182537 2.58518949185693 0.580634389365105 2.13621509843105 0.299493476024099 0.613296043118324 0.801691364213013 0.70529259670235 0.596425325101514 4.20478733207641 4.56482513035656 4.29113014763637 0.580590052965156 0.669719595080821 0.320705274944235 1.65863389649831 2.37519387826543 0.697420891787717 1.03258626879835 1.04824949035053 2.1741881892522 1.21783925831252 Pt23.DD.DP1 3.8320949847499 1.14437068824789 1.10437086957699 2.68404352578707 0.941496635946398 2.06866033131782 0.821455099258302 0.645353792545548 0.919883210508313 1.06709690291555 0.736108767225753 4.99698405959199 4.55226926801925 3.74356980952451 1.09020201010869 1.03681109826414 1.03721290641458 1.31645021787877 2.54014499707372 1.06622924783891 1.35164102596859 1.66481178676889 2.63389093928103 2.15163988513621 Pt23.baseline 3.88061625372455 1.14617422351977 1.05531409641694 2.87417145854832 0.924721890794174 1.97437030147033 0.60693756292651 0.692076653793418 0.892678269245344 0.938213679525948 0.667348048020653 4.31735312210346 4.66692255512124 3.97547384445211 0.859402640654693 0.913166803376108 0.846413621417336 1.40024669970401 2.32426255283048 0.888062373170629 0.990832211045472 1.42311796181529 2.30075208255205 2.22394120746972 Pt24.DD.DP1 3.29677927162187 1.12894273000448 1.07697862218306 2.7381855880684 0.75964677371259 2.06709077101286 0.637506120108862 0.716174928545888 0.788106122859349 0.927825766219445 0.53019528758018 4.7533989377216 4.39426147797383 3.65873104787652 0.816236536431094 0.969255115965783 0.681655122717045 1.20220531341874 2.23220204211737 0.692883290975485 1.0550668572431 1.31742259407444 2.55002047293064 1.72851201049369 Pt24.baseline 3.5590792360603 1.19067864782356 0.953428476537383 2.34994342970792 0.656221688811981 2.42169148880083 0.603280251990844 0.704382445550397 0.727097329426341 0.936624007207934 0.62915297727511 5.2571907466356 4.74053696625859 3.18140146094423 0.803022294594958 0.789939787457966 0.65270393385661 1.22960851178512 2.19948544180334 0.777674836172755 1.27427582140064 1.53174456123482 2.76677727607393 1.66567142942022 M229.DMSO2D 4.12798186809631 1.10765239744392 0.986419523211405 2.77109818470513 0.499649337752155 2.32858369030117 0.073114608768304 0.389309142112688 0.650683656952563 0.460720277981127 0.42720793353309 6.21014722153271 4.66182103502203 4.04156864188819 0.518116957183319 0.725666671684301 0.483893256718145 1.70976194464134 1.8937387779192 0.372385090796058 1.37940339160944 0.767320010213234 2.01248588748249 1.10475532952066 M229R5.PLX 3.00454619583462 1.03547545731382 1.14289386124519 0.931367003346302 0.47949368631084 2.25614280222725 0.0763455406193569 0.291060461659012 0.602669866385069 0.376969099089391 0.382641705747654 6.3309657295597 4.4913688028883 1.49229866602005 0.435438365044905 0.650166729509234 0.296339618826441 0.805028210857364 1.5535860684 0.249213859012721 1.36961416821962 0.777834760968814 2.12292581835376 1.18660331044186 M229DDRpoly.PLXAZD 2.80863118404273 0.765841203548534 1.11435947577592 1.08650493211478 0.515437145490314 1.94751364689013 0.223469867609409 0.123652464526584 0.596224484479571 0.320515055873807 0.3815301716649 4.9184611581082 4.25254886008714 1.7257340267363 0.382606396114129 0.701436364597799 0.422484570675426 0.841761886317665 1.8042545200947 0.346691901694705 1.17336108309694 1.04586895135215 1.64134247287729 1.124504875027 M238.DMSO2D 3.83258047000331 1.21619313937305 0.978647206317152 2.53598482939146 0.481016917226472 3.42677360983134 0.120524671423913 0.370632769331291 0.646734997028215 0.318663186794377 0.53537980527913 5.42597895615288 4.35822916380808 3.48989834859366 0.599573437151501 0.602996019242352 0.400667690874966 1.63989995406077 1.85984639206809 0.419100352341022 1.48421799606612 0.921573115730528 3.0372035459703 0.996330354963061 M238R1.PLX 3.2823247703182 0.96924856061568 1.10452161114302 0.915497333122848 0.520574485264617 2.67232957880311 -0.023242363649131 0.313088613194047 0.643180164679721 0.276503124350523 0.509920851615023 5.11291480661718 4.199575177098 1.30153400706374 0.455977906219459 0.496542621416117 0.351163457150601 0.618588500311225 1.73345059626468 0.286777711063129 1.27748842473183 1.00389495185334 2.61673436684482 1.20918989376881 SKMel28.DMSO 2.67263310697436 0.943076119736207 0.857243577455274 2.46583519971075 0.600378199870513 2.38120700462979 0.0784110973865125 0.360946970710206 0.798513616626038 0.609588374177743 0.50244948310808 4.56521428325692 4.34153705963826 4.15636990157061 0.606193303929817 0.684407829432243 0.258105202072201 1.55205651386404 2.10252749926649 0.511321496905782 1.11081386947557 1.04412877687647 2.21680318417481 1.30089845103747 SKMel28R1.PLX 2.91032105314693 0.94919418929509 1.07625845152148 0.801170469099234 0.675783187085388 1.94376246382735 0.0873155575607455 0.43148932939257 0.753756540958785 0.363878658772546 0.499950467227083 4.81027115801279 4.29221253002365 1.53246649547753 0.507736837538883 0.781959352556063 0.446334309478294 0.647403300156891 1.83549712913851 0.36280749668947 1.2756678596779 1.15289658684681 2.0361259012101 1.30010898956022 SKMel28DDR1.PLXAZD 2.71895640473873 0.89710323837648 1.08500576638831 1.03035853501371 0.588671420791658 1.84052974015715 0.00472280839993803 0.619331764821841 0.748968759536831 0.413719697819248 0.499288667931663 4.75072935960816 3.96449103813435 1.76625900816588 0.570493271690604 0.69417824864954 0.372066392601102 0.707655680538763 1.78804036691588 0.308887248303365 1.30228280280115 1.15077207894421 1.89353743771655 1.40131617094272