| Basic Information ▶ | |
| VISDB ID | TVIS10016534 |
|---|---|
| Fusion Name | HBV-FGF13 integration |
| Validated | No |
| Curated Way | VISDB1.0 |
| Method | Whole-genome sequencing |
| Wet Assay | No |
| Sample ID | 31656 |
| Sample Name | 31656T |
| Sample Type | Tumor |
| Age | 45 |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Hepatocellular carcinoma |
| Disease Abbreviation | HCC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 22267523 |
| Journal | Genome Research |
| Published Year | 2012 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chrX |
| Cytogenetic Band | q26.3 |
| Human Strand | - |
| Human Integration Location Type | Intronic |
| Hg19 Start | 137807487 |
| Hg19 End | 137807522 |
| Hg38 Start | 138725325 |
| Hg38 End | 138725360 |
| Junction Sequence | TACACGAATAATACTGCACCAACAGGTCTGTAGGA |
| Target Gene ▶ | |
| Target Gene | FGF13 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | - |
| Virus Genome Accession | NC_003977 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus (strain ayw) genome |
| Virus Genome Length | 3182 |
| Virus Breakpoint1 | 3051 |
| Virus Breakpoint2 | 3086 |
| Virus Gene Name | - |
| Virus Region Type | - |
| Integrated Virus Sequence | CTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAA |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000129682.17 |
| Gene Name | FGF13 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000305414.9, Transcript 2: ENST00000436198.6, Transcript 3: ENST00000441825.8, Transcript 4: ENST00000626909.2, Transcript 5: ENST00000455663.5, Transcript 6: ENST00000448673.1 |
| AlphaGenome Analysis | |
| Window | chrX:138659789-138790861 |
| RNA-seq Change (±2kb) | Mean: -8.085829904302955e-05 | Peak: 0.0228271484375 |
| ATAC Change (±2kb) | Mean: -0.0001343539624940604 | Peak: 1.4884796142578125 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -0.7% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D