| Basic Information ▶ | |
| VISDB ID | TVIS10016984 |
|---|---|
| Fusion Name | HBV-LINC02319 integration |
| Validated | No |
| Curated Way | VISDB1.0 |
| Method | Capture based next-generation sequencing |
| Wet Assay | No |
| Sample ID | M14 |
| Sample Name | M14 |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Hepatocellular carcinoma |
| Disease Abbreviation | HCC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 30070724 |
| Journal | Hepatology |
| Published Year | 2019 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr14 |
| Cytogenetic Band | q22.1 |
| Human Strand | |
| Human Integration Location Type | Intronic |
| Hg19 Start | 52591733 |
| Hg19 End | 52591786 |
| Hg38 Start | 52125015 |
| Hg38 End | 52125068 |
| Junction Sequence | TCCCTAAGGGACACTACAGGAAACCAGCCCCGAAGTGATTTCTTTTGAAATTC |
| Target Gene ▶ | |
| Target Gene | LINC02319 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | B |
| Virus Genome Accession | NC_003977 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus (strain ayw) genome |
| Virus Genome Length | 3182 |
| Virus Breakpoint1 | 2888 |
| Virus Breakpoint2 | 2970 |
| Virus Gene Name | - |
| Virus Region Type | - |
| Integrated Virus Sequence | TTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTG |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000258694.2 |
| Gene Name | LINC02319 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000726397.1, Transcript 2: ENST00000726401.1, Transcript 3: ENST00000726400.1, Transcript 4: ENST00000726398.1, Transcript 5: ENST00000555852.1, Transcript 6: ENST00000726399.1 |
| AlphaGenome Analysis | |
| Window | chr14:52059479-52190551 |
| RNA-seq Change (±2kb) | Mean: 4.9555132136447355e-05 | Peak: 0.018310546875 |
| ATAC Change (±2kb) | Mean: -0.001545346574857831 | Peak: 6.2162322998046875 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -3.9% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D