| Basic Information ▶ | |
| VISDB ID | TVIS10017195 |
|---|---|
| Fusion Name | HBV-chr8 integration |
| Validated | No |
| Curated Way | VISDB1.0 |
| Method | Capture based next-generation sequencing |
| Wet Assay | No |
| Sample ID | M49 |
| Sample Name | M49 |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Hepatocellular carcinoma |
| Disease Abbreviation | HCC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 30070724 |
| Journal | Hepatology |
| Published Year | 2019 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr8 |
| Cytogenetic Band | q23.2 |
| Human Strand | |
| Human Integration Location Type | Intergenic |
| Hg19 Start | 111700385 |
| Hg19 End | 111700499 |
| Hg38 Start | 110688156 |
| Hg38 End | 110688270 |
| Junction Sequence | attccagaaagcaagagaaataaattccaagagagtataacaaaagggctgctgtaaatatatttgaagaagaaaatcaacccatcttagctttcaaggaagcactcaatttta |
| Target Gene ▶ | |
| Target Gene | - |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | B |
| Virus Genome Accession | NC_003977 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus (strain ayw) genome |
| Virus Genome Length | 3182 |
| Virus Breakpoint1 | 2554 |
| Virus Breakpoint2 | 2639 |
| Virus Gene Name | - |
| Virus Region Type | - |
| Integrated Virus Sequence | CATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTAT |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Region | intergenic |
| Impact | NA |
| AlphaGenome Analysis | |
| Window | chr8:110622620-110753692 |
| RNA-seq Change (±2kb) | Mean: -3.5633504467114108e-06 | Peak: 0.00795745849609375 |
| ATAC Change (±2kb) | Mean: -0.0004616023215930909 | Peak: 1.515612006187439 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -1.9% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D