| Basic Information ▶ | |
| VISDB ID | TVIS10047094 |
|---|---|
| Fusion Name | HBV-ENSG00000250658 integration |
| Validated | No |
| Curated Way | Curated |
| Method | HBV capture sequencing |
| Wet Assay | Yes |
| Sample ID | 2688 |
| Sample Name | #2688N |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | - |
| Disease Abbreviation | - |
| Cancer | - |
| Literature ▶ | |
| PubMed ID | 33563643 |
| Journal | Gut |
| Published Year | 2021 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr4 |
| Cytogenetic Band | q35.2 |
| Human Strand | |
| Human Integration Location Type | intronic |
| Hg19 Start | 188343823 |
| Hg19 End | 188343823 |
| Hg38 Start | 187422669 |
| Hg38 End | 187422669 |
| Junction Sequence | CCTCACGGACCATTTACCCT |
| Target Gene ▶ | |
| Target Gene | ENSG00000250658 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | HBV_C |
| Virus Genome Accession | AB014381 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus 22Y04HCC genomic DNA, complete sequence |
| Virus Genome Length | 3215 bp |
| Virus Breakpoint1 | 1922 |
| Virus Breakpoint2 | - |
| Virus Gene Name | - |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000250658.2 |
| Gene Name | ENSG00000250658 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000795561.1, Transcript 2: ENST00000795547.1, Transcript 3: ENST00000795549.1, Transcript 4: ENST00000795551.1, Transcript 5: ENST00000795550.1, Transcript 6: ENST00000795548.1, Transcript 7: ENST00000795552.1, Transcript 8: ENST00000795553.1, Transcript 9: ENST00000795554.1, Transcript 10: ENST00000795555.1 |
| AlphaGenome Analysis | |
| Window | chr4:187357133-187488205 |
| RNA-seq Change (±2kb) | Mean: -6.13869124208577e-05 | Peak: 0.0350341796875 |
| ATAC Change (±2kb) | Mean: -7.859634206397459e-05 | Peak: 4.468733787536621 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -0.4% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D