| Basic Information ▶ | |
| VISDB ID | TVIS10048116 |
|---|---|
| Fusion Name | HBV-BEGAIN integration |
| Validated | No |
| Curated Way | Curated |
| Method | HBV capture sequencing |
| Wet Assay | Yes |
| Sample ID | 3798 |
| Sample Name | #3798N |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | - |
| Disease Abbreviation | - |
| Cancer | - |
| Literature ▶ | |
| PubMed ID | 33563643 |
| Journal | Gut |
| Published Year | 2021 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr14 |
| Cytogenetic Band | q32.2 |
| Human Strand | |
| Human Integration Location Type | intronic |
| Hg19 Start | 101017936 |
| Hg19 End | 101017936 |
| Hg38 Start | 100551599 |
| Hg38 End | 100551599 |
| Junction Sequence | TGGATAATTTAACATTTTTC |
| Target Gene ▶ | |
| Target Gene | BEGAIN |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | HBV_C |
| Virus Genome Accession | AB014381 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus 22Y04HCC genomic DNA, complete sequence |
| Virus Genome Length | 3215 bp |
| Virus Breakpoint1 | 1818 |
| Virus Breakpoint2 | - |
| Virus Gene Name | - |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000183092.19 |
| Gene Name | BEGAIN |
| Transcript | Transcript 1: ENST00000557378.6, Transcript 2: ENST00000637646.1, Transcript 3: ENST00000553553.6, Transcript 4: ENST00000556188.6, Transcript 5: ENST00000355173.7, Transcript 6: ENST00000637716.2, Transcript 7: ENST00000554140.3, Transcript 8: ENST00000965912.1, Transcript 9: ENST00000556751.5, Transcript 10: ENST00000554747.1 |
| Transcript 1 Region | intron |
| Transcript 1 Impact | intronic_insertion |
| Transcript 2 Region | intron |
| Transcript 2 Impact | intronic_insertion |
| Transcript 3 Region | intron |
| Transcript 3 Impact | intronic_insertion |
| Transcript 4 Region | intron |
| Transcript 4 Impact | intronic_insertion |
| Transcript 5 Region | intron |
| Transcript 5 Impact | intronic_insertion |
| Transcript 6 Region | intron |
| Transcript 6 Impact | intronic_insertion |
| Transcript 7 Region | intron |
| Transcript 7 Impact | intronic_insertion |
| Transcript 8 Region | intron |
| Transcript 8 Impact | intronic_insertion |
| Transcript 9 Region | promoter |
| Transcript 9 Impact | promoter_insertion |
| Transcript 10 Region | intron |
| Transcript 10 Impact | intronic_insertion |
| SpliceAI Score | |
| Delta Scores | Acceptor Gain: 0.040 | Acceptor Loss: 0.040 | Donor Gain: 0.040 | Donor Loss: 0.010 |
| Delta Score Max | 0.040 |
| Delta Position at Max | 363 |
| Delta Score Flag | LOW |
| Gene | BEGAIN |
| AlphaGenome Analysis | |
| Window | chr14:100486063-100617135 |
| RNA-seq Change (±2kb) | Mean: -0.0008543496369384229 | Peak: 0.07275390625 |
| ATAC Change (±2kb) | Mean: -0.0007262635626830161 | Peak: 2.0390625 |
| Interpretation | RNA-seq: minimal change -6.9% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -1.3% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D