| Basic Information ▶ | |
| VISDB ID | TVIS10051437 |
|---|---|
| Fusion Name | HBV-SET integration |
| Validated | No |
| Curated Way | Curated |
| Method | EBV capture sequencing, followed by Viral Integration Pathway Analysis (VIPA) pipeline |
| Wet Assay | No |
| Sample ID | SRR3104939.3 |
| Sample Name | SRA335342 |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Hepatocellular carcinoma |
| Disease Abbreviation | HCC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 35968887 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2022 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | chr9 |
| Cytogenetic Band | q34.11 |
| Human Strand | + |
| Human Integration Location Type | intronic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 128688417 |
| Hg38 End | 128688417 |
| Junction Sequence | TAGTGGTTCAGAACTTTGCCTCTCAAGTAGAACTTGTTGGCCCCTTTCATCTCTATGAACAGAACACCTCCTTTCCATGGCTGCTAGGGTGtGCTGCCAA |
| Target Gene ▶ | |
| Target Gene | SET |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | - |
| Virus Genome Accession | AB014381 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus 22Y04HCC genomic DNA, complete sequence |
| Virus Genome Length | 3215 bp |
| Virus Breakpoint1 | 1361 |
| Virus Breakpoint2 | - |
| Virus Gene Name | X,P |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000119335.19 |
| Gene Name | SET |
| Transcript | Transcript 1: ENST00000686840.1, Transcript 2: ENST00000372692.8, Transcript 3: ENST00000921998.1, Transcript 4: ENST00000691158.1, Transcript 5: ENST00000686568.1, Transcript 6: ENST00000409104.7, Transcript 7: ENST00000322030.13, Transcript 8: ENST00000878517.1, Transcript 9: ENST00000878518.1, Transcript 10: ENST00000921999.1, Transcript 11: ENST00000372688.9, Transcript 12: ENST00000968516.1, Transcript 13: ENST00000372686.6, Transcript 14: ENST00000466009.5, Transcript 15: ENST00000477806.5, Transcript 16: ENST00000480217.5, Transcript 17: ENST00000480536.2 |
| Transcript 1 Region | intron |
| Transcript 1 Impact | intronic_insertion |
| Transcript 2 Region | intron |
| Transcript 2 Impact | intronic_insertion |
| Transcript 3 Region | intron |
| Transcript 3 Impact | intronic_insertion |
| Transcript 4 Region | intron |
| Transcript 4 Impact | intronic_insertion |
| Transcript 5 Region | intron |
| Transcript 5 Impact | intronic_insertion |
| Transcript 6 Region | intron |
| Transcript 6 Impact | intronic_insertion |
| Transcript 7 Region | promoter |
| Transcript 7 Impact | promoter_insertion |
| Transcript 8 Region | promoter |
| Transcript 8 Impact | promoter_insertion |
| Transcript 9 Region | promoter |
| Transcript 9 Impact | promoter_insertion |
| Transcript 10 Region | promoter |
| Transcript 10 Impact | promoter_insertion |
| Transcript 11 Region | promoter |
| Transcript 11 Impact | promoter_insertion |
| Transcript 12 Region | promoter |
| Transcript 12 Impact | promoter_insertion |
| Transcript 13 Region | promoter |
| Transcript 13 Impact | promoter_insertion |
| Transcript 14 Region | promoter |
| Transcript 14 Impact | promoter_insertion |
| Transcript 15 Region | promoter |
| Transcript 15 Impact | promoter_insertion |
| Transcript 16 Region | promoter |
| Transcript 16 Impact | promoter_insertion |
| Transcript 17 Region | promoter |
| Transcript 17 Impact | promoter_insertion |
| AlphaGenome Analysis | |
| Window | chr9:128622881-128753953 |
| RNA-seq Change (±2kb) | Mean: -0.006576988846063614 | Peak: 37.7291259765625 |
| ATAC Change (±2kb) | Mean: 0.004629346542060375 | Peak: 160.4765625 |
| Interpretation | RNA-seq: minimal change -2.2% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change 0.9% |
| Visualization | |