| Basic Information ▶ | |
| VISDB ID | TVIS10051876 |
|---|---|
| Fusion Name | HBV-ENSG00000300381 integration |
| Validated | No |
| Curated Way | Curated |
| Method | EBV capture sequencing, followed by Viral Integration Pathway Analysis (VIPA) pipeline |
| Wet Assay | No |
| Sample ID | SRR3105051.6 |
| Sample Name | SRA335342 |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Hepatocellular carcinoma |
| Disease Abbreviation | HCC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 35968887 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2022 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | chr5 |
| Cytogenetic Band | p15.33 |
| Human Strand | + |
| Human Integration Location Type | intronic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 1295276 |
| Hg38 End | 1295276 |
| Junction Sequence | nngnCCCCAGTCCCTCCGaCCACGTGGGAAGCcccgacagcgcagctgctccggGCGGTCCTGGGCGTCTGTGCCCGCGAATCCACTGGGAGCGTTGCATGGTGCTGGTGAACAGACCAATTTATGCCTACAGCCTCCTAGTACAAAGAGATGatt |
| Target Gene ▶ | |
| Target Gene | ENSG00000300381 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | - |
| Virus Genome Accession | AB014381 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus 22Y04HCC genomic DNA, complete sequence |
| Virus Genome Length | 3215 bp |
| Virus Breakpoint1 | 1820 |
| Virus Breakpoint2 | - |
| Virus Gene Name | X,C |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Transcript | Transcript 1: ENST00000656021.1, Transcript 2: ENST00000310581.10, Transcript 3: ENST00000922986.1, Transcript 4: ENST00000922985.1, Transcript 5: ENST00000334602.10, Transcript 6: ENST00000460137.6, Transcript 7: ENST00000771252.1 |
| Transcript 1 Gene Id | ENSG00000164362.22 |
| Transcript 1 Gene Name | TERT |
| Transcript 1 Region | promoter |
| Transcript 1 Impact | promoter_insertion |
| Transcript 2 Gene Id | ENSG00000164362.22 |
| Transcript 2 Gene Name | TERT |
| Transcript 2 Region | promoter |
| Transcript 2 Impact | promoter_insertion |
| Transcript 3 Gene Id | ENSG00000164362.22 |
| Transcript 3 Gene Name | TERT |
| Transcript 3 Region | promoter |
| Transcript 3 Impact | promoter_insertion |
| Transcript 4 Gene Id | ENSG00000164362.22 |
| Transcript 4 Gene Name | TERT |
| Transcript 4 Region | promoter |
| Transcript 4 Impact | promoter_insertion |
| Transcript 5 Gene Id | ENSG00000164362.22 |
| Transcript 5 Gene Name | TERT |
| Transcript 5 Region | promoter |
| Transcript 5 Impact | promoter_insertion |
| Transcript 6 Gene Id | ENSG00000164362.22 |
| Transcript 6 Gene Name | TERT |
| Transcript 6 Region | promoter |
| Transcript 6 Impact | promoter_insertion |
| Transcript 7 Gene Id | ENSG00000300381.1 |
| Transcript 7 Gene Name | ENSG00000300381 |
| Transcript 7 Region | intron |
| Transcript 7 Impact | intronic_insertion |
| AlphaGenome Analysis | |
| Chromosome | chr5 |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D