| Basic Information ▶ | |
| VISDB ID | TVIS10053956 |
|---|---|
| Fusion Name | HBV-NC_000022.11:11817798 integration |
| Validated | No |
| Curated Way | Curated |
| Method | High-throughput HBV integration sequencing method |
| Wet Assay | Yes |
| Sample ID | - |
| Sample Name | Pt_0501_NT |
| Sample Type | Tumor |
| Age | 58 |
| Gender | Male |
| Disease Information ▶ | |
| Disease Name | - |
| Disease Abbreviation | - |
| Cancer | - |
| Literature ▶ | |
| PubMed ID | 37400627 |
| Journal | Communications Biology |
| Published Year | 2023 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | NC_000022.11 |
| Cytogenetic Band | |
| Human Strand | - |
| Human Integration Location Type | |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 11817798 |
| Hg38 End | 11817639 |
| Junction Sequence | AAGGTGGAGATATGCGCTGTATAAACATTCTTTTGCTCTGGAACCCCGTAGAGACTTGGGAGCCAGTTGGGTGGAGCATTCGTTGGATGAGGGTGCTCGGGTTAGGAATATCAAGGTGTGGCTCCAGATAATCCAATCATCTAATTAAGATTCCAGTTAT |
| Target Gene ▶ | |
| Target Gene | - |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | HBV genotype D |
| Virus Genome Accession | NC_003977.2 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus (strain ayw) genome |
| Virus Genome Length | 3182 bp |
| Virus Breakpoint1 | 1772 |
| Virus Breakpoint2 | 1849 |
| Virus Gene Name | X/ENH2/BCP |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000290397.2 |
| Gene Name | ENSG00000290397 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000849412.1, Transcript 2: ENST00000849405.1, Transcript 3: ENST00000849409.1, Transcript 4: ENST00000849411.1, Transcript 5: ENST00000849403.1, Transcript 6: ENST00000849408.1, Transcript 7: ENST00000849404.1, Transcript 8: ENST00000849402.1, Transcript 9: ENST00000849410.1, Transcript 10: ENST00000849406.1, Transcript 11: ENST00000849407.1 |
| AlphaGenome Analysis | |
| Window | chr22:11752262-11883334 |
| RNA-seq Change (±2kb) | Mean: 3.182376531185582e-05 | Peak: 0.061767578125 |
| ATAC Change (±2kb) | Mean: 0.00027781040989793837 | Peak: 0.9055061340332031 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change 1.5% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D