| Basic Information ▶ | |
| VISDB ID | TVIS10054467 |
|---|---|
| Fusion Name | HBV-NC_000013.11:29059830 integration |
| Validated | No |
| Curated Way | Curated |
| Method | High-throughput HBV integration sequencing method |
| Wet Assay | Yes |
| Sample ID | - |
| Sample Name | Pt_0501_T |
| Sample Type | Tumor |
| Age | 58 |
| Gender | Male |
| Disease Information ▶ | |
| Disease Name | Hepatocellular Carcinoma |
| Disease Abbreviation | HCC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 37400627 |
| Journal | Communications Biology |
| Published Year | 2023 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | NC_000013.11 |
| Cytogenetic Band | NA |
| Human Strand | + |
| Human Integration Location Type | intergenic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 29059830 |
| Hg38 End | 29059891 |
| Junction Sequence | TATGTTGCCCATCTAGCTACCACTGGCAAGGGTGGGGTTGTTTACTTTGCCATCTGGTGGCT |
| Target Gene ▶ | |
| Target Gene | - |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | HBV genotype D |
| Virus Genome Accession | NC_003977.2 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus (strain ayw) genome |
| Virus Genome Length | 3182 bp |
| Virus Breakpoint1 | 54 |
| Virus Breakpoint2 | 222 |
| Virus Gene Name | preS1/preS2/S |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000132938.23 |
| Gene Name | MTUS2 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000948542.1, Transcript 2: ENST00000612955.6 |
| AlphaGenome Analysis | |
| Window | chr13:28994294-29125366 |
| RNA-seq Change (±2kb) | Mean: 7.641325646545738e-05 | Peak: 0.1044921875 |
| ATAC Change (±2kb) | Mean: 0.003939593676477671 | Peak: 13.45703125 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: INCREASED 16.8% (REF=0.02, ALT=0.03) |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D