| Basic Information ▶ | |
| VISDB ID | TVIS10054799 |
|---|---|
| Fusion Name | HBV-NC_000021.9:44321593 integration |
| Validated | No |
| Curated Way | Curated |
| Method | High-throughput HBV integration sequencing method |
| Wet Assay | Yes |
| Sample ID | - |
| Sample Name | Pt_0502_NT |
| Sample Type | Tumor |
| Age | 72 |
| Gender | Male |
| Disease Information ▶ | |
| Disease Name | - |
| Disease Abbreviation | - |
| Cancer | - |
| Literature ▶ | |
| PubMed ID | 37400627 |
| Journal | Communications Biology |
| Published Year | 2023 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | NC_000021.9 |
| Cytogenetic Band | NA |
| Human Strand | + |
| Human Integration Location Type | intergenic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 44321593 |
| Hg38 End | 44321696 |
| Junction Sequence | GTGTGCTGGGCAGCGTCCAGGCTGCTGGCAGGGCCTGGCCCCTTTTTCCAGAACCTGCCGGCCTGCTGACCTCCTGTGCAGGTTGGGGGTCCCCTCCCCGTCTG |
| Target Gene ▶ | |
| Target Gene | - |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | HBV genotype D |
| Virus Genome Accession | NC_003977.2 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus (strain ayw) genome |
| Virus Genome Length | 3182 bp |
| Virus Breakpoint1 | 1489 |
| Virus Breakpoint2 | 1542 |
| Virus Gene Name | X |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000141959.18 |
| Gene Name | PFKL |
| Transcript | Transcript 1: ENST00000885166.1, Transcript 2: ENST00000916368.1, Transcript 3: ENST00000885165.1, Transcript 4: ENST00000885167.1, Transcript 5: ENST00000885169.1, Transcript 6: ENST00000885168.1, Transcript 7: ENST00000946328.1, Transcript 8: ENST00000885170.1, Transcript 9: ENST00000885174.1, Transcript 10: ENST00000885173.1, Transcript 11: ENST00000916369.1, Transcript 12: ENST00000885172.1, Transcript 13: ENST00000885171.1, Transcript 14: ENST00000946329.1, Transcript 15: ENST00000946330.1, Transcript 16: ENST00000397961.6, Transcript 17: ENST00000885176.1, Transcript 18: ENST00000349048.9, Transcript 19: ENST00000885175.1, Transcript 20: ENST00000885177.1, Transcript 21: ENST00000946331.1, Transcript 22: ENST00000946337.1, Transcript 23: ENST00000946332.1, Transcript 24: ENST00000885178.1, Transcript 25: ENST00000885179.1, Transcript 26: ENST00000946333.1, Transcript 27: ENST00000946335.1, Transcript 28: ENST00000946334.1, Transcript 29: ENST00000946336.1, Transcript 30: ENST00000885182.1, Transcript 31: ENST00000885185.1, Transcript 32: ENST00000946338.1, Transcript 33: ENST00000885183.1, Transcript 34: ENST00000885181.1, Transcript 35: ENST00000885180.1, Transcript 36: ENST00000946339.1, Transcript 37: ENST00000885184.1, Transcript 38: ENST00000466134.5, Transcript 39: ENST00000474114.5, Transcript 40: ENST00000498841.5, Transcript 41: ENST00000460020.5, Transcript 42: ENST00000467315.5, Transcript 43: ENST00000460521.5, Transcript 44: ENST00000495274.1 |
| Transcript 1 Region | intron |
| Transcript 1 Impact | intronic_insertion |
| Transcript 2 Region | intron |
| Transcript 2 Impact | intronic_insertion |
| Transcript 3 Region | intron |
| Transcript 3 Impact | intronic_insertion |
| Transcript 4 Region | intron |
| Transcript 4 Impact | intronic_insertion |
| Transcript 5 Region | intron |
| Transcript 5 Impact | intronic_insertion |
| Transcript 6 Region | intron |
| Transcript 6 Impact | intronic_insertion |
| Transcript 7 Region | intron |
| Transcript 7 Impact | intronic_insertion |
| Transcript 8 Region | intron |
| Transcript 8 Impact | intronic_insertion |
| Transcript 9 Region | intron |
| Transcript 9 Impact | intronic_insertion |
| Transcript 10 Region | intron |
| Transcript 10 Impact | intronic_insertion |
| Transcript 11 Region | intron |
| Transcript 11 Impact | intronic_insertion |
| Transcript 12 Region | intron |
| Transcript 12 Impact | intronic_insertion |
| Transcript 13 Region | intron |
| Transcript 13 Impact | intronic_insertion |
| Transcript 14 Region | intron |
| Transcript 14 Impact | intronic_insertion |
| Transcript 15 Region | intron |
| Transcript 15 Impact | intronic_insertion |
| Transcript 16 Region | intron |
| Transcript 16 Impact | intronic_insertion |
| Transcript 17 Region | intron |
| Transcript 17 Impact | intronic_insertion |
| Transcript 18 Region | intron |
| Transcript 18 Impact | intronic_insertion |
| Transcript 19 Region | intron |
| Transcript 19 Impact | intronic_insertion |
| Transcript 20 Region | intron |
| Transcript 20 Impact | intronic_insertion |
| Transcript 21 Region | intron |
| Transcript 21 Impact | intronic_insertion |
| Transcript 22 Region | intron |
| Transcript 22 Impact | intronic_insertion |
| Transcript 23 Region | intron |
| Transcript 23 Impact | intronic_insertion |
| Transcript 24 Region | intron |
| Transcript 24 Impact | intronic_insertion |
| Transcript 25 Region | intron |
| Transcript 25 Impact | intronic_insertion |
| Transcript 26 Region | intron |
| Transcript 26 Impact | intronic_insertion |
| Transcript 27 Region | intron |
| Transcript 27 Impact | intronic_insertion |
| Transcript 28 Region | intron |
| Transcript 28 Impact | intronic_insertion |
| Transcript 29 Region | intron |
| Transcript 29 Impact | intronic_insertion |
| Transcript 30 Region | intron |
| Transcript 30 Impact | intronic_insertion |
| Transcript 31 Region | intron |
| Transcript 31 Impact | intronic_insertion |
| Transcript 32 Region | intron |
| Transcript 32 Impact | intronic_insertion |
| Transcript 33 Region | intron |
| Transcript 33 Impact | intronic_insertion |
| Transcript 34 Region | intron |
| Transcript 34 Impact | intronic_insertion |
| Transcript 35 Region | intron |
| Transcript 35 Impact | intronic_insertion |
| Transcript 36 Region | intron |
| Transcript 36 Impact | intronic_insertion |
| Transcript 37 Region | intron |
| Transcript 37 Impact | intronic_insertion |
| Transcript 38 Region | intron |
| Transcript 38 Impact | intronic_insertion |
| Transcript 39 Region | exon_non_coding |
| Transcript 39 Impact | noncoding_exon_insertion |
| Transcript 40 Region | intron |
| Transcript 40 Impact | intronic_insertion |
| Transcript 41 Region | intron |
| Transcript 41 Impact | intronic_insertion |
| Transcript 42 Region | intron |
| Transcript 42 Impact | intronic_insertion |
| Transcript 43 Region | exon_non_coding |
| Transcript 43 Impact | noncoding_exon_insertion |
| Transcript 44 Region | promoter |
| Transcript 44 Impact | promoter_insertion |
| AlphaGenome Analysis | |
| Window | chr21:44256057-44387129 |
| RNA-seq Change (±2kb) | Mean: 0.006921642925590277 | Peak: 15.6788330078125 |
| ATAC Change (±2kb) | Mean: -1.4980190826463513e-05 | Peak: 4.374698638916016 |
| Interpretation | RNA-seq: minimal change 2.6% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -0.0% |
| Visualization | |