| Basic Information ▶ | |
| VISDB ID | TVIS10056536 |
|---|---|
| Fusion Name | HBV-NC_000005.10:768526 integration |
| Validated | No |
| Curated Way | Curated |
| Method | High-throughput HBV integration sequencing method |
| Wet Assay | Yes |
| Sample ID | - |
| Sample Name | Pt_0506_T |
| Sample Type | Tumor |
| Age | 54 |
| Gender | Male |
| Disease Information ▶ | |
| Disease Name | Hepatocellular Carcinoma |
| Disease Abbreviation | HCC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 37400627 |
| Journal | Communications Biology |
| Published Year | 2023 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | NC_000005.10 |
| Cytogenetic Band | |
| Human Strand | - |
| Human Integration Location Type | |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 768526 |
| Hg38 End | 768417 |
| Junction Sequence | CTGTGCCTTGGGTCTGGCCTGTGTGTTCTCTCCATCTGCACTGCTGCCTCCTGGCTGCGCTGCTGCTGGGACCTCCTGCATGGCCCCACCCTCCACTTCTCCACCTCTGC |
| Target Gene ▶ | |
| Target Gene | - |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Hepatitis B virus |
| Virus Subtype Name | HBV genotype D |
| Virus Genome Accession | NC_003977.2 |
| TaxonomyID | 10407 |
| Virus Abbreviation | HBV |
| Virus Genome | Hepatitis B virus (strain ayw) genome |
| Virus Genome Length | 3182 bp |
| Virus Breakpoint1 | 1772 |
| Virus Breakpoint2 | 1891 |
| Virus Gene Name | PreCore/Core,X/ENH2/BCP |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Transcript | Transcript 1: ENST00000522356.3, Transcript 2: ENST00000508859.8, Transcript 3: ENST00000962634.1, Transcript 4: ENST00000651714.1, Transcript 5: ENST00000651221.1, Transcript 6: ENST00000652055.1, Transcript 7: ENST00000651083.1, Transcript 8: ENST00000506203.2 |
| Transcript 1 Gene Id | ENSG00000206077.15 |
| Transcript 1 Gene Name | ZDHHC11B |
| Transcript 1 Region | intron |
| Transcript 1 Impact | intronic_insertion |
| Transcript 2 Gene Id | ENSG00000206077.15 |
| Transcript 2 Gene Name | ZDHHC11B |
| Transcript 2 Region | intron |
| Transcript 2 Impact | intronic_insertion |
| Transcript 3 Gene Id | ENSG00000206077.15 |
| Transcript 3 Gene Name | ZDHHC11B |
| Transcript 3 Region | promoter |
| Transcript 3 Impact | promoter_insertion |
| Transcript 4 Gene Id | ENSG00000206077.15 |
| Transcript 4 Gene Name | ZDHHC11B |
| Transcript 4 Region | intron |
| Transcript 4 Impact | intronic_insertion |
| Transcript 5 Gene Id | ENSG00000206077.15 |
| Transcript 5 Gene Name | ZDHHC11B |
| Transcript 5 Region | intron |
| Transcript 5 Impact | intronic_insertion |
| Transcript 6 Gene Id | ENSG00000206077.15 |
| Transcript 6 Gene Name | ZDHHC11B |
| Transcript 6 Region | intron |
| Transcript 6 Impact | intronic_insertion |
| Transcript 7 Gene Id | ENSG00000206077.15 |
| Transcript 7 Gene Name | ZDHHC11B |
| Transcript 7 Region | intron |
| Transcript 7 Impact | intronic_insertion |
| Transcript 8 Gene Id | ENSG00000249908.2 |
| Transcript 8 Gene Name | BRD9P2 |
| Transcript 8 Region | intron |
| Transcript 8 Impact | intronic_insertion |
| AlphaGenome Analysis | |
| Window | chr5:702990-834062 |
| RNA-seq Change (±2kb) | Mean: -0.00025607715360820293 | Peak: 1.218994140625 |
| ATAC Change (±2kb) | Mean: 0.0004981886595487595 | Peak: 1.984372615814209 |
| Interpretation | RNA-seq: minimal change -1.1% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change 1.2% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D