| Basic Information ▶ | |
| VISDB ID | TVIS20021298 |
|---|---|
| Fusion Name | HPV-ATP6V0D1-DT integration |
| Validated | No |
| Curated Way | Curated |
| Method | HPV capture sequencing |
| Wet Assay | Yes |
| Sample ID | 17O011393.2 |
| Sample Name | New sample |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Cervical cancer |
| Disease Abbreviation | CC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 35968887 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2022 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | chr16 |
| Cytogenetic Band | q22.1 |
| Human Strand | + |
| Human Integration Location Type | intronic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 67498257 |
| Hg38 End | 67498257 |
| Junction Sequence | TTAGATCTGTTCCACTATCATATGCATTTTCATCCTCGTCCTCTGAAATGTTATCTCCTGTTTGTTTTTCTATTATAGCTGGGACTACAGGCGCACACTACCACGCCCCGCTAACTTTTTGTATTTTTAGTAGAGATGGGGT |
| Target Gene ▶ | |
| Target Gene | ATP6V0D1-DT, CTCF-DT |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Papillomavirus |
| Virus Subtype Name | HPV52 |
| Virus Genome Accession | X74481 |
| TaxonomyID | 10566 |
| Virus Abbreviation | HPV |
| Virus Genome | Human papillomavirus type 52 genomic DNA |
| Virus Genome Length | 7,942 bp |
| Virus Breakpoint1 | 930 |
| Virus Breakpoint2 | - |
| Virus Gene Name | E1 |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000656196.1, Transcript 2: ENST00000659360.1, Transcript 3: ENST00000748739.1, Transcript 4: ENST00000748740.1, Transcript 5: ENST00000635000.1, Transcript 6: ENST00000748475.1, Transcript 7: ENST00000748476.1, Transcript 8: ENST00000748477.1, Transcript 9: ENST00000748478.1 |
| Transcript 1 Gene Id | ENSG00000270049.5 |
| Transcript 1 Gene Name | ATP6V0D1-DT |
| Transcript 2 Gene Id | ENSG00000270049.5 |
| Transcript 2 Gene Name | ATP6V0D1-DT |
| Transcript 3 Gene Id | ENSG00000270049.5 |
| Transcript 3 Gene Name | ATP6V0D1-DT |
| Transcript 4 Gene Id | ENSG00000270049.5 |
| Transcript 4 Gene Name | ATP6V0D1-DT |
| Transcript 5 Gene Id | ENSG00000270049.5 |
| Transcript 5 Gene Name | ATP6V0D1-DT |
| Transcript 6 Gene Id | ENSG00000259804.2 |
| Transcript 6 Gene Name | CTCF-DT |
| Transcript 7 Gene Id | ENSG00000259804.2 |
| Transcript 7 Gene Name | CTCF-DT |
| Transcript 8 Gene Id | ENSG00000259804.2 |
| Transcript 8 Gene Name | CTCF-DT |
| Transcript 9 Gene Id | ENSG00000259804.2 |
| Transcript 9 Gene Name | CTCF-DT |
| AlphaGenome Analysis | |
| Window | chr16:67432721-67563793 |
| RNA-seq Change (±2kb) | Mean: -4.202259151497856e-05 | Peak: 0.2138671875 |
| ATAC Change (±2kb) | Mean: 0.0033982873428612947 | Peak: 8.61328125 |
| Interpretation | RNA-seq: minimal change -0.3% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: INCREASED 11.5% (REF=0.03, ALT=0.03) |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D