| Basic Information ▶ | |
| VISDB ID | TVIS20022298 |
|---|---|
| Fusion Name | HPV-EPB41L3 integration |
| Validated | No |
| Curated Way | Curated |
| Method | HPV capture sequencing |
| Wet Assay | Yes |
| Sample ID | D236604.3 |
| Sample Name | New sample |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Cervical cancer |
| Disease Abbreviation | CC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 35968887 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2022 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | chr18 |
| Cytogenetic Band | p11.31 |
| Human Strand | + |
| Human Integration Location Type | intronic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 5443153 |
| Hg38 End | 5443153 |
| Junction Sequence | gtgtcaggaaaaccaaacttattggggtcaggtaAATGTATTCTAAATACCCTGTATTGTAATCCTGATACTTTAGGAACTAATATTTTGTTATTGTTAGGTTTTTTAATAGGAAAATAGGGATGTCCAACAGCTTAAATTTTAATATTGACAATTGCCCTCTGAAATGATTGAACCAACTTACtctaccaattgagtaaataagtgctatagtttattattaaaccctaattctttgttaatctgaataggtgaaaaatg |
| Target Gene ▶ | |
| Target Gene | EPB41L3 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Papillomavirus |
| Virus Subtype Name | HPV16 |
| Virus Genome Accession | K02718 |
| TaxonomyID | 10566 |
| Virus Abbreviation | HPV |
| Virus Genome | Human papillomavirus type 16 (HPV16), complete genome |
| Virus Genome Length | 7,904 bp |
| Virus Breakpoint1 | 5769 |
| Virus Breakpoint2 | - |
| Virus Gene Name | L1 |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000082397.19 |
| Gene Name | EPB41L3 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000866142.1, Transcript 2: ENST00000544123.5, Transcript 3: ENST00000342933.7, Transcript 4: ENST00000866152.1, Transcript 5: ENST00000866148.1, Transcript 6: ENST00000971994.1, Transcript 7: ENST00000542652.6, Transcript 8: ENST00000866158.1, Transcript 9: ENST00000866156.1, Transcript 10: ENST00000341928.7, Transcript 11: ENST00000936514.1, Transcript 12: ENST00000971998.1, Transcript 13: ENST00000866149.1, Transcript 14: ENST00000866150.1, Transcript 15: ENST00000971993.1, Transcript 16: ENST00000866147.1, Transcript 17: ENST00000936513.1, Transcript 18: ENST00000971990.1, Transcript 19: ENST00000866146.1, Transcript 20: ENST00000866145.1, Transcript 21: ENST00000936512.1, Transcript 22: ENST00000866143.1, Transcript 23: ENST00000972001.1, Transcript 24: ENST00000971999.1, Transcript 25: ENST00000971997.1, Transcript 26: ENST00000971996.1, Transcript 27: ENST00000971995.1, Transcript 28: ENST00000971992.1, Transcript 29: ENST00000971991.1, Transcript 30: ENST00000972007.1, Transcript 31: ENST00000936515.1, Transcript 32: ENST00000972004.1, Transcript 33: ENST00000866157.1, Transcript 34: ENST00000972003.1, Transcript 35: ENST00000866155.1, Transcript 36: ENST00000866154.1, Transcript 37: ENST00000866151.1, Transcript 38: ENST00000972002.1, Transcript 39: ENST00000866153.1, Transcript 40: ENST00000972005.1, Transcript 41: ENST00000972000.1, Transcript 42: ENST00000400111.8, Transcript 43: ENST00000637651.1, Transcript 44: ENST00000972006.1, Transcript 45: ENST00000540638.6, Transcript 46: ENST00000545076.5, Transcript 47: ENST00000866159.1, Transcript 48: ENST00000866160.1, Transcript 49: ENST00000866144.1, Transcript 50: ENST00000584670.1 |
| SpliceAI Score | |
| Delta Scores | Acceptor Gain: 0.020 | Acceptor Loss: 0.010 | Donor Gain: 0.010 | Donor Loss: 0.000 |
| Delta Score Max | 0.020 |
| Delta Position at Max | -1206 |
| Delta Score Flag | LOW |
| Gene | EPB41L3 |
| AlphaGenome Analysis | |
| Chromosome | chr18 |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D