| Basic Information ▶ | |
| VISDB ID | TVIS20024287 |
|---|---|
| Fusion Name | HPV-chr19:35192209 integration |
| Validated | No |
| Curated Way | Curated |
| Method | EBV capture sequencing, followed by Viral Integration Pathway Analysis (VIPA) pipeline |
| Wet Assay | No |
| Sample ID | SRR4003636.3 |
| Sample Name | SRA315538 |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Cervical cancer |
| Disease Abbreviation | CC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 35968887 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2022 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | chr19 |
| Cytogenetic Band | q13.12 |
| Human Strand | + |
| Human Integration Location Type | intergenic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 35192209 |
| Hg38 End | 35192209 |
| Junction Sequence | cagacgaaaatgcaacagacACAGGGTCGGATATGGTAGATTTTATTGATACACAAGGAACATTTTGTAGATTACTTTTAATCTACAAATTTCCTTAAATTTAAAGAGTTTCTTGTTGAgagcatatagttaagtgaatt |
| Target Gene ▶ | |
| Target Gene | - |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Papillomavirus |
| Virus Subtype Name | HPV18 |
| Virus Genome Accession | X05015 |
| TaxonomyID | 10566 |
| Virus Abbreviation | HPV |
| Virus Genome | Human papillomavirus type 18 E6, E7, E1, E2, E4, E5, L1 & L2 genes |
| Virus Genome Length | 7,857 bp |
| Virus Breakpoint1 | 1087 |
| Virus Breakpoint2 | - |
| Virus Gene Name | E1 |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Region | intergenic |
| Impact | NA |
| AlphaGenome Analysis | |
| Window | chr19:35126673-35257745 |
| RNA-seq Change (±2kb) | Mean: -2.4619480427645613e-06 | Peak: 0.129638671875 |
| ATAC Change (±2kb) | Mean: -0.00044862504000775516 | Peak: 0.819580078125 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: no signal in region (REF≈0, ALT≈0) |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D