| Basic Information ▶ | |
| VISDB ID | TVIS20024701 |
|---|---|
| Fusion Name | HPV-chr9:36567219 integration |
| Validated | No |
| Curated Way | Curated |
| Method | EBV capture sequencing, followed by Viral Integration Pathway Analysis (VIPA) pipeline |
| Wet Assay | No |
| Sample ID | SRR1611079.6 |
| Sample Name | SRA189003 |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Cervical cancer |
| Disease Abbreviation | CC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 35968887 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2022 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | chr9 |
| Cytogenetic Band | p13.2 |
| Human Strand | + |
| Human Integration Location Type | intergenic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 36567219 |
| Hg38 End | 36567219 |
| Junction Sequence | ctctcctgcctttttccatcctgtgctccacccaactggcctttctcCACGGTGACTTGTGTTTTCTCGCCCCCTGCTTGTTTCCGGTGTCTGGCTCTGATCTTGGTCGCTGGATAGTCGTCTGTGTTTCTTCGGTGCCCAAGGCGAcggct |
| Target Gene ▶ | |
| Target Gene | - |
| Nearby Gene | MELK |
| Distance | 5643 |
| Virus Information ▶ | |
| Virus Name | Human Papillomavirus |
| Virus Subtype Name | HPV16 |
| Virus Genome Accession | K02718 |
| TaxonomyID | 10566 |
| Virus Abbreviation | HPV |
| Virus Genome | Human papillomavirus type 16 (HPV16), complete genome |
| Virus Genome Length | 7,904 bp |
| Virus Breakpoint1 | 3501 |
| Virus Breakpoint2 | - |
| Virus Gene Name | E2,E4 |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Region | intergenic |
| Impact | NA |
| AlphaGenome Analysis | |
| Window | chr9:36501683-36632755 |
| RNA-seq Change (±2kb) | Mean: 0.0001497230987297371 | Peak: 0.020529747009277344 |
| ATAC Change (±2kb) | Mean: 0.009342878125607967 | Peak: 9.0625 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: INCREASED 25.9% (REF=0.04, ALT=0.05) |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D