| Basic Information ▶ | |
| VISDB ID | TVIS20024864 |
|---|---|
| Fusion Name | HPV-RNF34 integration |
| Validated | No |
| Curated Way | Curated |
| Method | EBV capture sequencing, followed by Viral Integration Pathway Analysis (VIPA) pipeline |
| Wet Assay | No |
| Sample ID | SRR1611094.178 |
| Sample Name | SRA189003 |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Cervical cancer |
| Disease Abbreviation | CC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 35968887 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2022 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | chr12 |
| Cytogenetic Band | q24.31 |
| Human Strand | + |
| Human Integration Location Type | intronic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 121413665 |
| Hg38 End | 121413665 |
| Junction Sequence | CTATGTTTCAAGACACTGAGGAAAAACCACGAACATTGCAcCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCCC |
| Target Gene ▶ | |
| Target Gene | RNF34 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Papillomavirus |
| Virus Subtype Name | HPV33 |
| Virus Genome Accession | M12732 |
| TaxonomyID | 10566 |
| Virus Abbreviation | HPV |
| Virus Genome | Human papillomavirus type 33, complete genome |
| Virus Genome Length | 7909 bp |
| Virus Breakpoint1 | 146 |
| Virus Breakpoint2 | - |
| Virus Gene Name | E6 |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000170633.18 |
| Gene Name | RNF34 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000964569.1, Transcript 2: ENST00000613529.4, Transcript 3: ENST00000867130.1, Transcript 4: ENST00000867133.1, Transcript 5: ENST00000867131.1, Transcript 6: ENST00000917689.1, Transcript 7: ENST00000361234.10, Transcript 8: ENST00000392465.7, Transcript 9: ENST00000556562.1, Transcript 10: ENST00000553407.5, Transcript 11: ENST00000554606.5, Transcript 12: ENST00000392464.3, Transcript 13: ENST00000555076.1, Transcript 14: ENST00000554868.1, Transcript 15: ENST00000557402.1 |
| SpliceAI Score | |
| Delta Scores | Acceptor Gain: 0.000 | Acceptor Loss: 0.000 | Donor Gain: 0.020 | Donor Loss: 0.000 |
| Delta Score Max | 0.020 |
| Delta Position at Max | 1197 |
| Delta Score Flag | LOW |
| Gene | RNF34 |
| AlphaGenome Analysis | |
| Chromosome | chr12 |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D