| Basic Information ▶ | |
| VISDB ID | TVIS20033623 |
|---|---|
| Fusion Name | HPV-ENSG00000289219 integration |
| Validated | No |
| Curated Way | Curated |
| Method | High-throughput Viral Integration Detection method |
| Wet Assay | Yes |
| Sample ID | - |
| Sample Name | S025 |
| Sample Type | Tumor |
| Age | 57 = 59; >57 = 50 |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Oropharyngeal squamous cell carcinoma |
| Disease Abbreviation | OPSCC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 38279874 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2024 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr3 |
| Cytogenetic Band | q29 |
| Human Strand | - |
| Human Integration Location Type | intronic |
| Hg19 Start | 195867952 |
| Hg19 End | 195867952 |
| Hg38 Start | 196141081 |
| Hg38 End | 196141081 |
| Junction Sequence | CTGAAGTGGAAACTCAGCAGATGTTACAGGTAGAAGGGCGCCATGAGACTGAAACACCATGTAGTCAGTATAGTGGTGGAAGTGGGGGTGGTTGCAGTCAGTACAGTAGTGGAAGTGGGGGAGAGGGTGCCAGTGGCCTGGACCTGCTTCCCCTCCCCGGGTGCCTCCGCGGGAGCCCCTGTCCCCTCAAGGCTCGAGG |
| Target Gene ▶ | |
| Target Gene | ENSG00000289219 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Papillomavirus |
| Virus Subtype Name | HPV16 |
| Virus Genome Accession | AF534061 |
| TaxonomyID | 10566 |
| Virus Abbreviation | HPV |
| Virus Genome | Human papillomavirus type 16 East Asian type, complete genome |
| Virus Genome Length | 7905 bp |
| Virus Breakpoint1 | 1401 |
| Virus Breakpoint2 | - |
| Virus Gene Name | HpV16gp3_E1 |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Transcript | Transcript 1: ENST00000745236.1, Transcript 2: ENST00000745237.1, Transcript 3: ENST00000745239.1, Transcript 4: ENST00000745238.1, Transcript 5: ENST00000659409.3, Transcript 6: ENST00000654470.3, Transcript 7: ENST00000670584.3, Transcript 8: ENST00000744823.1, Transcript 9: ENST00000457079.4, Transcript 10: ENST00000662916.2, Transcript 11: ENST00000669905.3, Transcript 12: ENST00000744821.1, Transcript 13: ENST00000744822.1, Transcript 14: ENST00000662113.2, Transcript 15: ENST00000744827.1, Transcript 16: ENST00000744824.1, Transcript 17: ENST00000702140.2, Transcript 18: ENST00000744825.1, Transcript 19: ENST00000744814.1, Transcript 20: ENST00000744826.1, Transcript 21: ENST00000744816.1, Transcript 22: ENST00000744849.1, Transcript 23: ENST00000744845.1, Transcript 24: ENST00000689269.2, Transcript 25: ENST00000744828.1, Transcript 26: ENST00000744846.1, Transcript 27: ENST00000744830.1, Transcript 28: ENST00000744829.1, Transcript 29: ENST00000744819.1, Transcript 30: ENST00000744815.1, Transcript 31: ENST00000744831.1, Transcript 32: ENST00000744832.1, Transcript 33: ENST00000744817.1, Transcript 34: ENST00000687908.1, Transcript 35: ENST00000744818.1 |
| Transcript 1 Gene Id | ENSG00000289219.2 |
| Transcript 1 Gene Name | ENSG00000289219 |
| Transcript 1 Region | intron |
| Transcript 1 Impact | intronic_insertion |
| Transcript 2 Gene Id | ENSG00000289219.2 |
| Transcript 2 Gene Name | ENSG00000289219 |
| Transcript 2 Region | intron |
| Transcript 2 Impact | intronic_insertion |
| Transcript 3 Gene Id | ENSG00000289219.2 |
| Transcript 3 Gene Name | ENSG00000289219 |
| Transcript 3 Region | intron |
| Transcript 3 Impact | intronic_insertion |
| Transcript 4 Gene Id | ENSG00000289219.2 |
| Transcript 4 Gene Name | ENSG00000289219 |
| Transcript 4 Region | intron |
| Transcript 4 Impact | intronic_insertion |
| Transcript 5 Gene Id | ENSG00000224652.5 |
| Transcript 5 Gene Name | LINC00885 |
| Transcript 5 Region | promoter |
| Transcript 5 Impact | promoter_insertion |
| Transcript 6 Gene Id | ENSG00000224652.5 |
| Transcript 6 Gene Name | LINC00885 |
| Transcript 6 Region | promoter |
| Transcript 6 Impact | promoter_insertion |
| Transcript 7 Gene Id | ENSG00000224652.5 |
| Transcript 7 Gene Name | LINC00885 |
| Transcript 7 Region | promoter |
| Transcript 7 Impact | promoter_insertion |
| Transcript 8 Gene Id | ENSG00000224652.5 |
| Transcript 8 Gene Name | LINC00885 |
| Transcript 8 Region | promoter |
| Transcript 8 Impact | promoter_insertion |
| Transcript 9 Gene Id | ENSG00000224652.5 |
| Transcript 9 Gene Name | LINC00885 |
| Transcript 9 Region | promoter |
| Transcript 9 Impact | promoter_insertion |
| Transcript 10 Gene Id | ENSG00000224652.5 |
| Transcript 10 Gene Name | LINC00885 |
| Transcript 10 Region | promoter |
| Transcript 10 Impact | promoter_insertion |
| Transcript 11 Gene Id | ENSG00000224652.5 |
| Transcript 11 Gene Name | LINC00885 |
| Transcript 11 Region | promoter |
| Transcript 11 Impact | promoter_insertion |
| Transcript 12 Gene Id | ENSG00000224652.5 |
| Transcript 12 Gene Name | LINC00885 |
| Transcript 12 Region | promoter |
| Transcript 12 Impact | promoter_insertion |
| Transcript 13 Gene Id | ENSG00000224652.5 |
| Transcript 13 Gene Name | LINC00885 |
| Transcript 13 Region | promoter |
| Transcript 13 Impact | promoter_insertion |
| Transcript 14 Gene Id | ENSG00000224652.5 |
| Transcript 14 Gene Name | LINC00885 |
| Transcript 14 Region | promoter |
| Transcript 14 Impact | promoter_insertion |
| Transcript 15 Gene Id | ENSG00000224652.5 |
| Transcript 15 Gene Name | LINC00885 |
| Transcript 15 Region | promoter |
| Transcript 15 Impact | promoter_insertion |
| Transcript 16 Gene Id | ENSG00000224652.5 |
| Transcript 16 Gene Name | LINC00885 |
| Transcript 16 Region | promoter |
| Transcript 16 Impact | promoter_insertion |
| Transcript 17 Gene Id | ENSG00000224652.5 |
| Transcript 17 Gene Name | LINC00885 |
| Transcript 17 Region | promoter |
| Transcript 17 Impact | promoter_insertion |
| Transcript 18 Gene Id | ENSG00000224652.5 |
| Transcript 18 Gene Name | LINC00885 |
| Transcript 18 Region | promoter |
| Transcript 18 Impact | promoter_insertion |
| Transcript 19 Gene Id | ENSG00000224652.5 |
| Transcript 19 Gene Name | LINC00885 |
| Transcript 19 Region | promoter |
| Transcript 19 Impact | promoter_insertion |
| Transcript 20 Gene Id | ENSG00000224652.5 |
| Transcript 20 Gene Name | LINC00885 |
| Transcript 20 Region | promoter |
| Transcript 20 Impact | promoter_insertion |
| Transcript 21 Gene Id | ENSG00000224652.5 |
| Transcript 21 Gene Name | LINC00885 |
| Transcript 21 Region | promoter |
| Transcript 21 Impact | promoter_insertion |
| Transcript 22 Gene Id | ENSG00000224652.5 |
| Transcript 22 Gene Name | LINC00885 |
| Transcript 22 Region | promoter |
| Transcript 22 Impact | promoter_insertion |
| Transcript 23 Gene Id | ENSG00000224652.5 |
| Transcript 23 Gene Name | LINC00885 |
| Transcript 23 Region | promoter |
| Transcript 23 Impact | promoter_insertion |
| Transcript 24 Gene Id | ENSG00000224652.5 |
| Transcript 24 Gene Name | LINC00885 |
| Transcript 24 Region | promoter |
| Transcript 24 Impact | promoter_insertion |
| Transcript 25 Gene Id | ENSG00000224652.5 |
| Transcript 25 Gene Name | LINC00885 |
| Transcript 25 Region | promoter |
| Transcript 25 Impact | promoter_insertion |
| Transcript 26 Gene Id | ENSG00000224652.5 |
| Transcript 26 Gene Name | LINC00885 |
| Transcript 26 Region | promoter |
| Transcript 26 Impact | promoter_insertion |
| Transcript 27 Gene Id | ENSG00000224652.5 |
| Transcript 27 Gene Name | LINC00885 |
| Transcript 27 Region | promoter |
| Transcript 27 Impact | promoter_insertion |
| Transcript 28 Gene Id | ENSG00000224652.5 |
| Transcript 28 Gene Name | LINC00885 |
| Transcript 28 Region | promoter |
| Transcript 28 Impact | promoter_insertion |
| Transcript 29 Gene Id | ENSG00000224652.5 |
| Transcript 29 Gene Name | LINC00885 |
| Transcript 29 Region | promoter |
| Transcript 29 Impact | promoter_insertion |
| Transcript 30 Gene Id | ENSG00000224652.5 |
| Transcript 30 Gene Name | LINC00885 |
| Transcript 30 Region | promoter |
| Transcript 30 Impact | promoter_insertion |
| Transcript 31 Gene Id | ENSG00000224652.5 |
| Transcript 31 Gene Name | LINC00885 |
| Transcript 31 Region | promoter |
| Transcript 31 Impact | promoter_insertion |
| Transcript 32 Gene Id | ENSG00000224652.5 |
| Transcript 32 Gene Name | LINC00885 |
| Transcript 32 Region | promoter |
| Transcript 32 Impact | promoter_insertion |
| Transcript 33 Gene Id | ENSG00000224652.5 |
| Transcript 33 Gene Name | LINC00885 |
| Transcript 33 Region | promoter |
| Transcript 33 Impact | promoter_insertion |
| Transcript 34 Gene Id | ENSG00000224652.5 |
| Transcript 34 Gene Name | LINC00885 |
| Transcript 34 Region | promoter |
| Transcript 34 Impact | promoter_insertion |
| Transcript 35 Gene Id | ENSG00000224652.5 |
| Transcript 35 Gene Name | LINC00885 |
| Transcript 35 Region | promoter |
| Transcript 35 Impact | promoter_insertion |
| AlphaGenome Analysis | |
| Window | chr3:196075545-196206617 |
| RNA-seq Change (±2kb) | Mean: -0.00031269408646039665 | Peak: 0.61767578125 |
| ATAC Change (±2kb) | Mean: 0.006597399711608887 | Peak: 20.25 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: INCREASED 10.7% (REF=0.06, ALT=0.07) |
| Visualization | |