| Basic Information ▶ | |
| VISDB ID | TVIS20035841 |
|---|---|
| Fusion Name | HPV-MT-ATP6 integration |
| Validated | No |
| Curated Way | Curated |
| Method | High-throughput Viral Integration Detection method |
| Wet Assay | Yes |
| Sample ID | - |
| Sample Name | S094 |
| Sample Type | Tumor |
| Age | 57 = 59; >57 = 50 |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Oropharyngeal squamous cell carcinoma |
| Disease Abbreviation | OPSCC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 38279874 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2024 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chrM |
| Cytogenetic Band | 0 |
| Human Strand | + |
| Human Integration Location Type | intergenic |
| Hg19 Start | 9144 |
| Hg19 End | 9144 |
| Hg38 Start | 9143 |
| Hg38 End | 9143 |
| Junction Sequence | ATCTCAGGCTATGTAGAGGTAGATGAGGTGGTGGGTGTAGCTTTTCGTTTTCCTAATGTAAATTTTGGTTTGGCCTTAATCCAAGCCTACGTTTTCACACTTCTAGTAAGCCTCTACCTGCACGACAACACATAATGACCCAATACCATCGAGAA |
| Target Gene ▶ | |
| Target Gene | MT-ATP6 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Papillomavirus |
| Virus Subtype Name | HPV16 |
| Virus Genome Accession | AF534061 |
| TaxonomyID | 10566 |
| Virus Abbreviation | HPV |
| Virus Genome | Human papillomavirus type 16 East Asian type, complete genome |
| Virus Genome Length | 7905 bp |
| Virus Breakpoint1 | 7063 |
| Virus Breakpoint2 | - |
| Virus Gene Name | HpV16gp8_L1 |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Transcript | Transcript 1: ENST00000387416.2, Transcript 2: ENST00000361899.2, Transcript 3: ENST00000362079.2, Transcript 4: ENST00000387429.1, Transcript 5: ENST00000361227.2, Transcript 6: ENST00000387439.1, Transcript 7: ENST00000361335.1, Transcript 8: ENST00000361381.2 |
| Transcript 1 Gene Id | ENSG00000210151.2 |
| Transcript 1 Gene Name | MT-TS1 |
| Transcript 1 Region | promoter |
| Transcript 1 Impact | promoter_insertion |
| Transcript 2 Gene Id | ENSG00000198899.2 |
| Transcript 2 Gene Name | MT-ATP6 |
| Transcript 2 Region | CDS |
| Transcript 2 Impact | stop_gained |
| Transcript 2 Frameshift | True |
| Transcript 2 Stop Gained | True |
| Transcript 2 Protein Change From Aa0 | 47 |
| Transcript 3 Gene Id | ENSG00000198938.2 |
| Transcript 3 Gene Name | MT-CO3 |
| Transcript 3 Region | promoter |
| Transcript 3 Impact | promoter_insertion |
| Transcript 4 Gene Id | ENSG00000210164.1 |
| Transcript 4 Gene Name | MT-TG |
| Transcript 4 Region | promoter |
| Transcript 4 Impact | promoter_insertion |
| Transcript 5 Gene Id | ENSG00000198840.2 |
| Transcript 5 Gene Name | MT-ND3 |
| Transcript 5 Region | promoter |
| Transcript 5 Impact | promoter_insertion |
| Transcript 6 Gene Id | ENSG00000210174.1 |
| Transcript 6 Gene Name | MT-TR |
| Transcript 6 Region | promoter |
| Transcript 6 Impact | promoter_insertion |
| Transcript 7 Gene Id | ENSG00000212907.2 |
| Transcript 7 Gene Name | MT-ND4L |
| Transcript 7 Region | promoter |
| Transcript 7 Impact | promoter_insertion |
| Transcript 8 Gene Id | ENSG00000198886.2 |
| Transcript 8 Gene Name | MT-ND4 |
| Transcript 8 Region | promoter |
| Transcript 8 Impact | promoter_insertion |
| AlphaGenome Analysis | |
| Chromosome | chrM |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D