Virus Integration Site Database Data Release 2.0

Details for VISDB ID: TVIS20049538

Genomic Region Visualization (IGV)

Basic Information ▶
VISDB IDTVIS20049538
Fusion NameHPV-CSTPP1 integration
ValidatedNo
Curated WayCurated
MethodHigh-throughput Viral Integration Detection method
Wet AssayYes
Sample ID-
Sample NameS094
Sample TypeTumor
Age57 = 59; >57 = 50
Gender-
Disease Information ▶
Disease NameOropharyngeal squamous cell carcinoma
Disease AbbreviationOPSCC
CancerYes
Literature ▶
PubMed ID38279874
JournalClinical and Translational Medicine
Published Year2024
Human Genome ▶
Human Genome Version DescriptionGRCh37/hg19
Human Genome RefSeq AccessionGCF_000001405.13
Human Chromosomechr11
Cytogenetic Bandp11.2
Human Strand+
Human Integration Location Typeexonic
Hg19 Start47159543
Hg19 End47159543
Hg38 Start47137992
Hg38 End47137992
Junction SequenceGAGGTTGCGGTGAGCCGAGATCACGCCATTGCACGCCAGCCTGTGCAACAGAGCAAGACAGTCTCAAAAAAGAAAAAAAAAACAAAAACAGGCGAGAGTCAGTACAGTAGTGGAAGTGGGGGAGAGGGTGTTAGTGAAAGAC
Target Gene ▶
Target GeneCSTPP1
Nearby Gene-
Distance-
Virus Information ▶
Virus NameHuman Papillomavirus
Virus Subtype NameHPV16
Virus Genome AccessionAF534061
TaxonomyID10566
Virus AbbreviationHPV
Virus GenomeHuman papillomavirus type 16 East Asian type, complete genome
Virus Genome Length7905 bp
Virus Breakpoint11368
Virus Breakpoint2-
Virus Gene NameHpV16gp3_E1
Virus Region Type-
Integrated Virus Sequence-
ViMIC ID-
Predicted VIS Effect ▶
Gene IdENSG00000149179.15
Gene NameCSTPP1
TranscriptTranscript 1: ENST00000528488.5, Transcript 2: ENST00000940907.1, Transcript 3: ENST00000525279.5, Transcript 4: ENST00000527234.5, Transcript 5: ENST00000378618.6, Transcript 6: ENST00000532840.5, Transcript 7: ENST00000940908.1, Transcript 8: ENST00000278460.12, Transcript 9: ENST00000395460.6, Transcript 10: ENST00000378615.7, Transcript 11: ENST00000525895.5, Transcript 12: ENST00000527667.5, Transcript 13: ENST00000527784.5, Transcript 14: ENST00000527268.5, Transcript 15: ENST00000534249.5, Transcript 16: ENST00000526827.1, Transcript 17: ENST00000529980.5
Transcript 1 Regionintron
Transcript 1 Impactintronic_insertion
Transcript 2 Regionintron
Transcript 2 Impactintronic_insertion
Transcript 3 Regionintron
Transcript 3 Impactintronic_insertion
Transcript 4 Regionintron
Transcript 4 Impactintronic_insertion
Transcript 5 Regionintron
Transcript 5 Impactintronic_insertion
Transcript 6 Regionexon_non_coding
Transcript 6 Impactnoncoding_exon_insertion
Transcript 7 Regionintron
Transcript 7 Impactintronic_insertion
Transcript 8 Regionintron
Transcript 8 Impactintronic_insertion
Transcript 9 Regionintron
Transcript 9 Impactintronic_insertion
Transcript 10 Regionintron
Transcript 10 Impactintronic_insertion
Transcript 11 Regionintron
Transcript 11 Impactintronic_insertion
Transcript 12 Regionintron
Transcript 12 Impactintronic_insertion
Transcript 13 Regionintron
Transcript 13 Impactintronic_insertion
Transcript 14 Regionintron
Transcript 14 Impactintronic_insertion
Transcript 15 Regionintron
Transcript 15 Impactintronic_insertion
Transcript 16 Regionintron
Transcript 16 Impactintronic_insertion
Transcript 17 Regionintron
Transcript 17 Impactintronic_insertion
SpliceAI Score
Delta ScoresAcceptor Gain: 0.010 | Acceptor Loss: 0.010 | Donor Gain: 0.000 | Donor Loss: 0.020
Delta Score Max0.020
Delta Position at Max-432
Delta Score FlagLOW
GeneC11orf49
AlphaGenome Analysis
Windowchr11:47072456-47203528
RNA-seq Change (±2kb)Mean: 0.0006659848149865866 | Peak: 0.78125
ATAC Change (±2kb)Mean: 0.011876177042722702 | Peak: 17.874637603759766
InterpretationRNA-seq: minimal change 5.1% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: INCREASED 51.7% (REF=0.02, ALT=0.03)
Visualization
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