Virus Integration Site Database Data Release 2.0

Details for VISDB ID: TVIS20066867

Genomic Region Visualization (IGV)

Basic Information ▶
VISDB IDTVIS20066867
Fusion NameHPV-PPM1A integration
ValidatedNo
Curated WayCurated
MethodHigh-throughput Viral Integration Detection method
Wet AssayYes
Sample ID-
Sample NameS102
Sample TypeTumor
Age57 = 59; >57 = 50
Gender-
Disease Information ▶
Disease NameOropharyngeal squamous cell carcinoma
Disease AbbreviationOPSCC
CancerYes
Literature ▶
PubMed ID38279874
JournalClinical and Translational Medicine
Published Year2024
Human Genome ▶
Human Genome Version DescriptionGRCh37/hg19
Human Genome RefSeq AccessionGCF_000001405.13
Human Chromosomechr14
Cytogenetic Bandq23.1
Human Strand+
Human Integration Location Typeintronic
Hg19 Start60744927
Hg19 End60744927
Hg38 Start60278209
Hg38 End60278209
Junction SequenceACTTCAGTATTGCCATACCCGCTGTCTTCGCTTTCAAATAATCTCCTTTTTGCAGCTCTACTTTGTTTTTCCTCTCTTAACCACTCTCTTTTAAGCCTTGATTGGTTTTGCCCTACACATGTGCAGCCTATGTCTTGGCC
Target Gene ▶
Target GenePPM1A
Nearby Gene-
Distance-
Virus Information ▶
Virus NameHuman Papillomavirus
Virus Subtype NameHPV16
Virus Genome AccessionHQ644236
TaxonomyID10566
Virus AbbreviationHPV
Virus GenomeHuman papillomavirus type 16 isolate AS411, complete genome
Virus Genome Length7905bp
Virus Breakpoint11209
Virus Breakpoint2-
Virus Gene NameHpV16gp3_E1
Virus Region Type-
Integrated Virus Sequence-
ViMIC ID-
Predicted VIS Effect ▶
Gene IdENSG00000100614.19
Gene NamePPM1A
TranscriptTranscript 1: ENST00000325642.7, Transcript 2: ENST00000531143.6, Transcript 3: ENST00000532036.2, Transcript 4: ENST00000893048.1, Transcript 5: ENST00000893046.1, Transcript 6: ENST00000953911.1, Transcript 7: ENST00000893047.1, Transcript 8: ENST00000893041.1, Transcript 9: ENST00000893050.1, Transcript 10: ENST00000893049.1, Transcript 11: ENST00000893052.1, Transcript 12: ENST00000893051.1, Transcript 13: ENST00000893054.1, Transcript 14: ENST00000893055.1, Transcript 15: ENST00000893056.1, Transcript 16: ENST00000893057.1, Transcript 17: ENST00000893058.1, Transcript 18: ENST00000893059.1, Transcript 19: ENST00000893043.1, Transcript 20: ENST00000893044.1, Transcript 21: ENST00000893062.1, Transcript 22: ENST00000893061.1, Transcript 23: ENST00000953919.1, Transcript 24: ENST00000893063.1, Transcript 25: ENST00000893064.1, Transcript 26: ENST00000893065.1, Transcript 27: ENST00000893066.1, Transcript 28: ENST00000953914.1, Transcript 29: ENST00000893042.1, Transcript 30: ENST00000953912.1, Transcript 31: ENST00000893068.1, Transcript 32: ENST00000953918.1, Transcript 33: ENST00000893067.1, Transcript 34: ENST00000953922.1, Transcript 35: ENST00000953920.1, Transcript 36: ENST00000953921.1, Transcript 37: ENST00000893045.1, Transcript 38: ENST00000893076.1, Transcript 39: ENST00000953924.1, Transcript 40: ENST00000893070.1, Transcript 41: ENST00000893071.1, Transcript 42: ENST00000893072.1, Transcript 43: ENST00000893069.1, Transcript 44: ENST00000395076.9, Transcript 45: ENST00000925842.1, Transcript 46: ENST00000893073.1, Transcript 47: ENST00000925843.1, Transcript 48: ENST00000893074.1, Transcript 49: ENST00000893075.1, Transcript 50: ENST00000953925.1, Transcript 51: ENST00000953926.1, Transcript 52: ENST00000893078.1, Transcript 53: ENST00000893077.1, Transcript 54: ENST00000925844.1, Transcript 55: ENST00000893079.1, Transcript 56: ENST00000953927.1, Transcript 57: ENST00000953929.1, Transcript 58: ENST00000953928.1, Transcript 59: ENST00000953930.1, Transcript 60: ENST00000893080.1, Transcript 61: ENST00000953915.1, Transcript 62: ENST00000893081.1, Transcript 63: ENST00000893082.1, Transcript 64: ENST00000953931.1, Transcript 65: ENST00000893053.1, Transcript 66: ENST00000953932.1, Transcript 67: ENST00000893083.1, Transcript 68: ENST00000893084.1, Transcript 69: ENST00000925845.1, Transcript 70: ENST00000953933.1, Transcript 71: ENST00000953934.1, Transcript 72: ENST00000953935.1, Transcript 73: ENST00000953936.1, Transcript 74: ENST00000953939.1, Transcript 75: ENST00000953937.1, Transcript 76: ENST00000953938.1, Transcript 77: ENST00000953941.1, Transcript 78: ENST00000953940.1, Transcript 79: ENST00000953916.1, Transcript 80: ENST00000953944.1, Transcript 81: ENST00000953942.1, Transcript 82: ENST00000953945.1, Transcript 83: ENST00000953943.1, Transcript 84: ENST00000325658.3, Transcript 85: ENST00000953946.1, Transcript 86: ENST00000953949.1, Transcript 87: ENST00000953948.1, Transcript 88: ENST00000953947.1, Transcript 89: ENST00000953923.1, Transcript 90: ENST00000953917.1, Transcript 91: ENST00000893085.1, Transcript 92: ENST00000953950.1, Transcript 93: ENST00000893086.1, Transcript 94: ENST00000953951.1, Transcript 95: ENST00000528241.2, Transcript 96: ENST00000893087.1, Transcript 97: ENST00000893060.1, Transcript 98: ENST00000925846.1, Transcript 99: ENST00000525399.2, Transcript 100: ENST00000953913.1, Transcript 101: ENST00000953952.1, Transcript 102: ENST00000531937.1, Transcript 103: ENST00000925847.1, Transcript 104: ENST00000893088.1, Transcript 105: ENST00000893089.1, Transcript 106: ENST00000893090.1, Transcript 107: ENST00000893091.1
Transcript 1 Regionintron
Transcript 1 Impactintronic_insertion
Transcript 2 Regionintron
Transcript 2 Impactintronic_insertion
Transcript 3 Regionintron
Transcript 3 Impactintronic_insertion
Transcript 4 Regionintron
Transcript 4 Impactintronic_insertion
Transcript 5 Regionintron
Transcript 5 Impactintronic_insertion
Transcript 6 Regionintron
Transcript 6 Impactintronic_insertion
Transcript 7 Regionintron
Transcript 7 Impactintronic_insertion
Transcript 8 Regionintron
Transcript 8 Impactintronic_insertion
Transcript 9 Regionintron
Transcript 9 Impactintronic_insertion
Transcript 10 Regionintron
Transcript 10 Impactintronic_insertion
Transcript 11 Regionintron
Transcript 11 Impactintronic_insertion
Transcript 12 Regionintron
Transcript 12 Impactintronic_insertion
Transcript 13 Regionintron
Transcript 13 Impactintronic_insertion
Transcript 14 Regionintron
Transcript 14 Impactintronic_insertion
Transcript 15 Regionintron
Transcript 15 Impactintronic_insertion
Transcript 16 Regionintron
Transcript 16 Impactintronic_insertion
Transcript 17 Regionintron
Transcript 17 Impactintronic_insertion
Transcript 18 Regionintron
Transcript 18 Impactintronic_insertion
Transcript 19 Regionintron
Transcript 19 Impactintronic_insertion
Transcript 20 Regionintron
Transcript 20 Impactintronic_insertion
Transcript 21 Regionintron
Transcript 21 Impactintronic_insertion
Transcript 22 Regionintron
Transcript 22 Impactintronic_insertion
Transcript 23 Regionintron
Transcript 23 Impactintronic_insertion
Transcript 24 Regionintron
Transcript 24 Impactintronic_insertion
Transcript 25 Regionintron
Transcript 25 Impactintronic_insertion
Transcript 26 Regionintron
Transcript 26 Impactintronic_insertion
Transcript 27 Regionintron
Transcript 27 Impactintronic_insertion
Transcript 28 Regionintron
Transcript 28 Impactintronic_insertion
Transcript 29 Regionintron
Transcript 29 Impactintronic_insertion
Transcript 30 Regionintron
Transcript 30 Impactintronic_insertion
Transcript 31 Regionintron
Transcript 31 Impactintronic_insertion
Transcript 32 Regionintron
Transcript 32 Impactintronic_insertion
Transcript 33 Regionintron
Transcript 33 Impactintronic_insertion
Transcript 34 Regionintron
Transcript 34 Impactintronic_insertion
Transcript 35 Regionintron
Transcript 35 Impactintronic_insertion
Transcript 36 Regionintron
Transcript 36 Impactintronic_insertion
Transcript 37 Regionintron
Transcript 37 Impactintronic_insertion
Transcript 38 Regionintron
Transcript 38 Impactintronic_insertion
Transcript 39 Regionintron
Transcript 39 Impactintronic_insertion
Transcript 40 Regionintron
Transcript 40 Impactintronic_insertion
Transcript 41 Regionintron
Transcript 41 Impactintronic_insertion
Transcript 42 Regionintron
Transcript 42 Impactintronic_insertion
Transcript 43 Regionintron
Transcript 43 Impactintronic_insertion
Transcript 44 Regionintron
Transcript 44 Impactintronic_insertion
Transcript 45 Regionintron
Transcript 45 Impactintronic_insertion
Transcript 46 Regionintron
Transcript 46 Impactintronic_insertion
Transcript 47 Regionintron
Transcript 47 Impactintronic_insertion
Transcript 48 Regionintron
Transcript 48 Impactintronic_insertion
Transcript 49 Regionintron
Transcript 49 Impactintronic_insertion
Transcript 50 Regionintron
Transcript 50 Impactintronic_insertion
Transcript 51 Regionintron
Transcript 51 Impactintronic_insertion
Transcript 52 Regionintron
Transcript 52 Impactintronic_insertion
Transcript 53 Regionintron
Transcript 53 Impactintronic_insertion
Transcript 54 Regionintron
Transcript 54 Impactintronic_insertion
Transcript 55 Regionintron
Transcript 55 Impactintronic_insertion
Transcript 56 Regionintron
Transcript 56 Impactintronic_insertion
Transcript 57 Regionintron
Transcript 57 Impactintronic_insertion
Transcript 58 Regionintron
Transcript 58 Impactintronic_insertion
Transcript 59 Regionintron
Transcript 59 Impactintronic_insertion
Transcript 60 Regionintron
Transcript 60 Impactintronic_insertion
Transcript 61 Regionintron
Transcript 61 Impactintronic_insertion
Transcript 62 Regionintron
Transcript 62 Impactintronic_insertion
Transcript 63 Regionintron
Transcript 63 Impactintronic_insertion
Transcript 64 Regionintron
Transcript 64 Impactintronic_insertion
Transcript 65 Regionintron
Transcript 65 Impactintronic_insertion
Transcript 66 Regionintron
Transcript 66 Impactintronic_insertion
Transcript 67 Regionintron
Transcript 67 Impactintronic_insertion
Transcript 68 Regionintron
Transcript 68 Impactintronic_insertion
Transcript 69 Regionintron
Transcript 69 Impactintronic_insertion
Transcript 70 Region5UTR
Transcript 70 Impactnoncoding_exon_insertion
Transcript 71 Regionintron
Transcript 71 Impactintronic_insertion
Transcript 72 Regionintron
Transcript 72 Impactintronic_insertion
Transcript 73 Regionintron
Transcript 73 Impactintronic_insertion
Transcript 74 Regionintron
Transcript 74 Impactintronic_insertion
Transcript 75 Regionintron
Transcript 75 Impactintronic_insertion
Transcript 76 Regionintron
Transcript 76 Impactintronic_insertion
Transcript 77 Regionintron
Transcript 77 Impactintronic_insertion
Transcript 78 Regionintron
Transcript 78 Impactintronic_insertion
Transcript 79 Regionintron
Transcript 79 Impactintronic_insertion
Transcript 80 Regionintron
Transcript 80 Impactintronic_insertion
Transcript 81 Regionintron
Transcript 81 Impactintronic_insertion
Transcript 82 Regionintron
Transcript 82 Impactintronic_insertion
Transcript 83 Regionintron
Transcript 83 Impactintronic_insertion
Transcript 84 Regionintron
Transcript 84 Impactintronic_insertion
Transcript 85 Regionintron
Transcript 85 Impactintronic_insertion
Transcript 86 Regionintron
Transcript 86 Impactintronic_insertion
Transcript 87 Regionintron
Transcript 87 Impactintronic_insertion
Transcript 88 Regionintron
Transcript 88 Impactintronic_insertion
Transcript 89 Regionintron
Transcript 89 Impactintronic_insertion
Transcript 90 Regionintron
Transcript 90 Impactintronic_insertion
Transcript 91 Regionintron
Transcript 91 Impactintronic_insertion
Transcript 92 Regionintron
Transcript 92 Impactintronic_insertion
Transcript 93 Regionintron
Transcript 93 Impactintronic_insertion
Transcript 94 Regionintron
Transcript 94 Impactintronic_insertion
Transcript 95 Regionintron
Transcript 95 Impactintronic_insertion
Transcript 96 Regionintron
Transcript 96 Impactintronic_insertion
Transcript 97 Regionintron
Transcript 97 Impactintronic_insertion
Transcript 98 Regionintron
Transcript 98 Impactintronic_insertion
Transcript 99 Regionintron
Transcript 99 Impactintronic_insertion
Transcript 100 Regionintron
Transcript 100 Impactintronic_insertion
Transcript 101 Regionintron
Transcript 101 Impactintronic_insertion
Transcript 102 Regionintron
Transcript 102 Impactintronic_insertion
Transcript 103 Regionintron
Transcript 103 Impactintronic_insertion
Transcript 104 Regionintron
Transcript 104 Impactintronic_insertion
Transcript 105 Regionintron
Transcript 105 Impactintronic_insertion
Transcript 106 Regionintron
Transcript 106 Impactintronic_insertion
Transcript 107 Regionintron
Transcript 107 Impactintronic_insertion
SpliceAI Score
Delta ScoresAcceptor Gain: 0.070 | Acceptor Loss: 0.060 | Donor Gain: 0.010 | Donor Loss: 0.040
Delta Score Max0.070
Delta Position at Max364
Delta Score FlagLOW
GenePPM1A
AlphaGenome Analysis
Windowchr14:60212673-60343745
RNA-seq Change (±2kb)Mean: -0.00012071349192410707 | Peak: 0.681640625
ATAC Change (±2kb)Mean: 9.572916314937174e-05 | Peak: 3.578125
InterpretationRNA-seq: minimal change -0.3% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change 0.2%
Visualization
Related Links: VISDB1.0  |  UCSC  |  NCBI  |  Ensembl  |  OncoKB  |  ONGene  |  HumCFS  |  COSMIC  |  miRTarBase  |  NPInter  |  ATACdb  |  ENCODE  |  Cytoscape
UTHealth Logo

Center for Precision Health

McWilliams School of Biomedical Informatics at UTHealth Houston

7000 Fannin Street, Suite 600, Houston, TX 77030

Email: Zhongming Zhao, Ph.D

Copyright © 2025   Bioinformatics and Systems Medicine Lab.   All Rights Reserved.
Site Policies  |   Emergency Information  |   Campus Carry  |   CPH