| Basic Information ▶ | |
| VISDB ID | TVIS30014812 |
|---|---|
| Fusion Name | HIV-FCHSD2 integration |
| Validated | Yes |
| Curated Way | VISDB1.0 |
| Method | ligation mediated PCR |
| Wet Assay | Yes |
| Sample ID | PT4 |
| Sample Name | PT4 |
| Sample Type | PBMC |
| Age | 39 |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | HIV-infected disease |
| Disease Abbreviation | HID |
| Cancer | No |
| Literature ▶ | |
| PubMed ID | 24968937 |
| Journal | Science |
| Published Year | 2014 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr11 |
| Cytogenetic Band | q13.4 |
| Human Strand | - |
| Human Integration Location Type | Intronic |
| Hg19 Start | 72824164 |
| Hg19 End | 72824091 |
| Hg38 Start | 73113119 |
| Hg38 End | 73113119 |
| Junction Sequence | atttccaaagagtttatcttcaagctcactaattctttattctgcttgataaattctgctgttaagaaattat |
| Target Gene ▶ | |
| Target Gene | FCHSD2 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Immunodeficiency Virus |
| Virus Subtype Name | - |
| Virus Genome Accession | Not given |
| TaxonomyID | 11676 |
| Virus Abbreviation | HIV |
| Virus Genome | - |
| Virus Genome Length | 9719 |
| Virus Breakpoint1 | - |
| Virus Breakpoint2 | - |
| Virus Gene Name | - |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000137478.16 |
| Gene Name | FCHSD2 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000960168.1, Transcript 2: ENST00000891573.1, Transcript 3: ENST00000311172.11, Transcript 4: ENST00000891581.1, Transcript 5: ENST00000409418.9, Transcript 6: ENST00000409314.5, Transcript 7: ENST00000891575.1, Transcript 8: ENST00000891580.1, Transcript 9: ENST00000891576.1, Transcript 10: ENST00000891579.1, Transcript 11: ENST00000891578.1, Transcript 12: ENST00000891577.1, Transcript 13: ENST00000891574.1, Transcript 14: ENST00000960170.1, Transcript 15: ENST00000960169.1, Transcript 16: ENST00000891572.1, Transcript 17: ENST00000891583.1, Transcript 18: ENST00000891582.1, Transcript 19: ENST00000458644.6, Transcript 20: ENST00000409853.5, Transcript 21: ENST00000422375.1 |
| SpliceAI Score | |
| Delta Scores | Acceptor Gain: 0.000 | Acceptor Loss: 0.000 | Donor Gain: 0.000 | Donor Loss: 0.000 |
| Delta Score Max | 0.000 |
| Delta Position at Max | 1265 |
| Delta Score Flag | LOW |
| Gene | FCHSD2 |
| AlphaGenome Analysis | |
| Window | chr11:73047583-73178655 |
| RNA-seq Change (±2kb) | Mean: -0.00020163983572274446 | Peak: 0.36328125 |
| ATAC Change (±2kb) | Mean: -0.0016505010426044464 | Peak: 2.7186646461486816 |
| Interpretation | RNA-seq: minimal change -0.9% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -6.3% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D