| Basic Information ▶ | |
| VISDB ID | TVIS30015006 |
|---|---|
| Fusion Name | HIV-RSRC2 integration |
| Validated | Yes |
| Curated Way | VISDB1.0 |
| Method | ligation mediated PCR |
| Wet Assay | Yes |
| Sample ID | PT1 |
| Sample Name | PT1 |
| Sample Type | PBMC |
| Age | 47 |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | HIV-infected disease |
| Disease Abbreviation | HID |
| Cancer | No |
| Literature ▶ | |
| PubMed ID | 24968937 |
| Journal | Science |
| Published Year | 2014 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr12 |
| Cytogenetic Band | q24.31 |
| Human Strand | - |
| Human Integration Location Type | Intronic |
| Hg19 Start | 122998029 |
| Hg19 End | 122997941 |
| Hg38 Start | 122513482 |
| Hg38 End | 122513482 |
| Junction Sequence | TTTCAAGGTAGTAAATAATCTCATATTCTGAAATTAAAGAACTACATTTAAAACTTTATCTGAAAGATCACCAAGTAATCTATATATC |
| Target Gene ▶ | |
| Target Gene | RSRC2 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Immunodeficiency Virus |
| Virus Subtype Name | - |
| Virus Genome Accession | Not given |
| TaxonomyID | 11676 |
| Virus Abbreviation | HIV |
| Virus Genome | - |
| Virus Genome Length | 9719 |
| Virus Breakpoint1 | - |
| Virus Breakpoint2 | - |
| Virus Gene Name | - |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000111011.19 |
| Gene Name | RSRC2 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000331738.12, Transcript 2: ENST00000868444.1, Transcript 3: ENST00000868445.1, Transcript 4: ENST00000868447.1, Transcript 5: ENST00000868446.1, Transcript 6: ENST00000868448.1, Transcript 7: ENST00000433877.6, Transcript 8: ENST00000532695.5, Transcript 9: ENST00000527173.6, Transcript 10: ENST00000392442.6, Transcript 11: ENST00000525335.6, Transcript 12: ENST00000344591.8, Transcript 13: ENST00000528263.1, Transcript 14: ENST00000527399.3 |
| SpliceAI Score | |
| Delta Scores | Acceptor Gain: 0.000 | Acceptor Loss: 0.030 | Donor Gain: 0.050 | Donor Loss: 0.020 |
| Delta Score Max | 0.050 |
| Delta Position at Max | 285 |
| Delta Score Flag | LOW |
| Gene | RSRC2 |
| AlphaGenome Analysis | |
| Window | chr12:122447946-122579018 |
| RNA-seq Change (±2kb) | Mean: -0.002586273942142725 | Peak: 11.651611328125 |
| ATAC Change (±2kb) | Mean: -0.0002884634304791689 | Peak: 6.537841796875 |
| Interpretation | RNA-seq: minimal change -1.5% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -0.9% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D