| Basic Information ▶ | |
| VISDB ID | TVIS30015372 |
|---|---|
| Fusion Name | HIV-NFATC3 integration |
| Validated | Yes |
| Curated Way | VISDB1.0 |
| Method | ligation mediated PCR |
| Wet Assay | Yes |
| Sample ID | PT4 |
| Sample Name | PT4 |
| Sample Type | PBMC |
| Age | 39 |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | HIV-infected disease |
| Disease Abbreviation | HID |
| Cancer | No |
| Literature ▶ | |
| PubMed ID | 24968937 |
| Journal | Science |
| Published Year | 2014 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr16 |
| Cytogenetic Band | q22.1 |
| Human Strand | + |
| Human Integration Location Type | Intronic |
| Hg19 Start | 68130894 |
| Hg19 End | 68130994 |
| Hg38 Start | 68096991 |
| Hg38 End | 68096991 |
| Junction Sequence | GTGGGGACACATGTATTTGAGAAATGATAAGGGTAGAGCAGTGAAGACGACAAAGTGGGAATAGTGCTCAGATAGATTTACAGGAAAGAAATCAATAGGA |
| Target Gene ▶ | |
| Target Gene | ENSG00000261864, NFATC3 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Immunodeficiency Virus |
| Virus Subtype Name | - |
| Virus Genome Accession | Not given |
| TaxonomyID | 11676 |
| Virus Abbreviation | HIV |
| Virus Genome | - |
| Virus Genome Length | 9719 |
| Virus Breakpoint1 | - |
| Virus Breakpoint2 | - |
| Virus Gene Name | - |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000548144.1, Transcript 2: ENST00000553077.5, Transcript 3: ENST00000569766.5, Transcript 4: ENST00000563319.5, Transcript 5: ENST00000549350.5, Transcript 6: ENST00000566301.5, Transcript 7: ENST00000566893.5, Transcript 8: ENST00000575270.5, Transcript 9: ENST00000561714.5, Transcript 10: ENST00000346183.8, Transcript 11: ENST00000568466.6, Transcript 12: ENST00000539828.6, Transcript 13: ENST00000562171.1, Transcript 14: ENST00000349223.9, Transcript 15: ENST00000379165.8, Transcript 16: ENST00000329524.8, Transcript 17: ENST00000570212.5, Transcript 18: ENST00000562926.5, Transcript 19: ENST00000567152.5, Transcript 20: ENST00000563796.5, Transcript 21: ENST00000563288.5, Transcript 22: ENST00000535127.2 |
| Transcript 1 Gene Id | ENSG00000261864.1 |
| Transcript 1 Gene Name | ENSG00000261864 |
| Transcript 2 Gene Id | ENSG00000072736.19 |
| Transcript 2 Gene Name | NFATC3 |
| Transcript 3 Gene Id | ENSG00000072736.19 |
| Transcript 3 Gene Name | NFATC3 |
| Transcript 4 Gene Id | ENSG00000072736.19 |
| Transcript 4 Gene Name | NFATC3 |
| Transcript 5 Gene Id | ENSG00000072736.19 |
| Transcript 5 Gene Name | NFATC3 |
| Transcript 6 Gene Id | ENSG00000072736.19 |
| Transcript 6 Gene Name | NFATC3 |
| Transcript 7 Gene Id | ENSG00000072736.19 |
| Transcript 7 Gene Name | NFATC3 |
| Transcript 8 Gene Id | ENSG00000072736.19 |
| Transcript 8 Gene Name | NFATC3 |
| Transcript 9 Gene Id | ENSG00000072736.19 |
| Transcript 9 Gene Name | NFATC3 |
| Transcript 10 Gene Id | ENSG00000072736.19 |
| Transcript 10 Gene Name | NFATC3 |
| Transcript 11 Gene Id | ENSG00000072736.19 |
| Transcript 11 Gene Name | NFATC3 |
| Transcript 12 Gene Id | ENSG00000072736.19 |
| Transcript 12 Gene Name | NFATC3 |
| Transcript 13 Gene Id | ENSG00000072736.19 |
| Transcript 13 Gene Name | NFATC3 |
| Transcript 14 Gene Id | ENSG00000072736.19 |
| Transcript 14 Gene Name | NFATC3 |
| Transcript 15 Gene Id | ENSG00000072736.19 |
| Transcript 15 Gene Name | NFATC3 |
| Transcript 16 Gene Id | ENSG00000072736.19 |
| Transcript 16 Gene Name | NFATC3 |
| Transcript 17 Gene Id | ENSG00000072736.19 |
| Transcript 17 Gene Name | NFATC3 |
| Transcript 18 Gene Id | ENSG00000072736.19 |
| Transcript 18 Gene Name | NFATC3 |
| Transcript 19 Gene Id | ENSG00000072736.19 |
| Transcript 19 Gene Name | NFATC3 |
| Transcript 20 Gene Id | ENSG00000072736.19 |
| Transcript 20 Gene Name | NFATC3 |
| Transcript 21 Gene Id | ENSG00000072736.19 |
| Transcript 21 Gene Name | NFATC3 |
| Transcript 22 Gene Id | ENSG00000072736.19 |
| Transcript 22 Gene Name | NFATC3 |
| SpliceAI Score | |
| Delta Scores | Acceptor Gain: 0.010 | Acceptor Loss: 0.000 | Donor Gain: 0.020 | Donor Loss: 0.000 |
| Delta Score Max | 0.020 |
| Delta Position at Max | -535 |
| Delta Score Flag | LOW |
| Gene | NFATC3 |
| AlphaGenome Analysis | |
| Window | chr16:68031455-68162527 |
| RNA-seq Change (±2kb) | Mean: -0.0003995953011326492 | Peak: 0.3046875 |
| ATAC Change (±2kb) | Mean: -0.00024389084137510508 | Peak: 7.0859375 |
| Interpretation | RNA-seq: minimal change -3.2% | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -0.9% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D