| Basic Information ▶ | |
| VISDB ID | TVIS30015952 |
|---|---|
| Fusion Name | HIV-PAXBP1 integration |
| Validated | Yes |
| Curated Way | VISDB1.0 |
| Method | ligation mediated PCR |
| Wet Assay | Yes |
| Sample ID | PT1 |
| Sample Name | PT1 |
| Sample Type | PBMC |
| Age | 47 |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | HIV-infected disease |
| Disease Abbreviation | HID |
| Cancer | No |
| Literature ▶ | |
| PubMed ID | 24968937 |
| Journal | Science |
| Published Year | 2014 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr21 |
| Cytogenetic Band | q22.11 |
| Human Strand | - |
| Human Integration Location Type | Intronic |
| Hg19 Start | 34123366 |
| Hg19 End | 34123124 |
| Hg38 Start | 32751055 |
| Hg38 End | 32751055 |
| Junction Sequence | TCTAATGCAGAGACCATGAAGATTCAAATCATTTCATGGTAAAAACCATACCCAAGTAGAAACTAAACTGATGATGAGTCTTATTTCCAAATAAATGTCTAACCTTTTTCCAGATTGAAATTAGTAATATCTGTAGAAGTTTCTTCATCATCACTGGAAAGGCCTTCAAGGTGATCTGCCATCTTACCGGTTTGTTCTCTGGCTTGTCTACGACGAGTCCTAAATAATAAACATCAAGTTCC |
| Target Gene ▶ | |
| Target Gene | PAXBP1 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Human Immunodeficiency Virus |
| Virus Subtype Name | - |
| Virus Genome Accession | Not given |
| TaxonomyID | 11676 |
| Virus Abbreviation | HIV |
| Virus Genome | - |
| Virus Genome Length | 9719 |
| Virus Breakpoint1 | - |
| Virus Breakpoint2 | - |
| Virus Gene Name | - |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000159086.16 |
| Gene Name | PAXBP1 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000331923.9, Transcript 2: ENST00000466846.5, Transcript 3: ENST00000962012.1, Transcript 4: ENST00000962014.1, Transcript 5: ENST00000962013.1, Transcript 6: ENST00000443785.5, Transcript 7: ENST00000497873.1, Transcript 8: ENST00000290178.4, Transcript 9: ENST00000421049.1 |
| SpliceAI Score | |
| Delta Scores | Acceptor Gain: 1.000 | Acceptor Loss: 0.090 | Donor Gain: 1.000 | Donor Loss: 0.030 |
| Delta Score Max | 1.000 |
| Delta Position at Max | 0 |
| Delta Score Flag | HIGH_PRECISION |
| Gene | PAXBP1 |
| AlphaGenome Analysis | |
| Chromosome | chr21 |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D