| Basic Information ▶ | |
| VISDB ID | TVIS42001649 |
|---|---|
| Fusion Name | EBV-PPME1 integration |
| Validated | No |
| Curated Way | Curated |
| Method | EBV capture sequencing, followed by Viral Integration Pathway Analysis (VIPA) pipeline |
| Wet Assay | No |
| Sample ID | SRR8574864.7 |
| Sample Name | SRP185895 |
| Sample Type | Tumor |
| Age | - |
| Gender | - |
| Disease Information ▶ | |
| Disease Name | Multiple |
| Disease Abbreviation | - |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 35968887 |
| Journal | Clinical and Translational Medicine |
| Published Year | 2022 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh38/hg38 |
| Human Genome RefSeq Accession | GCF_000001405.40 |
| Human Chromosome | chr11 |
| Cytogenetic Band | q13.4 |
| Human Strand | + |
| Human Integration Location Type | intronic |
| Hg19 Start | - |
| Hg19 End | - |
| Hg38 Start | 74174189 |
| Hg38 End | 74174189 |
| Junction Sequence | tACAGGGTGGGAGAAGGGAACTGGACATCATTAGATGGGGGGACTGCATGTTCTCACTCATGTATTAATAAATGAGGGAACTGAGACTCAGATATTCCTAg |
| Target Gene ▶ | |
| Target Gene | PPME1 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | Epstein-Barr Virus |
| Virus Subtype Name | - |
| Virus Genome Accession | NC_007605 |
| TaxonomyID | 10376 |
| Virus Abbreviation | EBV |
| Virus Genome | Human gammaherpesvirus 4, complete genome |
| Virus Genome Length | 171823 bp |
| Virus Breakpoint1 | 89286 |
| Virus Breakpoint2 | - |
| Virus Gene Name | EBNA-1,EBNA-3B/EBNA-3C,EBNA-1,BZLF2 |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000214517.11 |
| Gene Name | PPME1 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000856423.1, Transcript 2: ENST00000921187.1, Transcript 3: ENST00000542710.3, Transcript 4: ENST00000856424.1, Transcript 5: ENST00000970219.1, Transcript 6: ENST00000970220.1, Transcript 7: ENST00000328257.13, Transcript 8: ENST00000921188.1, Transcript 9: ENST00000856425.1, Transcript 10: ENST00000856426.1, Transcript 11: ENST00000398427.6, Transcript 12: ENST00000970221.1, Transcript 13: ENST00000856427.1, Transcript 14: ENST00000544401.2, Transcript 15: ENST00000970222.1, Transcript 16: ENST00000856428.1 |
| SpliceAI Score | |
| Delta Scores | Acceptor Gain: 0.000 | Acceptor Loss: 0.000 | Donor Gain: 0.000 | Donor Loss: 0.000 |
| Delta Score Max | 0.000 |
| Delta Position at Max | 601 |
| Delta Score Flag | LOW |
| Gene | PPME1 |
| AlphaGenome Analysis | |
| Chromosome | chr11 |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D