| Basic Information ▶ | |
| VISDB ID | TVIS46000264 |
|---|---|
| Fusion Name | BKPyv-ENSG00000286481 integration |
| Validated | No |
| Curated Way | Curated |
| Method | Virome capture next-generation sequencing |
| Wet Assay | Yes |
| Sample ID | - |
| Sample Name | Case17_Urine |
| Sample Type | Tumor |
| Age | - |
| Gender | Female |
| Disease Information ▶ | |
| Disease Name | Urothelial carcinoma |
| Disease Abbreviation | UC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 37507072 |
| Journal | American Journal of Transplantation |
| Published Year | 2023 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr2 |
| Cytogenetic Band | q14.3 |
| Human Strand | - |
| Human Integration Location Type | intronic |
| Hg19 Start | 123127364 |
| Hg19 End | 123127364 |
| Hg38 Start | 122369788 |
| Hg38 End | 122369788 |
| Junction Sequence | CAAGTACCTCAGAGGCTATAGCTGCTATAGGCCTAACTCCTCAAACATATGCTGTAATTGCTGGTGCTCCAGGGGCTATTGCTGGGTTTGCTGCTTTAATTCAAACTGTTACTGGTGTTAGTTCTTTGGCTCAAGTAGGGTAACTATTGAACCTGGAGGTTGTTTCTGAATATCTAGAGTCTTCATGGTCTTCAATGTTCAGCCATCATTTTATGCTTTAAAAAAATTTCTTGGCTGGAAAATCTTTGAG |
| Target Gene ▶ | |
| Target Gene | ENSG00000286481 |
| Nearby Gene | - |
| Distance | - |
| Virus Information ▶ | |
| Virus Name | BK polyomavirus |
| Virus Subtype Name | Genotype I, IV |
| Virus Genome Accession | AB217919.1 |
| TaxonomyID | 1417981 |
| Virus Abbreviation | BKPyV |
| Virus Genome | BK polyomavirus DNA, complete genome, isolate: TW-3a |
| Virus Genome Length | 5146 bp |
| Virus Breakpoint1 | 799 |
| Virus Breakpoint2 | - |
| Virus Gene Name | AB217919.1_VP2 |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000286481.3 |
| Gene Name | ENSG00000286481 |
| Region | intron |
| Impact | intronic_insertion |
| Transcript | Transcript 1: ENST00000657880.2, Transcript 2: ENST00000819524.1, Transcript 3: ENST00000819525.1, Transcript 4: ENST00000819526.1 |
| AlphaGenome Analysis | |
| Window | chr2:122304252-122435324 |
| RNA-seq Change (±2kb) | Mean: -1.3764142750005703e-05 | Peak: 0.008544921875 |
| ATAC Change (±2kb) | Mean: -0.0008567121112719178 | Peak: 1.21875 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change -3.3% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D