| Basic Information ▶ | |
| VISDB ID | TVIS46000918 |
|---|---|
| Fusion Name | BKPyV-chr10:80718617 integration |
| Validated | No |
| Curated Way | Curated |
| Method | Virome capture next-generation sequencing |
| Wet Assay | Yes |
| Sample ID | - |
| Sample Name | Case16_blood |
| Sample Type | Tumor |
| Age | - |
| Gender | Male |
| Disease Information ▶ | |
| Disease Name | Urothelial carcinoma |
| Disease Abbreviation | UC |
| Cancer | Yes |
| Literature ▶ | |
| PubMed ID | 37507072 |
| Journal | American Journal of Transplantation |
| Published Year | 2023 |
| Human Genome ▶ | |
| Human Genome Version Description | GRCh37/hg19 |
| Human Genome RefSeq Accession | GCF_000001405.13 |
| Human Chromosome | chr10 |
| Cytogenetic Band | q23.1 |
| Human Strand | + |
| Human Integration Location Type | intergenic |
| Hg19 Start | 82478373 |
| Hg19 End | 82478373 |
| Hg38 Start | 80718617 |
| Hg38 End | 80718617 |
| Junction Sequence | CTGTGTCATTTAGTCTTGACAGCATCATGTGAGGCAGGACTTTTTTTTTTCTAAAAAAGAAGGGGCTCTTGCCCCATTTTTCATTAAAGGAACTCCACCAGGACTCCCACTCTTCTGTTCCATAGGTTGGCACCTAGAAAAAAA |
| Target Gene ▶ | |
| Target Gene | - |
| Nearby Gene | RPS7P9 |
| Distance | 1549 |
| Virus Information ▶ | |
| Virus Name | BK polyomavirus |
| Virus Subtype Name | Genotype I, IV |
| Virus Genome Accession | AB217921.1 |
| TaxonomyID | 1417981 |
| Virus Abbreviation | BKPyV |
| Virus Genome | BK polyomavirus DNA, complete genome, isolate: THK-9a |
| Virus Genome Length | 5142 bp |
| Virus Breakpoint1 | 4385 |
| Virus Breakpoint2 | - |
| Virus Gene Name | AB217921.1_large T |
| Virus Region Type | - |
| Integrated Virus Sequence | - |
| ViMIC ID | - |
| Predicted VIS Effect ▶ | |
| Gene Id | ENSG00000233353.1 |
| Gene Name | RPS7P9 |
| Region | promoter |
| Impact | promoter_insertion |
| Transcript | Transcript 1: ENST00000414704.1 |
| AlphaGenome Analysis | |
| Window | chr10:80653081-80784153 |
| RNA-seq Change (±2kb) | Mean: 3.1369923817692325e-05 | Peak: 0.005126953125 |
| ATAC Change (±2kb) | Mean: 0.0001655687519814819 | Peak: 1.698486328125 |
| Interpretation | RNA-seq: no signal in region (REF≈0, ALT≈0) | Splice sites: no signal in region (REF≈0, ALT≈0) | ATAC: minimal change 0.6% |
| Visualization | |
Center for Precision Health
McWilliams School of Biomedical Informatics at UTHealth Houston
7000 Fannin Street, Suite 600, Houston, TX 77030
Email: Zhongming Zhao, Ph.D