| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10007669 | HBV | ENSG00000118520.16 | protein_coding | ARG1 | No | No | 383 | P05089 |
| TVIS10062719 | HBV | ENSG00000118520.16 | protein_coding | ARG1 | No | No | 383 | P05089 |
| TVIS30077929 | HIV | ENSG00000118520.16 | protein_coding | ARG1 | No | No | 383 | P05089 |
| TVIS30020841 | HIV | ENSG00000118520.16 | protein_coding | ARG1 | No | No | 383 | P05089 |
| TVIS20061167 | HPV | ENSG00000118520.16 | protein_coding | ARG1 | No | No | 383 | P05089 |
| TVIS44030148 | HTLV-1 | ENSG00000118520.16 | protein_coding | ARG1 | No | No | 383 | P05089 |
| TVIS44003144 | HTLV-1 | ENSG00000118520.16 | protein_coding | ARG1 | No | No | 383 | P05089 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ARG1 |
|---|---|
| DrugBank ID | DB00129 |
| Drug Name | Ornithine |
| Target ID | BE0000286 |
| UniProt ID | P05089 |
| Regulation Type | |
| PubMed IDs | 11971019; 12135320; 12446178; 12589193; 12679340 |
| Citations | Gobert AP, Cheng Y, Wang JY, Boucher JL, Iyer RK, Cederbaum SD, Casero RA Jr, Newton JC, Wilson KT: Helicobacter pylori induces macrophage apoptosis by activation of arginase II. J Immunol. 2002 May 1;168(9):4692-700.@@Iwata S, Tsujino T, Ikeda Y, Ishida T, Ueyama T, Gotoh T, Mori M, Yokoyama M: Decreased expression of arginase II in the kidneys of Dahl salt-sensitive rats. Hypertens Res. 2002 May;25(3):411-8.@@Stickings P, Mistry SK, Boucher JL, Morris SM, Cunningham JM: Arginase expression and modulation of IL-1beta-induced nitric oxide generation in rat and human islets of Langerhans. Nitric Oxide. 2002 Dec;7(4):289-96.@@Bansal V, Ochoa JB: Arginine availability, arginase, and the immune response. Curr Opin Clin Nutr Metab Care. 2003 Mar;6(2):223-8.@@El Alami M, Dubois E, Oudjama Y, Tricot C, Wouters J, Stalon V, Messenguy F: Yeast epiarginase regulation, an enzyme-enzyme activity control: identification of residues of ornithine carbamoyltransferase and arginase responsible for enzyme catalytic and regulatory activities. J Biol Chem. 2003 Jun 13;278(24):21550-8. Epub 2003 Apr 4. |
| Groups | Approved; Nutraceutical |
| Direct Classification | L-alpha-amino acids |
| SMILES | NCCC[C@H](N)C(O)=O |
| Pathways | Citrullinemia Type I; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Argininemia; Hyperornithinemia with Gyrate Atrophy (HOGA); Spermidine and Spermine Biosynthesis; Hyperprolinemia Type II; Argininosuccinic Aciduria; L-Arginine:Glycine Amidinotransferase Deficiency; Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Prolidase Deficiency (PD); Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Carbamoyl Phosphate Synthetase Deficiency; Ornithine Aminotransferase Deficiency (OAT Deficiency); Hyperprolinemia Type I; Arginine and Proline Metabolism; Ornithine Transcarbamylase Deficiency (OTC Deficiency); Prolinemia Type II; Urea Cycle |
| PharmGKB | PA164783814 |
| ChEMBL | CHEMBL446143 |
