| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30013706 | HIV | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
| TVIS30079750 | HIV | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
| TVIS20063902 | HPV | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
| TVIS44005723 | HTLV-1 | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
| TVIS44017072 | HTLV-1 | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
| TVIS44017073 | HTLV-1 | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
| TVIS44040312 | HTLV-1 | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
| TVIS44040311 | HTLV-1 | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
| TVIS44040078 | HTLV-1 | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
| TVIS44040186 | HTLV-1 | ENSG00000086062.14 | protein_coding | B4GALT1 | No | No | 2683 | P15291 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | B4GALT1 |
|---|---|
| DrugBank ID | DB00141 |
| Drug Name | N-Acetylglucosamine |
| Target ID | BE0000259 |
| UniProt ID | P15291 |
| Regulation Type | |
| PubMed IDs | 15736931; 16157350; 17370997; 17203585; 15449940 |
| Citations | Ramakrishnan B, Boeggeman E, Qasba PK: Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase I. Biochemistry. 2005 Mar 8;44(9):3202-10.@@Ramasamy V, Ramakrishnan B, Boeggeman E, Ratner DM, Seeberger PH, Qasba PK: Oligosaccharide preferences of beta1,4-galactosyltransferase-I: crystal structures of Met340His mutant of human beta1,4-galactosyltransferase-I with a pentasaccharide and trisaccharides of the N-glycan moiety. J Mol Biol. 2005 Oct 14;353(1):53-67.@@Boeggeman E, Ramakrishnan B, Kilgore C, Khidekel N, Hsieh-Wilson LC, Simpson JT, Qasba PK: Direct identification of nonreducing GlcNAc residues on N-glycans of glycoproteins using a novel chemoenzymatic method. Bioconjug Chem. 2007 May-Jun;18(3):806-14. Epub 2007 Mar 20.@@Hidalgo A, Burgos V, Viola H, Medina J, Argibay P: Differential expression of glycans in the hippocampus of rats trained on an inhibitory learning paradigm. Neuropathology. 2006 Dec;26(6):501-7.@@Ramakrishnan B, Boeggeman E, Qasba PK: Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose. Biochemistry. 2004 Oct 5;43(39):12513-22. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Hexoses |
| SMILES | [H]C(=O)[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@H](O)CO |
| Pathways | G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease; Sialuria or French Type Sialuria; Tay-Sachs Disease; Salla Disease/Infantile Sialic Acid Storage Disease; Amino Sugar Metabolism |
| PharmGKB | PA164752287 |
| ChEMBL | CHEMBL4303483 |
