| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30013884 | HIV | ENSG00000126581.13 | protein_coding | BECN1 | No | No | 8678 | A0A024R1X5 E7EV84 Q14457 |
| TVIS30043979 | HIV | ENSG00000126581.13 | protein_coding | BECN1 | No | No | 8678 | A0A024R1X5 E7EV84 Q14457 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | BECN1 |
|---|---|
| DrugBank ID | DB00783 |
| Drug Name | Estradiol |
| Target ID | BE0009015 |
| UniProt ID | Q14457 |
| Regulation Type | binder |
| PubMed IDs | 21034808; 23274738 |
| Citations | Van Dorst B, Mehta J, Rouah-Martin E, De Coen W, Blust R, Robbens J: The identification of cellular targets of 17beta estradiol using a lytic (T7) cDNA phage display approach. Toxicol In Vitro. 2011 Feb;25(1):388-93. doi: 10.1016/j.tiv.2010.10.012. Epub 2010 Oct 27.@@Moreno AJ, Moreira PI, Custodio JB, Santos MS: Mechanism of inhibition of mitochondrial ATP synthase by 17beta-estradiol. J Bioenerg Biomembr. 2013 Jun;45(3):261-70. doi: 10.1007/s10863-012-9497-1. Epub 2012 Dec 29. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Estrogens and derivatives |
| SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(O)C=C3 |
| Pathways | Estrone Metabolism; Aromatase Deficiency; Androgen and Estrogen Metabolism; 17-beta Hydroxysteroid Dehydrogenase III Deficiency |
| PharmGKB | PA449503 |
| ChEMBL | CHEMBL135 |
