| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20033012 | HPV | ENSG00000157388.20 | protein_coding | CACNA1D | Yes | No | 776 | A0A1B0GUN6 Q01668 |
| TVIS20065014 | HPV | ENSG00000157388.20 | protein_coding | CACNA1D | Yes | No | 776 | A0A1B0GUN6 Q01668 |
| TVIS44025094 | HTLV-1 | ENSG00000157388.20 | protein_coding | CACNA1D | Yes | No | 776 | A0A1B0GUN6 Q01668 |
| TVIS44028682 | HTLV-1 | ENSG00000157388.20 | protein_coding | CACNA1D | Yes | No | 776 | A0A1B0GUN6 Q01668 |
| TVIS44004850 | HTLV-1 | ENSG00000157388.20 | protein_coding | CACNA1D | Yes | No | 776 | A0A1B0GUN6 Q01668 |
| TVIS44048791 | HTLV-1 | ENSG00000157388.20 | protein_coding | CACNA1D | Yes | No | 776 | A0A1B0GUN6 Q01668 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1D |
|---|---|
| DrugBank ID | DB00270 |
| Drug Name | Isradipine |
| Target ID | BE0002359 |
| UniProt ID | Q01668 |
| Regulation Type | inhibitor |
| PubMed IDs | 11285265; 19029287 |
| Citations | Koschak A, Reimer D, Huber I, Grabner M, Glossmann H, Engel J, Striessnig J: alpha 1D (Cav1.3) subunits can form l-type Ca2+ channels activating at negative voltages. J Biol Chem. 2001 Jun 22;276(25):22100-6. Epub 2001 Apr 2.@@Sinnegger-Brauns MJ, Huber IG, Koschak A, Wild C, Obermair GJ, Einzinger U, Hoda JC, Sartori SB, Striessnig J: Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms. Mol Pharmacol. 2009 Feb;75(2):407-14. doi: 10.1124/mol.108.049981. Epub 2008 Nov 24. |
| Groups | Approved; Investigational |
| Direct Classification | Benzoxadiazoles |
| SMILES | COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC2=NON=C12)C(=O)OC(C)C |
| Pathways | Isradipine Action Pathway |
| PharmGKB | PA450131 |
| ChEMBL | CHEMBL1648 |
