| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10019030 | HBV | ENSG00000121691.7 | protein_coding | CAT | No | No | 847 | P04040 |
| TVIS30010175 | HIV | ENSG00000121691.7 | protein_coding | CAT | No | No | 847 | P04040 |
| TVIS30029291 | HIV | ENSG00000121691.7 | protein_coding | CAT | No | No | 847 | P04040 |
| TVIS30029292 | HIV | ENSG00000121691.7 | protein_coding | CAT | No | No | 847 | P04040 |
| TVIS30029293 | HIV | ENSG00000121691.7 | protein_coding | CAT | No | No | 847 | P04040 |
| TVIS44011694 | HTLV-1 | ENSG00000121691.7 | protein_coding | CAT | No | No | 847 | P04040 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CAT |
|---|---|
| DrugBank ID | DB01213 |
| Drug Name | Fomepizole |
| Target ID | BE0001207 |
| UniProt ID | P04040 |
| Regulation Type | inhibitor |
| PubMed IDs | 240743; 3416882; 8423764 |
| Citations | Thurman RG, McKenna WR, Brentzel HJ Jr, Hesse S: Significant pathways of hepatic ethanol metabolism. Fed Proc. 1975 Oct;34(11):2075-81.@@Handler JA, Thurman RG: Catalase-dependent ethanol oxidation in perfused rat liver. Requirement for fatty-acid-stimulated H2O2 production by peroxisomes. Eur J Biochem. 1988 Sep 15;176(2):477-84.@@Bradford BU, Forman DT, Thurman RG: 4-Methylpyrazole inhibits fatty acyl coenzyme synthetase and diminishes catalase-dependent alcohol metabolism: has the contribution of alcohol dehydrogenase to alcohol metabolism been previously overestimated? Mol Pharmacol. 1993 Jan;43(1):115-9. |
| Groups | Approved; Vet_approved |
| Direct Classification | Pyrazoles |
| SMILES | CC1=CNN=C1 |
| Pathways | |
| PharmGKB | PA449697 |
| ChEMBL | CHEMBL1308 |
