| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10048330 | HBV | ENSG00000005469.12 | protein_coding | CROT | No | No | 54677 | Q9UKG9 |
| TVIS30003997 | HIV | ENSG00000005469.12 | protein_coding | CROT | No | No | 54677 | Q9UKG9 |
| TVIS30014392 | HIV | ENSG00000005469.12 | protein_coding | CROT | No | No | 54677 | Q9UKG9 |
| TVIS30003998 | HIV | ENSG00000005469.12 | protein_coding | CROT | No | No | 54677 | Q9UKG9 |
| TVIS30067435 | HIV | ENSG00000005469.12 | protein_coding | CROT | No | No | 54677 | Q9UKG9 |
| TVIS20026315 | HPV | ENSG00000005469.12 | protein_coding | CROT | No | No | 54677 | Q9UKG9 |
| TVIS20062169 | HPV | ENSG00000005469.12 | protein_coding | CROT | No | No | 54677 | Q9UKG9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CROT |
|---|---|
| DrugBank ID | DB00583 |
| Drug Name | Levocarnitine |
| Target ID | BE0000373 |
| UniProt ID | Q9UKG9 |
| Regulation Type | |
| PubMed IDs | 15155769; 16681386 |
| Citations | Cordente AG, Lopez-Vinas E, Vazquez MI, Swiegers JH, Pretorius IS, Gomez-Puertas P, Hegardt FG, Asins G, Serra D: Redesign of carnitine acetyltransferase specificity by protein engineering. J Biol Chem. 2004 Aug 6;279(32):33899-908. Epub 2004 May 21.@@Cordente AG, Lopez-Vinas E, Vazquez MI, Gomez-Puertas P, Asins G, Serra D, Hegardt FG: Mutagenesis of specific amino acids converts carnitine acetyltransferase into carnitine palmitoyltransferase. Biochemistry. 2006 May 16;45(19):6133-41. |
| Groups | Approved; Investigational |
| Direct Classification | Carnitines |
| SMILES | C[N+](C)(C)C[C@H](O)CC([O-])=O |
| Pathways | Carnitine Palmitoyl Transferase Deficiency II; Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD); Ethylmalonic Encephalopathy; Glutaric Aciduria Type I; Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency); Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD); Carnitine Palmitoyl Transferase Deficiency I; Oxidation of Branched-Chain Fatty Acids; Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids; Fatty Acid Metabolism; Beta Oxidation of Very Long Chain Fatty Acids; Carnitine-Acylcarnitine Translocase Deficiency; Carnitine Synthesis; Trifunctional Protein Deficiency; Adrenoleukodystrophy, X-Linked; Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD) |
| PharmGKB | PA450154 |
| ChEMBL | CHEMBL1149 |
