| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30088330 | HIV | ENSG00000103653.17 | protein_coding | CSK | No | No | 1445 | B2R6Q4 P41240 |
| TVIS30075534 | HIV | ENSG00000103653.17 | protein_coding | CSK | No | No | 1445 | B2R6Q4 P41240 |
| TVIS30038917 | HIV | ENSG00000103653.17 | protein_coding | CSK | No | No | 1445 | B2R6Q4 P41240 |
| TVIS20052448 | HPV | ENSG00000103653.17 | protein_coding | CSK | No | No | 1445 | B2R6Q4 P41240 |
| TVIS20044367 | HPV | ENSG00000103653.17 | protein_coding | CSK | No | No | 1445 | B2R6Q4 P41240 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CSK |
|---|---|
| DrugBank ID | DB01254 |
| Drug Name | Dasatinib |
| Target ID | BE0001356 |
| UniProt ID | P41240 |
| Regulation Type | inhibitor |
| PubMed IDs | 18180381; 22928736 |
| Citations | Kneidinger M, Schmidt U, Rix U, Gleixner KV, Vales A, Baumgartner C, Lupinek C, Weghofer M, Bennett KL, Herrmann H, Schebesta A, Thomas WR, Vrtala S, Valenta R, Lee FY, Ellmeier W, Superti-Furga G, Valent P: The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils. Blood. 2008 Mar 15;111(6):3097-107. doi: 10.1182/blood-2007-08-104372. Epub 2008 Jan 7.@@Kwarcinski FE, Fox CC, Steffey ME, Soellner MB: Irreversible inhibitors of c-Src kinase that target a nonconserved cysteine. ACS Chem Biol. 2012 Nov 16;7(11):1910-7. doi: 10.1021/cb300337u. Epub 2012 Sep 5. |
| Groups | Approved; Investigational |
| Direct Classification | Aromatic anilides |
| SMILES | CC1=NC(NC2=NC=C(S2)C(=O)NC2=C(C)C=CC=C2Cl)=CC(=N1)N1CCN(CCO)CC1 |
| Pathways | Dasatinib Inhibition of BCR-ABL |
| PharmGKB | PA162372878 |
| ChEMBL | CHEMBL1421 |
