| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30010584 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30015669 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30007413 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30002958 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30012523 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30007414 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30002959 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30007415 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30007416 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30002960 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | DNMT1 |
|---|---|
| DrugBank ID | DB00721 |
| Drug Name | Procaine |
| Target ID | BE0000892 |
| UniProt ID | P26358 |
| Regulation Type | inhibitor |
| PubMed IDs | 12941824; 28926119 |
| Citations | Villar-Garea A, Fraga MF, Espada J, Esteller M: Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res. 2003 Aug 15;63(16):4984-9.@@Li YC, Wang Y, Li DD, Zhang Y, Zhao TC, Li CF: Procaine is a specific DNA methylation inhibitor with anti-tumor effect for human gastric cancer. J Cell Biochem. 2018 Feb;119(2):2440-2449. doi: 10.1002/jcb.26407. Epub 2017 Oct 27. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Benzoic acid esters |
| SMILES | CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 |
| Pathways | Procaine Action Pathway |
| PharmGKB | PA451110 |
| ChEMBL | CHEMBL569 |
