| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10051767 | HBV | ENSG00000142627.13 | protein_coding | EPHA2 | No | No | 1969 | P29317 |
| TVIS20069265 | HPV | ENSG00000142627.13 | protein_coding | EPHA2 | No | No | 1969 | P29317 |
| TVIS20064798 | HPV | ENSG00000142627.13 | protein_coding | EPHA2 | No | No | 1969 | P29317 |
| TVIS20016949 | HPV | ENSG00000142627.13 | protein_coding | EPHA2 | No | No | 1969 | P29317 |
| TVIS20019559 | HPV | ENSG00000142627.13 | protein_coding | EPHA2 | No | No | 1969 | P29317 |
| TVIS44024403 | HTLV-1 | ENSG00000142627.13 | protein_coding | EPHA2 | No | No | 1969 | P29317 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | EPHA2 |
|---|---|
| DrugBank ID | DB01254 |
| Drug Name | Dasatinib |
| Target ID | BE0000841 |
| UniProt ID | P29317 |
| Regulation Type | antagonist |
| PubMed IDs | 20072833; 18420784 |
| Citations | Lindauer M, Hochhaus A: Dasatinib. Recent Results Cancer Res. 2010;184:83-102. doi: 10.1007/978-3-642-01222-8_7.@@Christopher LJ, Cui D, Wu C, Luo R, Manning JA, Bonacorsi SJ, Lago M, Allentoff A, Lee FY, McCann B, Galbraith S, Reitberg DP, He K, Barros A Jr, Blackwood-Chirchir A, Humphreys WG, Iyer RA: Metabolism and disposition of dasatinib after oral administration to humans. Drug Metab Dispos. 2008 Jul;36(7):1357-64. doi: 10.1124/dmd.107.018267. Epub 2008 Apr 17. |
| Groups | Approved; Investigational |
| Direct Classification | Aromatic anilides |
| SMILES | CC1=NC(NC2=NC=C(S2)C(=O)NC2=C(C)C=CC=C2Cl)=CC(=N1)N1CCN(CCO)CC1 |
| Pathways | Dasatinib Inhibition of BCR-ABL |
| PharmGKB | PA162372878 |
| ChEMBL | CHEMBL1421 |
