Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10015153HBVENSG00000171503.13protein_codingETFDHNoNo2110B4DEQ0
Q16134
TVIS10029828HBVENSG00000171503.13protein_codingETFDHNoNo2110B4DEQ0
Q16134
TVIS30061409HIVENSG00000171503.13protein_codingETFDHNoNo2110B4DEQ0
Q16134
TVIS30017725HIVENSG00000171503.13protein_codingETFDHNoNo2110B4DEQ0
Q16134
TVIS20020599HPVENSG00000171503.13protein_codingETFDHNoNo2110B4DEQ0
Q16134
TCGA Plot Options
Drug Information
GeneETFDH
DrugBank IDDB00331
Drug NameMetformin
Target IDBE0003887
UniProt IDQ16134
Regulation Typeinhibitor
PubMed IDs22117616; 30619086
CitationsViollet B, Guigas B, Sanz Garcia N, Leclerc J, Foretz M, Andreelli F: Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond). 2012 Mar;122(6):253-70. doi: 10.1042/CS20110386.@@Fontaine E: Metformin-Induced Mitochondrial Complex I Inhibition: Facts, Uncertainties, and Consequences. Front Endocrinol (Lausanne). 2018 Dec 17;9:753. doi: 10.3389/fendo.2018.00753. eCollection 2018.
GroupsApproved
Direct ClassificationBiguanides
SMILESCN(C)C(=N)NC(N)=N
Pathways
PharmGKBPA450395
ChEMBLCHEMBL1431