| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10006894 | HBV | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
| TVIS10006879 | HBV | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
| TVIS10006888 | HBV | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
| TVIS10016544 | HBV | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
| TVIS10027378 | HBV | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
| TVIS10059178 | HBV | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
| TVIS20033309 | HPV | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
| TVIS20034947 | HPV | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
| TVIS44030758 | HTLV-1 | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
| TVIS44027190 | HTLV-1 | ENSG00000171766.17 | protein_coding | GATM | No | No | 2628 | P50440 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GATM |
|---|---|
| DrugBank ID | DB00129 |
| Drug Name | Ornithine |
| Target ID | BE0000347 |
| UniProt ID | P50440 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 7173402; 11691635; 5335895 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Thomasset N, Quash GA, Dore JF: The differential contribution of arginase and transamidinase to ornithine biosynthesis in two achromic human melanoma cell lines. FEBS Lett. 1982 Nov 1;148(1):63-6.@@Natesan S, Reddy SR: Compensatory changes in enzymes of arginine metabolism during renal hypertrophy in mice. Comp Biochem Physiol B Biochem Mol Biol. 2001 Dec;130(4):585-95.@@Mitruka BM, Costilow RN: Arginine and ornithine catabolism by Clostridium botulinum. J Bacteriol. 1967 Jan;93(1):295-301. |
| Groups | Approved; Nutraceutical |
| Direct Classification | L-alpha-amino acids |
| SMILES | NCCC[C@H](N)C(O)=O |
| Pathways | Citrullinemia Type I; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Argininemia; Hyperornithinemia with Gyrate Atrophy (HOGA); Spermidine and Spermine Biosynthesis; Hyperprolinemia Type II; Argininosuccinic Aciduria; L-Arginine:Glycine Amidinotransferase Deficiency; Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Prolidase Deficiency (PD); Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Carbamoyl Phosphate Synthetase Deficiency; Ornithine Aminotransferase Deficiency (OAT Deficiency); Hyperprolinemia Type I; Arginine and Proline Metabolism; Ornithine Transcarbamylase Deficiency (OTC Deficiency); Prolinemia Type II; Urea Cycle |
| PharmGKB | PA164783814 |
| ChEMBL | CHEMBL446143 |
