| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42001167 | EBV | ENSG00000234745.14 | protein_coding | HLA-B | No | Yes | 3106 | E5FQ95 P01889 |
| TVIS10017600 | HBV | ENSG00000234745.14 | protein_coding | HLA-B | No | Yes | 3106 | E5FQ95 P01889 |
| TVIS10018971 | HBV | ENSG00000234745.14 | protein_coding | HLA-B | No | Yes | 3106 | E5FQ95 P01889 |
| TVIS30016392 | HIV | ENSG00000234745.14 | protein_coding | HLA-B | No | Yes | 3106 | E5FQ95 P01889 |
| TVIS30003827 | HIV | ENSG00000234745.14 | protein_coding | HLA-B | No | Yes | 3106 | E5FQ95 P01889 |
| TVIS30017639 | HIV | ENSG00000234745.14 | protein_coding | HLA-B | No | Yes | 3106 | E5FQ95 P01889 |
| TVIS20060756 | HPV | ENSG00000234745.14 | protein_coding | HLA-B | No | Yes | 3106 | E5FQ95 P01889 |
| TVIS44034138 | HTLV-1 | ENSG00000234745.14 | protein_coding | HLA-B | No | Yes | 3106 | E5FQ95 P01889 |
| TVIS44034139 | HTLV-1 | ENSG00000234745.14 | protein_coding | HLA-B | No | Yes | 3106 | E5FQ95 P01889 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HLA-B |
|---|---|
| DrugBank ID | DB01048 |
| Drug Name | Abacavir |
| Target ID | BE0009142 |
| UniProt ID | P01889 |
| Regulation Type | |
| PubMed IDs | 19629158 |
| Citations | Yang L, Chen J, He L: Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome. PLoS Comput Biol. 2009 Jul;5(7):e1000441. doi: 10.1371/journal.pcbi.1000441. Epub 2009 Jul 24. |
| Groups | Approved; Investigational |
| Direct Classification | 1,3-substituted cyclopentyl purine nucleosides |
| SMILES | NC1=NC2=C(N=CN2[C@@H]2C[C@H](CO)C=C2)C(NC2CC2)=N1 |
| Pathways | Abacavir Action Pathway |
| PharmGKB | PA448004 |
| ChEMBL | CHEMBL1380 |
