| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018758 | HBV | ENSG00000096384.20 | protein_coding | HSP90AB1 | No | No | 3326 | P08238 Q6PK50 |
| TVIS30013443 | HIV | ENSG00000096384.20 | protein_coding | HSP90AB1 | No | No | 3326 | P08238 Q6PK50 |
| TVIS44034142 | HTLV-1 | ENSG00000096384.20 | protein_coding | HSP90AB1 | No | No | 3326 | P08238 Q6PK50 |
| TVIS44034143 | HTLV-1 | ENSG00000096384.20 | protein_coding | HSP90AB1 | No | No | 3326 | P08238 Q6PK50 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HSP90AB1 |
|---|---|
| DrugBank ID | DB02424 |
| Drug Name | Geldanamycin |
| Target ID | BE0001898 |
| UniProt ID | P08238 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental; Investigational |
| Direct Classification | Macrolactams |
| SMILES | CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)C(C)=CC=C/[C@H](OC)[C@@H](OC(N)=O)C(C)=C[C@H](C)[C@H]1O)C2=O |
| Pathways | |
| PharmGKB | PA152031327 |
| ChEMBL | CHEMBL278315 |