| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10001779 | HBV | ENSG00000115594.12 | protein_coding | IL1R1 | No | No | 3554 | B8ZZW4 P14778 |
| TVIS10023576 | HBV | ENSG00000115594.12 | protein_coding | IL1R1 | No | No | 3554 | B8ZZW4 P14778 |
| TVIS10028623 | HBV | ENSG00000115594.12 | protein_coding | IL1R1 | No | No | 3554 | B8ZZW4 P14778 |
| TVIS20039380 | HPV | ENSG00000115594.12 | protein_coding | IL1R1 | No | No | 3554 | B8ZZW4 P14778 |
| TVIS20055489 | HPV | ENSG00000115594.12 | protein_coding | IL1R1 | No | No | 3554 | B8ZZW4 P14778 |
| TVIS44008101 | HTLV-1 | ENSG00000115594.12 | protein_coding | IL1R1 | No | No | 3554 | B8ZZW4 P14778 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IL1R1 |
|---|---|
| DrugBank ID | DB00026 |
| Drug Name | Anakinra |
| Target ID | BE0000565 |
| UniProt ID | P14778 |
| Regulation Type | antagonist |
| PubMed IDs | 17498496; 12817089; 12355453; 17083033; 11752352; 17352828; 10210771 |
| Citations | Tang YH, Zhang SP, Liang Y, Deng CQ: [Effects of Panax notoginseng saponins on mRNA expressions of interleukin-1 beta, its correlative factors and cysteinyl-aspartate specific protease after cerebral ischemia-reperfusion in rats]. Zhong Xi Yi Jie He Xue Bao. 2007 May;5(3):328-32.@@Dayer JM: The pivotal role of interleukin-1 in the clinical manifestations of rheumatoid arthritis. Rheumatology (Oxford). 2003 May;42 Suppl 2:ii3-10.@@Vamvakopoulos J, Green C, Metcalfe S: Genetic control of IL-1beta bioactivity through differential regulation of the IL-1 receptor antagonist. Eur J Immunol. 2002 Oct;32(10):2988-96.@@Do H, Vasilescu A, Carpentier W, Meyer L, Diop G, Hirtzig T, Coulonges C, Labib T, Spadoni JL, Therwath A, Lathrop M, Matsuda F, Zagury JF: Exhaustive genotyping of the interleukin-1 family genes and associations with AIDS progression in a French cohort. J Infect Dis. 2006 Dec 1;194(11):1492-504. Epub 2006 Oct 26.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@So A, De Smedt T, Revaz S, Tschopp J: A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res Ther. 2007;9(2):R28.@@Vannier E, Kaser A, Atkins MB, Fantuzzi G, Dinarello CA, Mier JW, Tilg H: Elevated circulating levels of soluble interleukin-1 receptor type II during interleukin-2 immunotherapy. Eur Cytokine Netw. 1999 Mar;10(1):37-42. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA10799 |
| ChEMBL | CHEMBL1201570 |
